Thrombosis

Rivaroxaban Supplemental New Drug Application Submitted to FDA for VTE Prophylaxis

Rivaroxaban Supplemental New Drug Application Submitted to FDA for VTE Prophylaxis

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The sNDA submission was supported by Phase 3 data from the MAGELLAN and MARINER trials which assessed the use of rivaroxaban in preventing VTE in acute medically ill patients while hospitalized and immediately after discharge.

FDA Approves Generic Aminocaproic Acid Tablet

FDA Approves Generic Aminocaproic Acid Tablet

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Aminocaprioc Acid Tablets are useful in enhancing hemostasis when fibrolysis contributes to bleeding.

Patient-Centered Education Increases VTE Prophylaxis in Hospital Setting

Patient-Centered Education Increases VTE Prophylaxis in Hospital Setting

A patient-centered education bundle intervention can reduce nonadministration of venous thromboembolism prophylaxis.

Splanchnic Vein Thrombosis May Increase Risk for Arterial Cardiovascular Events

Splanchnic Vein Thrombosis May Increase Risk for Arterial Cardiovascular Events

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Patients with splanchnic vein thrombosis may be at an increased risk for bleeding and arterial cardiovascular events for years after diagnosis.

Questions Remain Regarding VTE Recurrence in Older Adults

Questions Remain Regarding VTE Recurrence in Older Adults

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Venous thromboembolism recurrence risk may not be any higher in older patients than in younger patients.

Baseline Thrombocytopenia Associated With Mortality Risk in VTE

Baseline Thrombocytopenia Associated With Mortality Risk in VTE

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Patients with VTE with moderate to severe thrombocytopenia at baseline were associated with increased risk for major bleeding events and all-cause mortality.

VTE Increases Risk for Chronic Thromboembolic Pulmonary Hypertension

VTE Increases Risk for Chronic Thromboembolic Pulmonary Hypertension

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A number of risk factors were associated with chronic thromboembolic pulmonary hypertension, including, age >70 years, female gender, and pulmonary embolism at first venous thromboembolism.

Transfeminine Persons Have Increased VTE Incidence

Transfeminine Persons Have Increased VTE Incidence

More pronounced differences in venous thromboembolism and ischemic stroke in individuals who initiated hormone treatment during follow-up.

Pulmonary Embolism AEs Increase With DOAC Doses Against Manufacturer Recs

Pulmonary Embolism AEs Increase With DOAC Doses Against Manufacturer Recs

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Patients treated for acute pulmonary embolism with direct oral anticoagulants at doses against manufacturer recommendations had a higher rate of major bleeding events.

VTE Linked to Acute Decline in Physical Function in Women

VTE Linked to Acute Decline in Physical Function in Women

Greater difference in physical decline for women specifically reporting pulmonary embolism.

Perioperative Red Blood Cell Transfusions Linked to Postoperative VTE

Perioperative Red Blood Cell Transfusions Linked to Postoperative VTE

Perioperative red blood cell transfusion linked to increased adjusted odds of venous thromboembolism, deep vein thrombosis, and pulmonary embolism.

Perioperative VTE Prophylaxis Assessment in Post-Pubertal Adolescents

Perioperative VTE Prophylaxis Assessment in Post-Pubertal Adolescents

A decision-making algorithm on venous thromboembolism prophylaxis was developed by the Association of Paediatric Anaesthetists of Great Britain and Ireland.

Reduced-Dose Anticoagulants Feasible for Extended VTE Treatment

Reduced-Dose Anticoagulants Feasible for Extended VTE Treatment

Reduced doses be as effective as full-dose direct oral anticoagulants for extended-duration venous thromboembolism treatment.

Rivaroxaban Linked to Low VTE Recurrence in Active Cancer

Rivaroxaban Linked to Low VTE Recurrence in Active Cancer

Rivaroxaban was associated with lower rates of VTE recurrence, but higher clinically relevant non-major bleeding vs dalteparin.

First Generic Alternative for Mephyton Now Available

First Generic Alternative for Mephyton Now Available

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Amneal's generic product is available in a 5mg strength tablet supplied in 100-count bottles.

Independent Predictors of VTE Identified in Systemic Sclerosis

Independent Predictors of VTE Identified in Systemic Sclerosis

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Researchers evaluated the prevalence, risk factors, and effect of venous thromboembolism on survival in systemic sclerosis.

Deep Venous Thrombosis Ultrasound Protocol Recommendations

Deep Venous Thrombosis Ultrasound Protocol Recommendations

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The Society of Radiologists in Ultrasound has endorsed recommendations regarding ultrasound imaging test protocols for patients with suspected deep venous thrombosis.

Reducing Venous Thromboembolism Risk in Emergency General Surgery

Reducing Venous Thromboembolism Risk in Emergency General Surgery

Unfractionated or low-molecular-weight heparin should be considered to prevent venous thromboembolism in patients admitted for emergency general surgery.

A 64-Year-Old Woman With Colorectal Cancer Presents to ED With Severe Chest Pain

A 64-Year-Old Woman With Colorectal Cancer Presents to ED With Severe Chest Pain

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A 64-year-old woman who was recently diagnosed with colorectal cancer is brought to the emergency department with substernal chest pain and shortness of breath.

Venous Thromboembolism Prevention After Joint Arthroplasty With Rivaroxaban or Aspirin

Venous Thromboembolism Prevention After Joint Arthroplasty With Rivaroxaban or Aspirin

Extended prophylaxis with aspirin does not differ significantly from rivaroxaban for venous thromboembolism prevention in patients who have undergone total hip or knee arthroplasty.

Cardiovascular Risk Predictors in Cancer Survivors

Cardiovascular Risk Predictors in Cancer Survivors

A history of cancer was associated with higher fibrinogen concentration, von Willebrand factor, and antithrombin activity, independent of cardiovascular risk factors.

Atrial Fibrillation Treated With LAA Occlusion Reduces Thromboembolism Risk

Atrial Fibrillation Treated With LAA Occlusion Reduces Thromboembolism Risk

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Surgical left atrial appendage occlusion is associated with a lower risk for thromboembolism-related hospital readmission in older patients with atrial fibrillation who undergo cardiac surgery.

A 35-Year-Old Pregnant Woman Presents With Progressive Dyspnea and Palpitations

A 35-Year-Old Pregnant Woman Presents With Progressive Dyspnea and Palpitations

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A 35-year-old pregnant woman presents to the emergency department with progressive dyspnea and palpitations that have worsened during the last 3 weeks.

Compression Ultrasounds for DVT Diagnosis Can Be Reliably Performed by Nonexperts

Compression Ultrasounds for DVT Diagnosis Can Be Reliably Performed by Nonexperts

General practitioners perform compression ultrasonography for DVT of the leg just as well as vascular experts.

Oral Edoxaban Noninferior to Dalteparin for Cancer-Related Venous Thromboembolism

Oral Edoxaban Noninferior to Dalteparin for Cancer-Related Venous Thromboembolism

Oral edoxaban is noninferior to subcutaneous dalteparin for recurrent venous thromboembolism.

Antithrombotic Agent Discontinuation Unnecessary in Carpal Tunnel Release Surgery

Antithrombotic Agent Discontinuation Unnecessary in Carpal Tunnel Release Surgery

Antithrombotic agents may be safely continued in patients undergoing wide-awake carpal tunnel release surgery.

Antithrombotic Therapy for Atrial Fibrillation and Valvular Heart Disease: New Joint Consensus Statement

Antithrombotic Therapy for Atrial Fibrillation and Valvular Heart Disease: New Joint Consensus Statement

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A new consensus statement provides updated guidelines for antithrombotic therapy in patients with atrial fibrillation associated with valvular heart disease.

Thrombectomy Improves Disability Outcomes After Stroke With Mismatch Between Deficit and Infarct

Thrombectomy Improves Disability Outcomes After Stroke With Mismatch Between Deficit and Infarct

Thrombectomy plus standard care is associated with better outcomes than standard care alone in patients with acute stroke.

Venous Thromboembolism Risk Linked to Lengthy Television Watching

Venous Thromboembolism Risk Linked to Lengthy Television Watching

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Watching television frequently is independently associated with an increased risk for venous thromboembolism.

Vessel Sizing Optimization in BVS Implantation

Vessel Sizing Optimization in BVS Implantation

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Researchers analyzed 3-year outcomes in patients implanted with bioresorbable vascular scaffolds for the treatment of coronary lesions.

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