Off-Label Metformin for Prediabetes With High BMI Improves Cardiovascular Outcomes
Researchers analyzed data taken from EHR insurance claims of 149,654 patients aged 25 years and older between January 2016 and September 2020.
Vascular Medicine
Ankle-Brachial Index: A Predictor for HF, CHD, and Stroke Risk
Researchers analyzed the association between ankle-brachial index and risk for CVD outcomes in older adults with and without ASCVD.
High Remnant Cholesterol Linked to 5-Fold Increased Risk for PAD
Researchers aimed to determine if remnant cholesterol was associated with increased risk for peripheral artery disease.
Link Between Vascular Pathophysiology and Bone Metabolism Studied in Patients With Arthritis
Researchers determined the correlation between vascular pathophysiology and bone metabolism in patients with rheumatoid arthritis and ankylosing spondylitis.
Guideline-Directed Imaging Surveillance After Acute Type A Aortic Dissection Repair
Rates of adherence to guideline-directed imaging surveillance after acute type A aortic dissection repair were evaluated in a retrospective cohort study.
Smoking Before Revascularization Raises Complication Risks
Researchers sought to assess whether smoking before open and endovascular revascularization for intermittent claudication increased risk for postprocedural complications.
Orphan Drug Designation Granted to Gene Therapy for Thromboangiitis Obliterans
Buerger disease typically affects young or middle aged male cigarette smokers.
Varenicline Combination, Extension No Better for Quitting Smoking
Combining varenicline with nicotine patch, extending treatment from 12 to 24 weeks did not increase smoking cessation rates
D-Dimer Level Not Useful for Ruling Out PE in COVID-19
Overall, 92.3 percent of patients had plasma D-dimer levels ≥0.05 µg/mL, including all with and 91.2 percent without, pulmonary embolism.
Avacopan Approved as Adjunct Therapy for ANCA-Associated Vasculitis
The approval was based on data from the phase 3 ADVOCATE trial, which evaluated Tavneos in 330 adults with newly diagnosed or relapsed ANCA-associated vasculitis.
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