Cognitive Decline May Be Slower With Blood-Brain Barrier Crossing Antihypertensive Drugs
Researchers assessed the ability of antihypertensive drugs to cross the blood-brain barrier.
Treatments
Elective Revascularization Decreases Cardiac Mortality of CAD Patients
The researchers reviewed all trials comparing elective coronary revascularization plus medical therapy vs medical therapy alone for managing stable patients with coronary artery disease to determine the value of these approaches.
Some Disease-Modifying Antirheumatic Drugs Raise Risk for Heart Failure
Researchers aimed to study the associations between heart failure medications and certain systemic autoimmune rheumatic diseases.
Bempedoic Acid Decreases Lipid Levels Among Patients With Hyperlipidemia
In a review and meta-analysis, investigators evaluated the novel fatty acid inhibitor bempedoic acid as a possible treatment for hyperlipidemia.
Lower Major Bleeding Event Risk in ACS With Single Antiplatelet Therapy vs DAPT
Study authors analyzed the safety and efficacy of single vs dual antiplatelet therapy (SAPT vs DAPT) in patients with acute coronary syndrome (ACS).
Revacept Therapy Not Associated With Reduction in Myocardial Injury in Stable Ischemic Heart Disease
The objective of this study was to test the efficacy and safety of revacept, a novel, lesion-directed antithrombotic drug, acting as a competitive antagonist to platelet glycoprotein VI.
Dapagliflozin Reduces Risk of Worsening HF and CV Death in HFrEF in Both Sexes
The objective of this study was to investigate the efficacy and safety of dapagliflozin compared with placebo in men and women with HFrEF enrolled in the Dapagliflozin and Prevention of Adverse Outcomes in Heart Failure trial.
CRT With His-Pacing: Good Alternative to Biventricular Pacing With HF
His-pacing correcting left bundle branch block is a promising alternative to biventricular pacing in selected patients with heart failure, according to a new study.
Mortality Linked to Prior Oral Anticoagulant Use in Patients With Intracerebral Hemorrhage
This study evaluated the association between prior oral anticoagulant use and in-hospital outcomes among patients with nontraumatic intracerebral hemorrhage.
Canagliflozin May Not Reduce Myocardial Infarction Risk in Patients With Type 2 Diabetes
Treatment with canagliflozin may not significantly lower risk for myocardial infarction among patients with type 2 diabetes and comorbid chronic kidney disease or among patients with diabetes who have a history of or have a high risk for CVD.
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