Managing Venous Thromboembolism in Transgender Women Receiving Hormone Therapy
Transgender women receiving hormone replacement therapy may be at an increased risk for thromboembolism, though data and recommendations vary across studies.
Thromboembolism
Higher VTE Risk Associated Most With Older Age, Smoking, and Adiposity
Investigators examined a link between major cardiovascular risk factors, such as older age and smoking, and venous thromboembolism, consisting of deep vein thrombosis or pulmonary embolism.
Higher Risk for VTE With Oral vs Transdermal Hormone Replacement Therapy
Oral preparations of hormone replacement therapy for the treatment of menopausal symptoms are associated with a greater risk for VTE compared with transdermal formulations.
ASH Develops Practice Guidelines for Venous Thromboembolism
The American Society of Hematology has developed new guidelines for the treatment of venous thromboembolism.
Apixaban Prevents VTE in Patients With Malignancies Initiating Chemotherapy
Among patients with cancer starting chemotherapy who are at intermediate-to-high risk, rates of venous thromboembolism are significantly lower for thromboprophylaxis with apixaban versus placebo.
Rivaroxaban Supplemental New Drug Application Submitted to FDA for VTE Prophylaxis
The sNDA submission was supported by Phase 3 data from the MAGELLAN and MARINER trials which assessed the use of rivaroxaban in preventing VTE in acute medically ill patients while hospitalized and immediately after discharge.
Patient-Centered Education Increases VTE Prophylaxis in Hospital Setting
A patient-centered education bundle intervention can reduce nonadministration of venous thromboembolism prophylaxis.
Questions Remain Regarding VTE Recurrence in Older Adults
Venous thromboembolism recurrence risk may not be any higher in older patients than in younger patients.
Rivaroxaban in VTE: Lower Clinical Event Costs, But Higher Healthcare Costs
Rivaroxaban was associated with lower clinical event costs but higher total healthcare costs compared with aspirin in patients with venous thromboembolism.
Aspirin, Anticoagulants Similarly Prevent VTE After Knee Arthroplasty
Among patients undergoing total knee arthroplasty, aspirin alone may provide protection against postoperative VTE that is similar to that of other anticoagulants.
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