Stroke Archives - The Cardiology Advisor

Individuals on PrEP who become infected with HIV, such as those with poor adherence to treatment, may have delayed seroconversion on blood-based and oral-fluid-based rapid antibody tests.2 In one study, oral antibody reactivity was first observed a median of 125 days (range, 14-547 days) after HIV RNA or antibodies were observed in the blood.13 In another study, individuals who received PrEP were 3.49 times more likely than those on placebo to experience a delay of >100 days in detecting the infection.14 Based on these and other findings in the literature, it has been suggested that laboratory-based serum or plasma HIV tests should be used whenever possible to monitor individuals on PrEP.2 Additionally, in the setting of known or suspected poor PrEP adherence, the threshold for augmenting p24/IgM/IgG assays with NAT should be lowered.2

General Cardiology

Plasma ACE2 Found to Be Associated With Risk for Major Cardiovascular Events

By

Jessica Nye, PhD

October 28, 2020

Plasma ACE2 concentration was found to be associated with risk for major cardiovascular events.

Stroke

Weekend Admission for Stroke Tied to Higher Mortality

October 27, 2020

Admission for hemorrhagic stroke on weekends versus weekdays tied to higher mortality at both rural and urban hospitals.

Vascular Medicine

Bilateral Internal Thoracic Artery Grafting May Increase the Risk for Acute Lower Limb Ischemia in PAD

By

Jessica Nye, PhD

October 23, 2020

Coronary revascularization with a bilateral internal thoracic artery approach was found to increase the risk for post-operative acute lower limb ischemia in patients with peripheral artery disease.

ACS

Efficacy of Ticagrelor, Prasugrel for the Treatment of Acute Coronary Syndrome With Comorbid Diabetes

By

Jessica Nye, PhD

October 22, 2020

Ticagrelor and prasugrel may have altered efficacy for the treatment of acute coronary syndrome in patients with diabetes mellitus.

Valvular Heart Disease

Deferral of AVR for Severe Aortic Stenosis During COVID-19 Associated With Worsening Heart Failure

By

Brandon May

October 20, 2020

Patients with symptomatic severe aortic stenosis who had aortic valve replacement deferred vs expedited at the beginning of the COVID-19 pandemic were more likely to be hospitalized for valve-related symptoms or worsening heart failure.

CHD

Colchicine Treatment May Lower Risk for Cardiovascular Events in Chronic Coronary Disease

By

Jessica Nye, PhD

October 19, 2020

Daily colchicine treatment may reduce the risk for cardiovascular events in patients with chronic coronary disease.

Arrhythmia

Edoxaban for Stroke Prevention in Elderly Patients With Nonvalvular Atrial Fibrillation

By

Brandon May

October 19, 2020

Edoxaban was more effective than placebo for the prevention of stroke and systemic embolism in elderly patients with nonvalvular atrial fibrillation.

Stroke

Stroke Incidence Slightly Higher in Hospitalized Patients With COVID-19

By

Brandon May

October 19, 2020

Patients hospitalized with COVID-19, especially of older age and with stroke risk factors, have a slightly higher frequency of stroke compared with the general population.

Stroke

Remote Ischemic Postconditioning May Aid Stroke Recovery

October 15, 2020

For patients with acute ischemic stroke (AIS) undergoing intravenous thrombolysis (IVT), remote ischemic postconditioning (RIPC) is associated with improved clinical prognosis.

Stroke

Similar Outcomes for Ischemic Stroke Hospitalizations With and Without Systemic Sclerosis

By

Alyssa Capel

October 14, 2020

Researchers compared the hospitalization outcomes of patients with ischemic stroke with and without a secondary diagnosis of systemic sclerosis.