FDA to Review Dry Powder Inhalation Formulation of Treprostinil
Tyvaso DPI is an investigational drug-device combination therapy consisting of a dry powder formulation of treprostinil.
Pulmonary Vasculature
Safety and Feasibility of Treprostinil Pump Implantation in PAH
Avoiding intubation and mechanical ventilation during subcutaneous pump implantation under local anesthesia and conscious analgosedation was feasible in patients with pulmonary arterial hypertension.
Sotatercept Leads to PVR Reductions in Pulmonary Arterial Hypertension
In patients with pulmonary arterial hypertension (PAH) receiving background therapy, treatment with sotatercept led to significant reductions in pulmonary vascular resistance.
Pulmonary Hypertension Linked to Increased Kidney Faiure, Hospitalization Risk in CKD
The association of pulmonary hypertension with an increased risk for kidney failure in older adults with chronic kidney disease is a novel finding.
Riociguat May Be Useful Alternative to PDE5i Therapy in Pulmonary Arterial Hypertension
Riociguat may be a useful option for patients with pulmonary arterial hypertension in whom phosphodiesterase-5 inhibitor treatment is insufficient.
Mortality Trends in Patients Hospitalized With High-Risk Pulmonary Embolism
Although the mortality of patients with high-risk pulmonary embolism has decreased over time, the decrease cannot be attributed to improved treatments for pulmonary embolism.
Examining Changes in PASP After Atrial Defect Closure in Older Patients With Systolic, Diastolic, and Renal Dysfunction
Patients who are older and have systolic, diastolic, and renal dysfunction may benefit from peri-interventional preload reduction therapy before implantation of larger left atrial devices.
Exercise Doppler Echocardiography Found to Consistently Assess Right Heart, Pulmonary Circulation
Exercise Doppler echocardiography may provide consistent assessment of right heart function and pulmonary circulation when conducted at expert centers.
High Hepatic Growth Factor Levels Add Predictive Value to PAH Risk Score
In pulmonary arterial hypertension, high plasma levels of hepatic growth factor are associated with the right heart maladaptive phenotype and are incremental to the REVEAL score for the prediction of patient outcomes.
Inhaled Treprostinil Beneficial in Pulmonary Hypertension
Exercise capacity improved, clinical worsening reduced for patients with pulmonary HTN due to interstitial lung disease.
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