Presence of Pleural vs Pericardial Effusion in Pulmonary Hypertension
Researchers examined the link between pulmonary hemodynamic variables and the presence of pericardial and pleural effusion.
Pulmonary Hypertension
Pre Capillary Pulmonary Hypertension: Patient Characteristics and Prognosis
Is the 2018 World Symposium on Pulmonary Hypertension definition of pre-capillary pulmonary hypertension beneficial in clinical practice?
Longitudinal Value of Questionnaires for Health-Related QoL in PAH
Health-related quality of life questionnaires created for pulmonary hypertension may be useful for clinicians in daily practice.
Inhaled Imatinib Designated an Orphan Drug for PAH
AER-901 is an investigational drug-device combination therapy that consists of a nebulized formulation of imatinib and the Fox device, a breath-actuated smart nebulizer.
FDA Approves IV Formulation of Uptravi for Pulmonary Arterial Hypertension
The approval was based on data from a single sequence cross-over phase 3 study that evaluated the safety, tolerability and pharmacokinetics of temporarily switching between the tablet and IV formulation.
CFTR Expression in the Pathogenesis of Pulmonary Arterial Hypertension
Researchers sought to delineate the role of cystic fibrosis transmembrane conductance regulator (CFTR) in pulmonary arterial hypertension pathogenesis through observational and interventional experiments in human tissues and animal models.
Safety and Feasibility of Treprostinil Pump Implantation in PAH
Avoiding intubation and mechanical ventilation during subcutaneous pump implantation under local anesthesia and conscious analgosedation was feasible in patients with pulmonary arterial hypertension.
Sotatercept Leads to PVR Reductions in Pulmonary Arterial Hypertension
In patients with pulmonary arterial hypertension (PAH) receiving background therapy, treatment with sotatercept led to significant reductions in pulmonary vascular resistance.
Pulmonary Hypertension Linked to Increased Kidney Faiure, Hospitalization Risk in CKD
The association of pulmonary hypertension with an increased risk for kidney failure in older adults with chronic kidney disease is a novel finding.
Pulmonary Hypertension Increases Mortality Risk in Patients Undergoing Mitral Valve Surgery
The researchers’ goals included determining how postoperative residual pulmonary hypertension was related to longitudinal mortality in patients with severe mitral regurgitation who had mitral valve surgery.
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