Systematic Review of Alternative Therapies for Weight Loss
Investigators assess the efficacy of dietary supplements and alternative therapies for weight loss.
Metabolic
Tesomet Receives Orphan Drug Status for Hypothalamic Obesity
Tesomet is an investigational fixed-dose combination therapy of tesofensine, a triple monoamine reuptake inhibitor, and metoprolol, a beta-1 selective blocker.
LDL-C and CV Health Dependent on Age and Specified Endpoint
The researchers wanted to determine the value of LDL-C as a risk biomarker for coronary heart disease, atherosclerotic cardiovascular disease, and stroke events and deaths for people stratified by age.
Extended-Release Exenatide Approved for Adolescents With T2D
The expanded approval was based on data from a phase 3 study that evaluated exenatide extended-release in 82 patients aged 10 to 17 years with type 2 diabetes.
Major Cardiovascular Events Linked to Metabolic Acidosis
Cardiovascular events are the leading cause of death among patients with chronic kidney disease, and metabolic acidosis in this population is underdiagnosed.
Prior Statin Use Linked to Reduced Risk for Death in COVID-19
For patients hospitalized with COVID-19, prior use of statins, with or without antihypertensives, is associated with a reduced risk for death.
FDA Requests Removal of Pregnancy Contraindication for Statins
The FDA conducted a comprehensive review of all available data associated with the use of statins during pregnancy.
Effect of a Phytochemical-Rich Diet on CV Risk Factors in Type 1 Diabetes
Investigators aimed to assess the relationship between the dietary phytochemical index and cardiovascular disease risk factors in patients with type 1 diabetes.
Severe NAFLD Associated With High Subclinical Atherosclerosis Risk
The goal of this study was to determine the relationship between subclinical coronary artery disease and the severity of nonalcoholic fatty liver disease.
Omega-3 Fatty Acids Tied to Better Cardiovascular Outcomes
Omega-3 fatty acids (FAs) are associated with lower cardiovascular mortality and improved cardiovascular outcomes.
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