Cholesterol Management Guidelines
Recommendations from the American College of Cardiology/American Heart Association Task Force on the management of blood cholesterol.
Dyslipidemia
Statins Found to Be Safe and Effective for the Treatment of Children With Familial Hypercholesterolemia
Pediatricians should be familiar with familial hypercholesterolemia and prescribe statins to treat this disorder.
Leveraging Machine Learning to Identify Familial Hypercholesterolemia
A machine learning model trained to identify patients with familial hypercholesterolemia using large deidentified healthcare encounter data was found to be successful.
Risk for Large Vessel Peripheral Arterial Occlusion in COVID-19 With Elevated Inflammatory Markers
Patients with COVID-19 and comorbidities who present with elevated levels of inflammatory markers and D-dimer may have an increased risk for large vessel peripheral arterial occlusion.
Combined Hyperlipidemia Found to Be Genetically Similar to Isolated Hypertriglyceridemia
Combined hyperlipidemia was found to be similar genetically to isolated hypertriglyceridemia.
Evinacumab Lowers LDL Cholesterol in Refractory Hypercholesterolemia
In this phase 2 trial, patients with hypercholesterolemia and clinical atherosclerotic cardiovascular disease were recruited from 85 sites across 20 countries.
Metformin Treatment in Patients With T2DM at Risk for Heart Failure
Patients with type 2 diabetes mellitus at risk for heart failure treated with metformin may have reduced deterioration of LV filling pressures and myocardial relaxation.
Remnant Cholesterol Concentration an Independent Predictor of Poor Cardiovascular Outcomes
Poor cardiovascular outcomes are more likely in patients with elevated remnant cholesterol or triglycerides.
Statin Use for Primary Prevention of CVD Lower for Sexual Minorities
The lesbian, gay, and bisexual (LGB) population has a lower prevalence of statin use for primary prevention of cardiovascular disease.
LDL-C Polygenic Risk Score and ASCVD in Monogenic Familial Hypercholesterolemia
Elevated LDL-C polygenic scores associated with higher LDL-C levels and increased risk for ASCVD in patients with monogenic familial hypercholesterolemia.
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