Risk of Major Adverse Cardiovascular Events Increased With Renal Function Decline
Patients with rapid decline in estimated glomerular filtration rate had adjusted risk of major adverse cardiovascular events that was 4.11 times higher.
Patients with rapid decline in estimated glomerular filtration rate had adjusted risk of major adverse cardiovascular events that was 4.11 times higher.
Treatment with sulfonylureas may inhibit the neuroprotective effects of KATP channel activation and increase stroke risk in patients with diabetes.
Percutaneous coronary intervention use has increased among patients with diabetes and multivessel coronary artery disease who present with non-ST-segment elevation myocardial infarction.
Compared with nonuse, current SSRI use correlated with increased 30-day stroke mortality (adjusted mortality rate ratio: 1.3), with the highest risk for new users.
Individuals who carried the most favorable adiposity alleles had higher body mass indexes and body fat percentages.
All age groups had significant decreases in all-cause, cardiovascular disease, and diabetes mortality rates except for diabetes mortality in younger individuals (ages 0 to 40).
The risk for obesity was greater among those with psoriasis—11.6% of people with psoriasis were obese, but only 8.1% of non-obese individuals had psoriasis.
From the disease risk score-stratified analyses, the hazard ratios were 0.83, 0.63, 0.69, and 0.61 for saxagliptin vs sitagliptin, pioglitazone, sulfonylureas, and insulin, respectively.
Everolimus-eluting stents reduced the rate of target vessel failure, stent thrombosis, target lesion and vessel revascularization in patients with insulin-treated diabetes.
Imaging to guide primary heart failure prevention in older asymptomatic patients with type 2 diabetes may be cost-effective