Risk of Major Adverse Cardiovascular Events Increased With Renal Function Decline
Patients with rapid decline in estimated glomerular filtration rate had adjusted risk of major adverse cardiovascular events that was 4.11 times higher.
Diabetes
Sulfonylureas May Increase Risk of Stroke in Patients With Diabetes
Treatment with sulfonylureas may inhibit the neuroprotective effects of KATP channel activation and increase stroke risk in patients with diabetes.
Revascularization Strategies for Patients With Coronary Artery Disease and Diabetes
Percutaneous coronary intervention use has increased among patients with diabetes and multivessel coronary artery disease who present with non-ST-segment elevation myocardial infarction.
Selective Serotonin Reuptake Inhibitors Associated With Increased Stroke Mortality in Diabetes Patients
Compared with nonuse, current SSRI use correlated with increased 30-day stroke mortality (adjusted mortality rate ratio: 1.3), with the highest risk for new users.
Adiposity Variant Genetic Score Linked to Lower Cardiometabolic Disease Risk
Individuals who carried the most favorable adiposity alleles had higher body mass indexes and body fat percentages.
Cardiovascular Disease Mortality in Diabetes Patients Declined from 2000 to 2011
All age groups had significant decreases in all-cause, cardiovascular disease, and diabetes mortality rates except for diabetes mortality in younger individuals (ages 0 to 40).
Possible Genetic Link Between Obesity, Type 2 Diabetes, and Psoriasis
The risk for obesity was greater among those with psoriasis—11.6% of people with psoriasis were obese, but only 8.1% of non-obese individuals had psoriasis.
Dipeptidyl Peptidase-4 Inhibitors Do Not Increase Risk of Hospitalized Heart Failure
From the disease risk score-stratified analyses, the hazard ratios were 0.83, 0.63, 0.69, and 0.61 for saxagliptin vs sitagliptin, pioglitazone, sulfonylureas, and insulin, respectively.
Patients With Insulin-Treated Diabetes Had Better Outcomes With Everolimus-Eluting Stents
Everolimus-eluting stents reduced the rate of target vessel failure, stent thrombosis, target lesion and vessel revascularization in patients with insulin-treated diabetes.
Imaging for Heart Failure Prevention in Diabetes Patients May Be Cost-Effective
Imaging to guide primary heart failure prevention in older asymptomatic patients with type 2 diabetes may be cost-effective
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