Reducing Door-to-Needle Time in Acute Stroke With Pharmacist Participation

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The only factor independently associated with reduction in DTN time was pharmacist at the bedside.
The only factor independently associated with reduction in DTN time was pharmacist at the bedside.

HealthDay News — Having a pharmacist at bedside during acute ischemic stroke is associated with significantly shorter door-to-needle (DTN) times, according to a study published recently in the Annals of Pharmacotherapy.

Megan A. Rech, PharmD, from the Loyola Medical Center in Maywood, Ill., and colleagues conducted a retrospective cohort study to examine whether pharmacist presence at bedside during acute ischemic stroke correlated with a reduction in DTN times. Data were included for 125 patients who received recombinant tissue plasminogen activator; 45 and 80 patients had and did not have a pharmacist present (PharmD and no-PharmD groups, respectively).

The researchers found that the median DTN time was significantly shorter in the PharmD group vs the no-PharmD group (48 minutes vs 73 minutes; P <.01). 

Overall, 71% and 29% of patients in the PharmD and no-PharmD groups met the goal of DTN ≤60 minutes (P <.01). The only factor independently associated with reduction in DTN time was pharmacist at the bedside (β coefficient, −23.5 minutes).

"These findings support the inclusion of a stroke-competent pharmacist in the bedside response team for acute ischemic stroke patients," the authors wrote.

Reference

Rech MA, Bennnett S, Donahey E. Pharmacist participation in acute ischemic stroke decreases door-to-needle time to recombinant tissue plasminogen activator. Ann Pharmacother. 2017;51(12):1084-1089.

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