Pulmonary Vasculature

Serum Chloride Linked With Survival in Pulmonary Arterial Hypertension

Serum Chloride Linked With Survival in Pulmonary Arterial Hypertension

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Serum chloride was a strong and independent predictor of mortality at 6 months after a pulmonary arterial hypertension diagnosis.

Egg-and-Banana Sign Has High Specificity for Pulmonary Hypertension Diagnosis

Egg-and-Banana Sign Has High Specificity for Pulmonary Hypertension Diagnosis

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The "egg-and-banana" sign is a valid computed tomography marker of pulmonary hypertension.

Oral Anticoagulant Effective in Recurrent VTE Prevention in Cancer Patients

Oral Anticoagulant Effective in Recurrent VTE Prevention in Cancer Patients

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At the end of 6 months, the rate of VTE recurrence was 4% among rivaroxaban patients vs 11% in the dalteparin arm (hazard ratio [HR] 0.43, 95% CI: 0.19 to 0.99).

Veno-Arterial Extracorporeal Membrane Oxygenation Improves Survival in Pulmonary Embolism

Veno-Arterial Extracorporeal Membrane Oxygenation Improves Survival in Pulmonary Embolism

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A protocolized study including initiation of VA-ECMO may reduce mortality in patients with massive PE.

Predictive Value of Idiopathic PAH Risk Assessment Using Comorbidities, Age

Predictive Value of Idiopathic PAH Risk Assessment Using Comorbidities, Age

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Ischemic heart disease and kidney dysfunction were identified as 2 comorbidities that may affect outcomes in idiopathic pulmonary arterial hypertension.

Stem Cell Therapy for RV Failure in PAH: Overview and Clinician Interview

Stem Cell Therapy for RV Failure in PAH: Overview and Clinician Interview

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Stem cell therapy targeting right ventricular failure may help improve pulmonary circulation in pulmonary arterial hypertension.

Opsumit sNDA Submitted for Chronic Thromboembolic Pulmonary Hypertension

Opsumit sNDA Submitted for Chronic Thromboembolic Pulmonary Hypertension

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The sNDA is accompanied by results from the MERIT-1 trial, a Phase 2 randomized, placebo-controlled, double-blind study which assessed the efficacy, safety and tolerability of macitentan 10mg in 80 patients with inoperable CTEPH.

Pulmonary Arterial Hypertension Prognosis Linked to Walking Distance

Pulmonary Arterial Hypertension Prognosis Linked to Walking Distance

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Walking a distance of >400 meters in the 6-minute walk test was associated with a reduced risk for pulmonary arterial hypertension-related death or hospitalization.

Benefits of Targeted Pharmacologic Therapy in PAH and Distal CTEPH

Benefits of Targeted Pharmacologic Therapy in PAH and Distal CTEPH

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In patients with pulmonary arterial hypertension or distal chronic thromboembolic pulmonary hypertension, targeted pharmacologic treatment was associated with an increase in achieved therapeutic goals.

Perioperative Risk Assessment in a Patient With COPD

Perioperative Risk Assessment in a Patient With COPD

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A 64-year-old man with chronic obstructive pulmonary disease, diabetes, chronic kidney disease, and morbid obesity seeks preoperative approval for femoral popliteal bypass surgery.

Pulmonary hypertension in heart failure with preserved ejection fraction is associated with mortality

Pulmonary hypertension associated with heart failure with preserved ejection fraction (PH-HFpEF) is common in patients undergoing right heart catheterization. Transpulmonary gradient, pulmonary vascular resistance, and diastolic pulmonary gradient are predictors of mortality and cardiac hospitalizations in PH-HFpEF.

Pulmonary Arterial Hypertension Outcomes With Atrial Arrhythmia

Pulmonary Arterial Hypertension Outcomes With Atrial Arrhythmia

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Increased right atrial and pulmonary wedge pressures and increased thyroid disease prevalence were associated with atrial arrhythmia development in idiopathic or systemic sclerosis-related pulmonary arterial hypertension.

Pulmonary Hypertension Outcomes Predicted by NT-pro BNP

Pulmonary Hypertension Outcomes Predicted by NT-pro BNP

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N-terminal-pro brain natriuretic peptide may be a useful biomarker for both mortality and respiratory exacerbations in pediatric patients with pulmonary hypertension.

Pulmonary Hypertension Mortality Following Cardiac Catheterization

Pulmonary Hypertension Mortality Following Cardiac Catheterization

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Patients with pulmonary hypertension have a high risk for adverse events during and following cardiac catheterization, but high case volume may help ameliorate this risk.

Clinical Case: Pregnant Woman Presents With Worsening Dyspnea

Clinical Case: Pregnant Woman Presents With Worsening Dyspnea

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A 32-year-old woman presents to the emergency department with complaints of dyspnea on exertion and near syncopal episodes.

PDE-5 Inhibitor Prescribing Trends Do Not Meet Pulmonary Hypertension Guidelines

PDE-5 Inhibitor Prescribing Trends Do Not Meet Pulmonary Hypertension Guidelines

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Nearly two-thirds of phosphodiesterase-5 inhibitor prescriptions are inconsistent with pulmonary hypertension guidelines.

Pulmonary Arterial Hypertension Identified Via Claims-Based Algorithm

Pulmonary Arterial Hypertension Identified Via Claims-Based Algorithm

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Patients with pulmonary arterial hypertension may be better identified with the use of a claims-based algorithm that includes ICD-9-CM codes, electronic medical records, and more.

Pulmonary Hypertension With HFpEF: Hemodynamic Markers Predict Mortality, Hospitalization

Pulmonary Hypertension With HFpEF: Hemodynamic Markers Predict Mortality, Hospitalization

Transpulmonary gradient, pulmonary vascular resistance, and diastolic pulmonary gradient are associated with mortality in patients with pulmonary hypertension and heart failure with preserved ejection fraction.

Hemodynamic markers of pulmonary hypertension in heart failure with preserved ejection fraction are associated with mortality

Transpulmonary gradient, pulmonary vascular resistance, and diastolic pulmonary gradient are predictors of mortality and cardiac hospitalizations in pulmonary hypertension associated with heart failure with preserved ejection fraction.

Cardiac Surgery During Flu Season May Increase ARDS Risk

Cardiac Surgery During Flu Season May Increase ARDS Risk

There was an increased risk for acute respiratory distress syndrome after undergoing cardiac surgery during influenza season.

Pulmonary Hypertension Treatments Targeting NO Pathway Compared for Safety

Pulmonary Hypertension Treatments Targeting NO Pathway Compared for Safety

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Several drugs may demonstrate different safety profiles and side effects that warrant a change in treatment for individuals with pulmonary hypertension.

Pulmonary Arterial Hypertension: Biomarker May Predict 5-Year Survival

Pulmonary Arterial Hypertension: Biomarker May Predict 5-Year Survival

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Monitoring the plasma BNP level in individuals with pulmonary arterial hypertension may aid clinicians in therapeutic decision-making and overall prediction of 5-year survival rate.

Necessity of Pulmonary Embolism Evaluation in Syncope

Necessity of Pulmonary Embolism Evaluation in Syncope

The prevalence of pulmonary embolism is low in patients presenting to the emergency department with syncope.

Global Pulmonary Vascular Remodeling and Pulmonary Hypertension in Heart Failure

Global Pulmonary Vascular Remodeling and Pulmonary Hypertension in Heart Failure

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Researchers discovered an association between global pulmonary vascular remodeling and pulmonary hypertension in patients with heart failure.

Assessment of Ambrisentan in Pulmonary Arterial Hypertension

Assessment of Ambrisentan in Pulmonary Arterial Hypertension

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In a postmarketing surveillance study, ambrisentan demonstrated tolerability and potential effectiveness for pulmonary arterial hypertension treatment.

Intermediate-Risk Pulmonary Embolism Treatment With Dabigatran

Intermediate-Risk Pulmonary Embolism Treatment With Dabigatran

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Patients diagnosed with an intermediate-risk pulmonary embolism may be able to start oral anticoagulation therapy after completing 72 hours of heparin therapy during hospitalization.

Smoking-Related Lung Microbiota Changes Affect ARDS Development After Blunt Trauma

Smoking-Related Lung Microbiota Changes Affect ARDS Development After Blunt Trauma

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Smoking-related changes in lung microbiota may increase the risk for acute respiratory distress syndrome in patients after severe trauma.

Pulmonary Arterial Hypertension: Mechanisms of Exercise Intolerance

Pulmonary Arterial Hypertension: Mechanisms of Exercise Intolerance

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Exercise intolerance is a hallmark symptom of pulmonary arterial hypertension.

Diagnostic Value of Bronchoalveolar Lavage in Idiopathic Pulmonary Fibrosis

Diagnostic Value of Bronchoalveolar Lavage in Idiopathic Pulmonary Fibrosis

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The diagnostic value of bronchoalveolar lavage in idiopathic pulmonary fibrosis is evaluated.

Clinical Case: Man With COPD and Worsening Shortness of Breath

Clinical Case: Man With COPD and Worsening Shortness of Breath

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A case study is of worsening dyspnea in a patient with COPD is presented.

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