Necessity of Pulmonary Embolism Evaluation in Syncope

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The prevalence of PE varied from 0.06% to 0.55% for all patients and from 0.15% to 2.1% for hospitalized patients.
The prevalence of PE varied from 0.06% to 0.55% for all patients and from 0.15% to 2.1% for hospitalized patients.

HealthDay News — For patients presenting to the emergency department with syncope, the prevalence of pulmonary embolism (PE) is low, according to a study published in JAMA Internal Medicine.

Giorgio Costantino, MD, from the Università degli Studi di Milano in Italy, and colleagues conducted a retrospective observational study and examined longitudinal administrative data from 5 databases in 4 different countries. The authors examined the prevalence of PE among 1,671,944 unselected adults who presented to the emergency department with syncope.

Based on administrative data, the researchers found that the prevalence of PE varied from 0.06% to 0.55% for all patients and from 0.15% to 2.1% for hospitalized patients.

At 90 days of follow-up, PE prevalence varied from 0.14% to 0.83% for all patients and from 0.35% to 2.63% for hospitalized patients. At 90 days, the prevalence of venous thromboembolism varied from 0.3% to 1.37% for all patients and from 0.75% to 3.86% for hospitalized patients.

"Pulmonary embolism was rarely identified in patients with syncope," the authors wrote. "Although PE should be considered in every patient, not all patients should undergo evaluation for PE."

Disclosures: One author disclosed financial ties to Medtronic.

Reference

Costantino G, Ruwald MH, Quinn J, et al. Prevalence of pulmonary embolism in patients with syncope [published online January 29, 2018]. JAMA Intern Med. doi:10.1001/jamainternmed.2017.8175

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