Diseases of Pulmonary Vasculature
Featured Article
Supplementing Pulmonary Arterial Hypertension Therapy With Nutritional Changes
Current research suggests patients with pulmonary arterial hypertension may benefit from iron and vitamin D supplementation.
Latest Features
Supplementing Pulmonary Arterial Hypertension Therapy With Nutritional Changes
Current research suggests patients with pulmonary arterial hypertension may benefit from iron and vitamin D supplementation.
Improving Risk Stratification, Diagnostic Accuracy in PAH With Cardiopulmonary Exercise Testing
Cardiopulmonary exercise testing can be an important diagnostic and prognostic tool in pulmonary arterial hypertension.
Connective Tissue Diseases in Comorbid PAH: A Case for Separating SSc, SLE
Recent evidence suggests that systemic sclerosis and systemic lupus erythematosus comorbid with pulmonary arterial hypertension should be considered separate diseases.
Improved Pulmonary Arterial Hypertension Risk Prediction Tools Needed
The use of a risk calculator aimed at achieving a low-risk profile in PAH trials is discussed.
Lung Transplantation in Pulmonary Arterial Hypertension: An Overview
Evaluating diagnosis and treatment options for pulmonary arterial hypertension.
Worsening Shortness of Breath in a 40-Year-Old Woman: A Case Study
A 40-year-old woman presents with worsening shortness of breath after being treated with long-acting nifedipine for 2 years.
Pulmonary Arterial Hypertension: Mechanisms of Exercise Intolerance
Exercise intolerance is a hallmark symptom of pulmonary arterial hypertension.
Diagnostic Value of Bronchoalveolar Lavage in Idiopathic Pulmonary Fibrosis
The diagnostic value of bronchoalveolar lavage in idiopathic pulmonary fibrosis is evaluated.
Chronic Thromboembolic PH Diagnosis and Management Update: Expert Q&A
Development of CTEPH is associated with traditional thrombotic risk factors, including thrombophilias and inflammatory processes.
Pulmonary Arterial Hypertension: Treatment Tailored by Race and Ethnicity
Future clinical trials on pulmonary arterial hypertension should include patients from diverse racial and ethnic backgrounds.
Latest News
Generic Version of Adcirca Now Available for Pulmonary Arterial Hypertension
Tadalafil, a phosphodiesterase 5 (PDE5) inhibitor, is indicated to treat pulmonary arterial hypertension to improve exercise ability.
Orenitram Decreased Risk of Morbidity/Mortality Event in PAH Trial
FREEDOM-EV was an international, multicenter, randomized, double-blind, placebo-controlled trial (N=690) that randomized patients to 3 daily doses of Orenitram or placebo.
Pulmonary-Systemic Pulse Pressure Ratio Linked to PH Mortality
Patients with group 1 pulmonary hypertension who had a higher pulmonary-systemic pulse pressure ratio had a higher risk for mortality.
Segmental Pulmonary Hypertension: Management of New Classification
Segmental pulmonary hypertension can result from several conditions, such as complex pulmonary atresia, hemitruncus arteriosus, absence/atresia of a single pulmonary artery, and an anomalous pulmonary artery from the aorta feeding a single lung segment.
Implantable System for Remodulin Approved for Patients With PAH
Remodulin is a prostacyclin vasodilator indicated for the treatment of pulmonary arterial hypertension.
Newly Diagnosed, Limitation-Free PH at Risk for Exercise Capacity Reductions
Patients with World Health Organization Functional Class I pulmonary hypertension experienced a significant reduction in exercise capacity following the shuttle walk test.
Tricuspid Regurgitation Velocity Unreliable Indicator of Pulmonary Hypertension
Pulmonary hypertension was confirmed by invasive methods in 68% and 47% of patients with and without a measurable tricuspid regurgitation velocity, respectively.
Early Pulmonary Vascular Disease Onset Risk in Adults Born Preterm
Increased pulmonary pressures, right ventricular dysfunction, and a stiffer pulmonary vascular bed were typical characteristics of early pulmonary vascular disease onset in young adults who were born preterm.
PAH Mortality Rates Comparable With ERA or PDE5 Inhibitor Therapy
There were no significant differences in pulmonary arterial hypertension survival based on therapy type, age was an important modifier.
Pulmonary Arterial Stiffness Related to mPAP and Heart Rate in Idiopathic PAH
Pulmonary arterial stiffness was related to mean pulmonary arterial pressure and heart rate in patients with untreated idiopathic pulmonary arterial hypertension.
Prognostic Model for Mortality in Pediatric Pulmonary Hypertension
The Pediatric Index Pulmonary Hypertension Intensive Care Mortality model was compared with the Pediatric Risk of Mortality 2 and 3 models to determine the best model for predicting mortality.
RV Trabecular Complexity Fractal Analysis: Measuring Remodeling in PH
The fractal dimension of right ventricular trabecular complexity was a good reproducible marker of remodeling in pulmonary hypertension.
RV Base/Apex Ratio May Help Diagnose Pulmonary Arterial Hypertension in Children
Right ventricular base/apex ratio reference values may help clinicians diagnose children with pulmonary arterial hypertension.
Improved Counseling Needed in Pregnant Patients With Pulmonary Arterial Hypertension
Many healthcare providers reported that they often do not have the time to counsel their patients with pulmonary arterial hypertension on pregnancy risks.
PAH in Congenital Heart Disease: Expert Q&A on Challenges and Advances
Management strategies were discussed for subtypes of PAH-congenital heart disease including Eisenmenger syndrome, PAH with persistent systemic to pulmonary shunts, and PAH with small or coincidental defect or PAH after defect closure.
Cyanosis From PH or Congenital Heart Disease Responds Well to IV Ferrous Carboxymaltose
After iron supplementation, patients with cyanosis experienced significant improvements in hemoglobin concentration, hematocrit, mean corpuscular volume, ferritin, and transferrin saturation
Sildenafil, Bosentan Combination vs Sildenafil Monotherapy in SSc-Associated PAH
There was no significant difference in efficacy between sildenafil and bosentan initial combination therapy and sildenafil monotherapy in patients with systemic sclerosis-related pulmonary arterial hypertension.
CTEPH Increases Risk for Sleep Disordered Breathing
Precapillary pulmonary hypertension and obstructive sleep apnea may be causative factors for central sleep apnea and pulmonary hypertension, respectively.
Arrhythmia Associated With Higher Mortality in Congenital Heart Disease-Related PAH
Arrhythmia was a significant predictor of mortality in adult patients with congenital heart disease and pulmonary arterial hypertension.
Composite Echo Score Predicts PH in Interstitial Lung Disease
The variables for the stepwise echocardiographic score included right ventricular systolic pressure, early pulmonary regurgitation gradient, right atrial area size, tricuspid regurgitation velocity, left ventricle eccentricity index, and right ventricle fractional area change.
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