Two 6-Minute Walk Tests Recommended for Suspected Pulmonary Hypertension
In the initial assessment, more than half of the study participants were able to walk farther in the second 6MWT than in the first.
Tadalafil, a phosphodiesterase 5 (PDE5) inhibitor, is indicated to treat pulmonary arterial hypertension to improve exercise ability.
FREEDOM-EV was an international, multicenter, randomized, double-blind, placebo-controlled trial (N=690) that randomized patients to 3 daily doses of Orenitram or placebo.
Patients with group 1 pulmonary hypertension who had a higher pulmonary-systemic pulse pressure ratio had a higher risk for mortality.