A 12-month intensive lifestyle intervention including an energy-restricted Mediterranean diet, increased physical activity, and behavioral support for overweight/obese patients was found to be beneficial in decreasing adiposity and cardiovascular events.
CAC was found to be independently associated with ASCVD events in familiar hypercholesterolemia treated with standard lipid lowering therapy.
Reducing triglyceride levels in patients with type 2 diabetes may help them attain more optimal glycemic control.
Primary lipid screening rates were suboptimal among patients with rheumatoid arthritis.
The addition of ezetimibe to simvastatin reduced ischemic risk compared with placebo, with consistent relative risk reductions in patients with and without polyvascular disease.
The American College of Cardiology published an expert consensus statement regarding decision considerations for novel cardiovascular risk reduction therapies in patients with type 2 diabetes and atherosclerotic cardiovascular disease.
The onset of musculoskeletal adverse events during statin monotherapy is significantly faster with use of atorvastatin and rosuvastatin versus simvastatin.
In patients with primary hypercholesterolemia, short-term treatment with simvastatin improved the lipid profile and exerted a beneficial effect on a wide range of proatherogenic and prothrombotic parameters.
Total cardiovascular event reduction may represent a more comprehensive metric to assess alirocumab clinical efficacy after acute coronary syndrome.
AKCEA-APO(a)-LRX is efficient and safe in patients with established cardiovascular disease and elevated levels of lipoprotein(a).
Updated cholesterol guidelines offer more personalized cardiovascular disease risk assessment.
In high-risk patients with mild hypertriglyceridemia, omega-3 fatty acids improved triglyceride levels and reduced major adverse cardiovascular events, according to a new meta-analysis.
Compared with evolocumab, the addition of ezetimibe to statin therapy is a major cost-saving strategy for preventing cardiovascular (CV) death in patients with T2D and an established CV disease.
The data showed MAEs onset was significantly faster with atorvastatin and rosuvastatin compared with simvastatin; a comparison with other statins could not be established due to the small number of cases identified.
First-year nonadherence and discontinuation are high among older adults prescribed statins.
Investigators sought to determine whether clinician lipid testing practices were consistent with ACC/AHA 2013 recommended testing guidelines for LDL cholesterol.
Skin disorders, particularly those with known inflammatory mechanisms, may be considered potential early markers for the development of insulin resistance leading to metabolic syndrome, type 2 diabetes, and cardiovascular disease.
Statin therapy is associated with reduced mitochondrial complex II-linked respiration, and statin-induced myalgia is coupled to an increased intrinsic mitochondrial respiratory function, while intramuscular [coenzyme Q10] levels are unaltered.
Hyperglycemia, obesity, and hypertriglyceridemia are negatively related to cardiovascular autonomic neuropathy indices.
Repatha is a proprotein convertase subtilisin/kexin type 9 inhibitor.
The randomized, double-blind, placebo-controlled, parallel-group study (N=9340) evaluated the time from randomization to first occurrence of major adverse CV events (MACE) (non-fatal heart attack, non-fatal stroke, CV death) in patients treated with liraglutide 1.8mg once daily or placebo.
In multivariable models, associations were observed between cardiovascular risk factors and cerebrovascular morphology, as well as white matter hyperintensity count.
A computed tomography (CT)-based abdominal aortic calcification (AAC) score is a strong predictor of future cardiovascular events in asymptomatic patients.
The study utilized patient-reported side effects to determine the tolerability of the PCSK9 inhibitors evolocumab and alirocumab.
Heritability of BMI was significantly higher in children living in high-risk obesogenic environments compared with those living in low-risk environments.
High variability of fasting blood glucose and total cholesterol levels, systolic blood pressure, and BMI may be an independent predictor of cardiovascular events.
Supplementation with coenzyme Q10 may be an effective approach for managing statin-induced myopathy.
For this analysis, the authors used follow-up data from all 7020 patients included in the EMPA-REG OUTCOME trial to estimate the effect of empagliflozin on all-cause mortality vs placebo over the duration of a patient's lifetime.
Lorcaserin reduces the risk for diabetes in obese or overweight patients with prediabetes or without diabetes and reduces HbA1c among those with diabetes.
Atopic dermatitis was not found to be an independent risk factor for cardiometabolic disease in this meta-analysis.
The Cardiology Advisor Articles
- Should Guidelines Use Higher Risk Thresholds When Recommending Statins for Primary CVD Prevention?
- Ezetimibe Plus Statins Modestly Reduce Cardiovascular Disease Event Risk
- ACC, AHA Publish Appropriate Use Criteria Guidelines for Peripheral Artery Intervention
- FDA: E-Liquids Found to Contain Undeclared Sildenafil and Tadalafil
- Ultrasound-Based Visualization of Silent Atherosclerosis May Improve Medication Adherence
- ACC Releases Consensus Decision Pathway for CVD Risk Reduction in T2D and ASCVD
- Childhood Behavioral Interventions May Promote Adult Cardiovascular Health
- US Medical Schools Increase in Diversity After Implementation of Accreditation Standards
- Botox Injections Explored to Reduce Postop AF in Cardiac Surgery
- AHA Scientific Statement: Low Risk of Side Effects With Statins
- Do More Aggressive Periprocedural Antibiotic Regimens Reduce Risk of Device-Related Infections?
- Adherence and Intensity of Lipid-Lowering Therapy Influence CV Risk
- Challenges in Weighing Costs, Therapeutic Benefits of Expensive Pharmaceuticals
- Sustained Systolic Blood Pressure Reductions With Barbershop Intervention
- Stethoscopes in ICU Show High Levels of Bacterial Contamination