Metabolic

Casual Glucose Concentrations Predict Post-Surgical Myocardial Injury

Casual Glucose Concentrations Predict Post-Surgical Myocardial Injury

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Glucose concentration assessment before noncardiac surgery may help clinicians predict the risk for postoperative myocardial injury in patients with and without diabetes.

High BMI May Hurt Cardiovascular Health in Teens, Young Adults

High BMI May Hurt Cardiovascular Health in Teens, Young Adults

Using a combination of methodologies suggests higher BMI may increase blood pressure and left ventricular mass index in youth.

Bariatric Surgery Lowers Microvascular Disease Risk

Bariatric Surgery Lowers Microvascular Disease Risk

Bariatric surgery was associated with significantly lower risk for incident microvascular disease at 5 years.

Better Cardiac Profiles With Exercise, Less Sitting in Early Old Age

Better Cardiac Profiles With Exercise, Less Sitting in Early Old Age

Greater light and moderate-to-vigorous intensity physical activity were tied to a more favorable cardiac profile in adults aged 60 to 64.

Healthy Lifestyle With Diabetes Reduces Cardiovascular Risk

Healthy Lifestyle With Diabetes Reduces Cardiovascular Risk

The benefit of adopting a healthy lifestyle was seen even after the type 2 diabetes diagnosis was made.

American Heart Association Urges Screen Time Limits for Youth

American Heart Association Urges Screen Time Limits for Youth

Increasing screen time trends may have a negative cardiometabolic effect on young children.

Elevated HDL-C May Not Benefit Postmenopausal Women

Elevated HDL-C May Not Benefit Postmenopausal Women

Higher HDL cholesterol in postmenopausal women may mask heart disease risk.

CDC: Half of US Adults Tried to Lose Weight From 2013 to 2016

CDC: Half of US Adults Tried to Lose Weight From 2013 to 2016

Exercising and eating less were top weight loss methods, and more women than men attempted weight loss.

Single Threshold May Not Be Feasible for Gestational Diabetes

Single Threshold May Not Be Feasible for Gestational Diabetes

Diagnostic thresholds for gestational diabetes should be adapted using local populations.

Nut Intake Reduces HbA1c Among Adults With T2DM

Nut Intake Reduces HbA1c Among Adults With T2DM

A full-nut dose lowered HbA1c and estimated cholesterol levels in LDL particles of a certain diameter.

Diabetes Diagnosis May Affect Health Behaviors of Family

Diabetes Diagnosis May Affect Health Behaviors of Family

Small changes in health behaviors were seen in partners of those newly diagnosed with diabetes.

Canagliflozin Trial for T2D With CKD Stopped Early Due to Positive Results

Canagliflozin Trial for T2D With CKD Stopped Early Due to Positive Results

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A clinical trial assessing canagliflozin (Invokana; Janssen) as an addition to standard-of-care in patients with chronic kidney disease (CKD) and type 2 diabetes (T2D) has been stopped early after meeting its pre-specified efficacy criteria.

Improving Sleep Quality May Reduce Cardiovascular Risk in Bipolar Disorder

Improving Sleep Quality May Reduce Cardiovascular Risk in Bipolar Disorder

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The relationship between circadian rhythm and sleep measures and components of metabolic syndrome in patients with bipolar disorder.

New Data Support Long-Term Cardiovascular Safety of Linagliptin in T2D

New Data Support Long-Term Cardiovascular Safety of Linagliptin in T2D

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Results showed the overall safety profile of linagliptin in study patients, including adults with kidney disease, was consistent with previous data.

Results From Long-Term Cardiovascular Safety Study of Lorcaserin Announced

Results From Long-Term Cardiovascular Safety Study of Lorcaserin Announced

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Approximately 12,000 patients took part in the CAMELLIA-TIMI 61 trial in which participants were randomized to either lorcaserin HCl 10mg twice daily or placebo.

Mothers' Healthy Lifestyle Tied to Drop in Offspring Obesity

Mothers' Healthy Lifestyle Tied to Drop in Offspring Obesity

Lower risk for incident obesity in offspring whose mothers have healthy BMI and engage in physical activity.

AMA Adopts Policy to Cut Sugar Sweetened Drink Consumption

AMA Adopts Policy to Cut Sugar Sweetened Drink Consumption

The policy supports evidence-based strategies such as excise taxes and adding warning labels.

Beta-Blockers Show Varied Effects on Hypoglycemic Mortality Risk in Diabetes

Beta-Blockers Show Varied Effects on Hypoglycemic Mortality Risk in Diabetes

Investigators examined the relationship between the use of β-blockers and incidence of hypoglycemia and risk for mortality in hospitalized patients with diabetes.

ITCA 650 Shows Efficacy in Reducing Weight, HbA1c in Type 2 Diabetes

ITCA 650 Shows Efficacy in Reducing Weight, HbA1c in Type 2 Diabetes

The ITCA 650, a small titanium osmotic mini-pump, provides a subcutaneous infusion of exenatide over 3 or 6 months.

SGLT2 Inhibitor Use Linked to Lower Risk for Heart Failure, Death in Type 2 Diabetes

SGLT2 Inhibitor Use Linked to Lower Risk for Heart Failure, Death in Type 2 Diabetes

Regardless of presence of preexisting cardiovascular disease, SGLT2 inhibitors were associated with lower risk for death and heart failure.

Cardiovascular Event Risk Down With Med Diet Plus Olive Oil, Nuts

Cardiovascular Event Risk Down With Med Diet Plus Olive Oil, Nuts

Lower incidence of major cardiovascular events with Mediterranean diet supplemented with oil and nuts.

Fenofibrate Improves Cholesterol Levels in Type 2 Diabetes

Fenofibrate Improves Cholesterol Levels in Type 2 Diabetes

To understand the mechanism underlying the benefit of fenofibrate on vascular complications in patients with type 2 diabetes, investigators assessed carotid intima thickness as a marker of subclinical atherosclerosis.

Good Sleep Tied to Better Cardiometabolic Health in Youths

Good Sleep Tied to Better Cardiometabolic Health in Youths

Longer sleep duration and greater sleep efficiency linked to better metabolic risk scores in adolescents.

Plasma Methylglyoxal Levels Associated With CVD, Mortality in Type 2 Diabetes

Plasma Methylglyoxal Levels Associated With CVD, Mortality in Type 2 Diabetes

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Investigators sought to determine whether methylglyoxal levels are associated with cardiovascular disease in type 2 diabetes.

Clinician Perspective: Examining the Link Between Antipsychotics and Diabetes

Clinician Perspective: Examining the Link Between Antipsychotics and Diabetes

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Endocrinologist Kevin M. Pantalone, DO, and psychiatrist Christian Kohler, MD, discuss the risk associated with the use of antipsychotic medications in individuals with type 2 diabetes.

Emotional Hyper-Reactivity and Cardiometabolic Risk in Remitted Bipolar Disorder

Emotional Hyper-Reactivity and Cardiometabolic Risk in Remitted Bipolar Disorder

Patients with remitted bipolar disorder and emotional hyper-reactivity also have significantly higher levels of low-grade inflammation, hypertension, and impaired glucose metabolism, indicating a higher risk for cardiometabolic dysfunction.

Cardiovascular Mortality in Individuals With Early-, Late-Onset Prediabetes

Cardiovascular Mortality in Individuals With Early-, Late-Onset Prediabetes

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Investigators examined the frequency of cardiovascular vs noncardiovascular deaths in individuals who developed prediabetes that did not progress to diabetes.

Effect of Testosterone Replacement on Glycemic Control in Obese Men With Hypogonadism, T2D

Effect of Testosterone Replacement on Glycemic Control in Obese Men With Hypogonadism, T2D

Investigators examined the effect of testosterone replacement therapy on metabolic syndrome and vascular function in obese males with hypogonadism.

Job Strain May Raise Death Risk in Men With Cardiometabolic Disease

Job Strain May Raise Death Risk in Men With Cardiometabolic Disease

Increased mortality from job strain was greater than that from hypertension, obesity, physical inactivity, and high alcohol intake.

CVD Risk Up Even in Metabolically Healthy Obese Women

CVD Risk Up Even in Metabolically Healthy Obese Women

Women with metabolically unhealthy normal-weight, overweight, obesity had a considerably higher risk for cardiovascular disease.

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