Hypertension

FDA Approves First Drug Under the Competitive Generic Therapy Pathway

FDA Approves First Drug Under the Competitive Generic Therapy Pathway

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Potassium chloride is an oral treatment indicated for the treatment and prevention of hypokalemia (low potassium blood levels) in patients who are on diuretics, and when dietary management with potassium-rich foods is insufficient or diuretic dose reduction is not possible.

High Blood Pressure Seen at School Age for Extreme Preterm Infants

High Blood Pressure Seen at School Age for Extreme Preterm Infants

Increased risk for high blood pressure and hypertension seen in both overweight and normal-weight 6- to 7-year-olds.

Kapspargo Sprinkle Available to Treat Hypertension, Angina, Heart Failure

Kapspargo Sprinkle Available to Treat Hypertension, Angina, Heart Failure

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For patients unable to swallow an intact capsule, the pellets can be sprinkled over soft food (eg, applesauce, yogurt, pudding) or given via a nasogastric (NG) tube.

Use of BP-Interfering Medications Examined Among Patients With Hypertension

Use of BP-Interfering Medications Examined Among Patients With Hypertension

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To better understand the real-world use of these agents among patients with hypertension, researchers conducted a retrospective drug utilization study using medical and prescription claims from the Marketscan database (January 2008 to December 2014).

Tool Improves Identification of Undiagnosed Hypertension

Tool Improves Identification of Undiagnosed Hypertension

Use of billing data alone shows that up to 1 in 8 hypertension cases might be undiagnosed.

Use of 2017 ACC/AHA Guidelines Would Increase Hypertension Prevalence

Use of 2017 ACC/AHA Guidelines Would Increase Hypertension Prevalence

Adoption of the 2017 American College of Cardiology/American Heart Association guidelines would label more than half of 45- to 75-year-olds as having hypertension.

Higher LV Mass Index Associated With Compromised White Matter Microstructure

Higher LV Mass Index Associated With Compromised White Matter Microstructure

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In older adults with dementia symptoms, increased left ventricle mass index was associated with compromised white matter microstructure.

Hypertension Disorders in Pregnancy: The Potential of Prophylactic Aspirin

Hypertension Disorders in Pregnancy: The Potential of Prophylactic Aspirin

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To aid in the prevention of preeclampsia, American College of Obstetricians and Gynecologists and the US Preventive Services Task Force recommend low-dose aspirin prophylaxis in patients with 1 or more high-risk factors.

Preeclampsia, Gestational Hypertension Increases CVD Risk Later in Life

Preeclampsia, Gestational Hypertension Increases CVD Risk Later in Life

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Women with preeclampsia or gestational hypertension during their first pregnancy were more likely to report increased rates of subsequent chronic hypertension, type 2 diabetes, and hypercholesterolemia compared with women who were normotensive.

Heart Meds Recalled After Discovery of Possible Carcinogenic Impurity

Heart Meds Recalled After Discovery of Possible Carcinogenic Impurity

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As valsartan is used to treat various cardiovascular conditions including heart failure and hypertension, patients should continue to take their medications until they have a replacement product,

Hypertension Risk Elevated in Blacks Through Age 55

Hypertension Risk Elevated in Blacks Through Age 55

Regardless of blood pressure levels in young adulthood, blacks have increased hypertension risk vs whites.

EHR Tools Improve Medication Reconciliation in Hypertension

EHR Tools Improve Medication Reconciliation in Hypertension

However, systolic blood pressure did not differ in the electronic health record-plus-education group vs the usual care group.

Preeclampsia With Severe Features Increases Risk for Cardiac Abnormalities

Preeclampsia With Severe Features Increases Risk for Cardiac Abnormalities

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Women with preeclampsia with severe features had increased right ventricular systolic pressure and decreased global right ventricular longitudinal systolic strain.

Calcium Channel Blocker May Benefit Patients With Type 1 Diabetes

Calcium Channel Blocker May Benefit Patients With Type 1 Diabetes

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For this study, researchers conducted a randomized, double-blind, placebo-controlled Phase 2 trial (N=24) to assess the efficacy and safety of adding oral verapamil for 12 months to a standard insulin regimen in adults with recent-onset type 1 diabetes (age range: 18 to 45 years).

Pediatric Hypertension Prevalence Increased With New Definitions

Pediatric Hypertension Prevalence Increased With New Definitions

Incorporation of new pediatric definitions increased the prevalence of hypertension in high-risk youth.

Hydralazine-Induced Hepatotoxicity Described in Case Report

Hydralazine-Induced Hepatotoxicity Described in Case Report

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Symptoms in patients with short latency include fever, rash, and eosinophilia.

Binge Drinking Linked to Increased Systolic Blood Pressure in Men

Binge Drinking Linked to Increased Systolic Blood Pressure in Men

The relative risk for hypertension increased with any drinking in men without hypertension.

Empagliflozin Reduces Nephropathy Risk Irrespective of Blood Pressure Control

Empagliflozin Reduces Nephropathy Risk Irrespective of Blood Pressure Control

Investigators examined renal outcomes when controlling cardiovascular risk factors, such as blood pressure, LDL-C, and HbA1c.

No Causal Effect of Vitamin D on Gestational Hypertension, Preeclampsia

No Causal Effect of Vitamin D on Gestational Hypertension, Preeclampsia

There was no strong evidence of a linear effect for 25-hydroxyvitamin D on the risk of gestational hypertension or preeclampsia in the one-sample mendelian randomization analysis.

Higher Blood Pressure at Mid-Life Increases Dementia Risk

Higher Blood Pressure at Mid-Life Increases Dementia Risk

The risk for dementia may increase with blood pressure ≥130 mm Hg in 50-year-olds.

Disparities for Recurrent Hemorrhagic Stroke Risk Unexplained

Disparities for Recurrent Hemorrhagic Stroke Risk Unexplained

Higher risk for second hemorrhagic stroke in blacks and Hispanics is not fully explained by hypertension severity.

Under New Guidelines, More Stroke Survivors With Hypertension Diagnosis

Under New Guidelines, More Stroke Survivors With Hypertension Diagnosis

More stroke survivors are not within the new recommended blood pressure targets compared with Joint National Committee report.

AHA: Limited Health Literacy Is Barrier to Cardiovascular Care

AHA: Limited Health Literacy Is Barrier to Cardiovascular Care

Use of Universal Precautions Toolkit recommended for improving quality of cardiovascular care.

Consensi Approved to Treat Hypertension and Osteoarthritis Pain

Consensi Approved to Treat Hypertension and Osteoarthritis Pain

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Consensi combines amlodipine besylate, a calcium-channel blocker (CCB), and celecoxib, a nonsteroidal anti-inflammatory drug (NSAID).

Annual Healthcare Expenditure Higher for Hypertension

Annual Healthcare Expenditure Higher for Hypertension

Individuals with hypertension have 2.5 times the inpatient cost, almost double outpatient cost, and almost triple the prescription medication cost.

New Hypertension Guideline Discussed for Older Adults

New Hypertension Guideline Discussed for Older Adults

Clinicians should be mindful of specific blood pressure goals proven to reduce cardiovascular disease risk.

Ideal Systolic Blood Pressure for CVD Prevention in Diabetes, Hypertension

Ideal Systolic Blood Pressure for CVD Prevention in Diabetes, Hypertension

Investigators sought to determine whether targeting systolic blood pressure of 140 mmHg in patients with type 2 diabetes would result in adverse CV outcomes.

Increase in Candidates for Treatment With 2017 Hypertension Guidelines

Increase in Candidates for Treatment With 2017 Hypertension Guidelines

The 2017 hypertension guideline was associated with an increase in proportion of adults recommended for antihypertensive treatment and an estimated decrease in cardiovascular events and deaths.

Effect of Acetyl-L-Carnitine on Blood Pressure in Type 2 Diabetes

Effect of Acetyl-L-Carnitine on Blood Pressure in Type 2 Diabetes

Investigators examined the effect of oral acetyl-L-carnitine on blood pressure, lipid and glycemic control, insulin sensitivity and kidney function in patients with hypertension and type 2 diabetes.

Maternal Exposure to Polluted Air Tied to Elevated Child BP

Maternal Exposure to Polluted Air Tied to Elevated Child BP

Overall, there was a 1.61-fold increase in risk for elevated blood pressure in children with highest vs lowest tertile of PM2.5.

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