Hypertension Latest News Archive
To investigate the association between this commonly used antihypertensive class and lung cancer, researchers conducted a population based cohort study involving 992,061 patients from the United Kingdom Clinical Practice Research Datalink.
Discord among international, organizational blood pressure guidelines have led to confusion between physicians and patients alike.
In multivariable models, associations were observed between cardiovascular risk factors and cerebrovascular morphology, as well as white matter hyperintensity count.
The use of β-blockers in the first trimester of pregnancy may not greatly increase the risk for major congenital malformations in offspring.
An association was found between increased systolic blood pressure and risk for aortic stenosis and regurgitation.
A greater proportion of patients with dysautonomia had supine hypertension compared with patients without dysautonomia.
Adding history of hypertensive disorders of pregnancy to the current cardiovascular disease (CVD) risk score does not improve CVD prediction in low-risk women.
The overall impact of intensive blood pressure control led to beneficial effects on cardiovascular outcomes across the spectrum of BMI models.
The primary outcome was an unfavorable neurologic outcome, which was defined as a modified Rankin Scale score of 3 to 6 at 3 months following randomization.
Individuals who would now be classified as having stage 1 hypertension according to the new American College of Cardiology/American Heart Association blood pressure guidelines also have an increased risk for cardiovascular events.
In July, several valsartan medications were recalled due to the detection of N-nitrosodimethylamine, an impurity classified as a probable human carcinogen.
Intensive blood pressure therapy is associated with a significantly lower risk for serious cardiovascular events in the adults with diabetes.
Mortality benefits from atorvastatin- and amlodipine-based antihypertensive treatments extend beyond 10 years of treatment.
The presence of heart disease and hypertension may contribute to advanced brain atrophy in patients with multiple sclerosis.
The risk of a mixing-up the treatments is especially high for pregnant women, says the Food and Drug Administration (FDA), as losartan is indicated to treat high blood pressure and could harm or kill a fetus.
A guideline-based approach directing pharmacological treatment to adults more likely to have CVD events may maximize absolute risk reduction of treatment.
Clinicians weigh in on appropriate blood pressure goals for a 79-year-old man with a mean blood pressure of 147/67 mm Hg.
To date, there have been no reports of any adverse events related to this recall.
New study suggests sodium intake is associated with cardiovascular disease and stroke only when mean sodium intake exceeds 5 grams per day.
Children who were born as extreme preterm infants may have a higher risk for high blood pressure and hypertension.
This case involved a 36-year-old female with bipolar disorder who presented to the emergency department (ED) with blurry vision, neck stiffness and the "worst headache of (her) life" after taking armodafinil with tranylcypromine.
Potassium chloride is an oral treatment indicated for the treatment and prevention of hypokalemia (low potassium blood levels) in patients who are on diuretics, and when dietary management with potassium-rich foods is insufficient or diuretic dose reduction is not possible.
For patients unable to swallow an intact capsule, the pellets can be sprinkled over soft food (eg, applesauce, yogurt, pudding) or given via a nasogastric (NG) tube.
To better understand the real-world use of these agents among patients with hypertension, researchers conducted a retrospective drug utilization study using medical and prescription claims from the Marketscan database (January 2008 to December 2014).
In older adults with dementia symptoms, increased left ventricle mass index was associated with compromised white matter microstructure.
Women with preeclampsia or gestational hypertension during their first pregnancy were more likely to report increased rates of subsequent chronic hypertension, type 2 diabetes, and hypercholesterolemia compared with women who were normotensive.
As valsartan is used to treat various cardiovascular conditions including heart failure and hypertension, patients should continue to take their medications until they have a replacement product,
Women with preeclampsia with severe features had increased right ventricular systolic pressure and decreased global right ventricular longitudinal systolic strain.
For this study, researchers conducted a randomized, double-blind, placebo-controlled Phase 2 trial (N=24) to assess the efficacy and safety of adding oral verapamil for 12 months to a standard insulin regimen in adults with recent-onset type 1 diabetes (age range: 18 to 45 years).
Symptoms in patients with short latency include fever, rash, and eosinophilia.
Investigators examined renal outcomes when controlling cardiovascular risk factors, such as blood pressure, LDL-C, and HbA1c.
Consensi combines amlodipine besylate, a calcium-channel blocker (CCB), and celecoxib, a nonsteroidal anti-inflammatory drug (NSAID).
Investigators sought to determine whether targeting systolic blood pressure of 140 mmHg in patients with type 2 diabetes would result in adverse CV outcomes.
Investigators examined the effect of oral acetyl-L-carnitine on blood pressure, lipid and glycemic control, insulin sensitivity and kidney function in patients with hypertension and type 2 diabetes.
The new blood pressure guidelines have increased the estimated population prevalence of children with elevated blood pressure from 11.8% to 14.2%.
An 8-item checklist was used to consider both benefits and harms in changing the definition of high blood pressure.
While smartphone app use led to increased medication adherence, corresponding drops in systolic blood pressure were not seen.
The composite significant kidney event end point was defined as the first occurrence of ≥30% decline in eGFR to an eGFR <60mL/min/1.73m2, initiation of dialysis or kidney transplant.
Investigators conducted a meta-analysis of trials that reported functional outcomes and mortality rates among patients with intracerebral hemorrhage following intensive blood pressure lowering.
The performance of a preeclampsia screening method using a combination of maternal factors and biomarkers was superior to the current NICE recommendations.
NR supplementation showed reductions in mean systolic blood pressure (SBP; mean change -3.9mmHg) and diastolic blood pressure (DBP; mean change -2.0mmHg) for all patients; these findings were not statistically significant after adjusting for multiple comparisons.
The FDA has posted a discontinuation notice for Twynsta for the treatment of hypertension as monotherapy.
Patients with persistent atrial fibrillation who received targeted therapy saw improvements in sinus rhythm as well as reductions in blood pressure, cholesterol, and weight.
The Cardiology Advisor interviewed George Bakris, MD on his thoughts regarding the ACC/AHA updated hypertension guidelines.
Aegis Sciences announced the launch of KardiAssure, a first-of-its-kind urinalysis to help healthcare providers track cardiovascular medication adherence in their patients.
Fixed-dose candesartan plus hydrochlorothiazide with rosuvastatin reduced the incidence of first stroke in patients at risk for cardiovascular disease.
The 2017 American College of Cardiology/American Heart Association guidelines for managing high blood pressure modify hypertension definitions and goals.
Beat-to-beat blood pressure variability is a novel way to predict risk for recurrent stroke and cardiovascular events.
Renin-independent aldosteronism, and possibly mineralocorticoid receptor activation increase risk for hypertension.
The FDA has approved angiotensin II intravenous infusion for hypotension in patients with septic shock.
Vascular endothelial dysfunction contribute to the development of premature arterial stiffening and hypertension in patients with type 1 diabetes.
Patients with blood pressure levels of >150/95 mm Hg may benefit from initial combination therapy of losartan and hydrochlorothiazide.
The FDA has approved aliskiren oral pellets for hypertension treatment.
The American Heart Association and American College of Cardiology have released hypertension guidelines which now classify high blood pressure as ≥130/80 mm Hg.
Patients taking antipsychotic agents, especially clozapine, should be monitored regularly for hypertension.
Comorbid hypertension may be mediated by reduced heart rate variability and spontaneous baroreflex sensitivity in patients with chronic pain.
A randomized controlled clinical trial examined whether intensive periodontal therapy decreases blood pressure in pre-hypertensive patients.
Obesity, hypertension, and circadian misalignment may all result from sleep debt.
Women with preeclampsia who received nonsteroidal anti-inflammatory drugs did not have an increased risk for postpartum hypertension.
Evolocumab is not associated with adverse cognitive effects even when low low-density lipoprotein cholesterol levels have been achieved.
Women who experience gestational hypertension are at a greater risk for future hypertension and ischemic heart disease compared with women who have preeclampsia.
Among black patients treated for hypertension, a systolic blood pressure (SBP) level of ≤120 mmHg results in no significant cognitive deficits
Women with hypertensive disorders in pregnancy are at increased risk of developing cardiovascular disease and hypertension postpartum.
The American Diabetes Association has updated its recommendations on the assessment and treatment of hypertension in individuals with diabetes.
The risk of angioedema is likely comparable between aliskiren and beta blockers.
The American Academy of Pediatrics has released updated clinical practice guidelines for the diagnosis and management of hypertension in children.
The ratio of hemodynamic markers derived from right heart catheterization can predict treatment outcomes in patients with pulmonary hypertension.
Smoking, duration of diabetes, and male sex were among several independent predictors of silent coronary artery disease in patients with asymptomatic diabetes.
The FDA has approved CaroSpir, the first oral liquid formulation of spironolactone for hypertension and heart failure treatment.
Blood pressure measurements taken within the first minute of standing from a supine position had the strongest association with adverse outcomes in orthostatic hypotension.
Patients with psoriasis have high rates of cardiometabolic comorbidities.
In women at high risk for preterm preeclampsia, low-dose aspirin treatment resulted in a lower incidence of diagnosis.
Intensive systolic blood pressure reductions may reduce the risk of cardiovascular events in patients with chronic kidney disease.
Sodium-glucose cotransporter 2 inhibitors produce an off-target effect on blood pressure in type 2 diabetes patients.
The new chemiluminescent enzyme immunoassay had strong sensitivity and specificity for detecting aldosteronism.
The American College of Cardiology, the American Heart Association, and the Heart Rhythm Society released a joint guideline on syncope management and treatment.
Greater left ventricle mass and left ventricle mass indexed to height were found in participants with a history of childhood asthma.
Mean arterial pressure in patients with peripheral artery disease decreased as a result of antihypertensive medication.
Visit-to-visit systolic blood pressure variability may be a better predictor of cardiovascular events and death than traditional risk factors.
Women with preeclampsia have up to a 6-fold risk of pregnancy-associated stroke.
Intensive systolic blood pressure treatment outcomes were similar between groups of patients with prediabetes and with normal fasting blood glucose levels.
Mortality rates in SLE-associated pulmonary arterial hypertension are higher compared to the general SLE population even-though diagnostic and treatment strategy have improved in the last 50 years.
New reports found that 70% of home blood pressure monitor readings are inaccurate.
Data from 15 randomized controlled trials were examined to determine rates of "clinically important reductions" in severe hypertension in pregnant women.
No differences were observed between pravastatin and usual care for CHD events, cause-specific deaths, stroke, cancer, and combination fatal CHD or nonfatal MI.
Significantly lower blood pressure can reduce cardiovascular disease mortality risk.
Patients with vasodilatory shock benefited from adjunctive angiotensin II therapy.
Achieving a systolic blood pressure goal of <120 mm Hg may have adverse cardiovascular effects for some patients.
Statin therapy did not show benefit in the primary prevention for all-cause mortality or coronary heart disease events in adults older than 65 years of age.
Pregnant women should be screened for preeclampsia by measuring blood pressure at each prenatal care visit.
More than 40% of adolescents were found to have prehypertension or hypertension associated with higher body mass index.
A Cochrane review examined whether or not uric acid-lowering therapies could effectively reduce hypertension.
Statin use may be effective in preventing decompensation in patients with liver cirrhosis.
A significantly higher incidence of hypertension was observed in patients with knee osteoarthritis compared with patients without osteoarthritis.
Patients with higher baseline blood pressure had higher 6-month combined cardiovascular disease incidence after adjustments.
Participants who received e-counseling had lower systolic blood pressure and pulse pressure at 12 months
The injection is the first ready-to-use sodium nitroprusside intended for immediate blood pressure reduction.
Cardiovascular event incidence was lower in patients taking angiotensin receptor blockers (ARBs) vs angiotensin-converting enzyme inhibitors (ACEi).
A mean difference of 18.7 mm Hg in 24-hour systolic blood pressure was observed in patients given the antihypertensive "quadpill."
Intensive blood pressure-lowering therapy (systolic blood pressure <120 mm Hg) was not associated with changes in gait speed or mobility in older adults.
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