Thrombosis

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Adding Aspirin to DOAC Therapy for AF/VTE Without Clear Indication Increases Bleeding Risk

This registry-based cohort study aimed to assess both the frequency of prescription of concomitant aspirin (ASA) and DOAC therapy as well as its effect on clinical outcomes in patients with AF or VTE.

Mechanism ID’d for Thrombosis After ChAdOx1 nCoV-19 Vaccine

Testing for antibodies to platelet factor 4 positive in 22 of 23 patients; treatment with platelet transfusion should be avoided.

New DOAC Users Experience Fewer Risks for Ischemic Stroke, Major Bleeding vs New Warfarin Users

Study authors assessed the effectiveness and safety of DOACs compared with warfarin in patients with valvular atrial fibrillation.

Stroke and Systemic Embolism Risk Is Highest with HFpEF Among Heart Failure Types

Study authors assessed the risk of stroke and systemic embolism in patients with atrial fibrillation and heart failure according to HF types.

High Incidence of Thrombotic Complications, Lower Mortality in the Second Wave of Patients With COVID-19

Researchers sought to assess the incidence of thrombotic complications in the second wave of patients with COVID-19, how many patients had diagnostic imaging for these complications, overall mortality, and then compared these outcomes with the first wave.

COVID19 Vaccine Is Safe Despite Reports of Deadly Clots

The AstraZeneca vaccine, developed with researchers from Oxford University, has been heavily used in Britain

Fibrin-Specific Nanogels May Improve Result in Disseminated Intravascular Coagulation

Results of a rodent model show that fibrin-specific core-shell nanogels with a tissue-type plasminogen activator warrants more study as a treatment for patients with DIC.

ASH Issues Guidance for Preventing, Treating VTE in Cancer

Recommendations are presented for the prevention and treatment of venous thromboembolism in patients with cancer.

Platelet, Neutrophil Activation Linked to Venous Thromboembolism Risk in Patients With COVID-19

Researchers analyze platelet and neutrophil activation in COVID-19 patients and its association with venous thromboembolism.

Correct Application of Clinical Prediction Rules for VTE Associated With High Efficiency, Low Failure Rate

Applying clinical prediction rules correctly when treating patients with venous thromboembolism in primary care was found to be associated with low failure rate.