HealthDay News — There are heterogeneous associations between the level of alcohol consumption and initial presentation of cardiovascular disease, according to a study published online in The BMJ.

Steven Bell, PhD, from the University of Cambridge in the United Kingdom, and colleagues examined the correlation between alcohol consumption and cardiovascular disease in a population-based cohort study of linked electronic health records. Data were included for 1,937,360 adults aged ≥30 years.

The researchers found that 114,859 individuals received an incident cardiovascular diagnosis during a median follow-up of 6 years. There was an association for non-drinking with increased risk of unstable angina, myocardial infarction, unheralded coronary death, heart failure, ischemic stroke, peripheral arterial disease, and abdominal aortic aneurysm (hazard ratios [HR]: 1.33, 1.32, 1.56, 1.24, 1.12, 1.22, and 1.32, respectively), compared with moderate drinking. Heavy drinking that exceeded guidelines correlated with an increased risk of presenting with unheralded coronary death, heart failure, cardiac arrest, transient ischemic attack, ischemic stroke, intracerebral hemorrhage, and peripheral arterial disease (HR: 1.21, 1.22, 1.50, 1.11, 1.33, 1.37, and 1.35, respectively), and with reduced risks of myocardial infarction (HR: 0.88; 95 percent confidence interval, 0.79 to 1.00) or stable angina (HR: 0.93; 95% CI, 0.86-1.00).

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“This has implications for counselling patients, public health communication, and clinical research, suggesting a more nuanced approach to the role of alcohol in prevention of cardiovascular disease is necessary,” the authors write.

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  1. Bell S, Daskalopoulou M, Rapsomaniki E, et al. Association between clinically recorded alcohol consumption and initial presentation of 12 cardiovascular diseases: population based cohort study using linked health records [published online March 22, 2017]. BMJ. doi: 10.1136/bmj.j909
  2. Mukamal K. Alcohol and cardiovascular disease [published online March 22, 2017]. BMJ. doi: 10.1136/bmj.j1340