HealthDay News – Cardiac arrest patients who receive epinephrine within 5 minutes are more likely to survive than those who don’t receive the drug within that time frame, according to findings published online in Circulation.

Researchers analyzed outcomes among 103,932 patients with cardiac arrest at 548 hospitals across the United States.

Survival rates were 12.9% among patients who received epinephrine within 5 minutes of cardiac arrest. This compared to 10.8% among those who received the drug after 5 minutes. The researchers also found that delays in receiving epinephrine led to poorer recovery in patients, and that hospitals that dealt with larger numbers of cardiac arrests tended to administer epinephrine sooner than those with fewer cases.


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“Further studies are needed to determine if improving hospital performance on time to epinephrine administration, especially at hospitals with poor performance on this metric will lead to improved outcomes,” the authors wrote.

Reference

Khera R, Chan PS, Donnino MW, et al; for the American Heart Association’s Get With The Guidelines-Resuscitation Investigators. Hospital variation in time to epinephrine for non-shockable in-hospital cardiac arrest [Published online December 1, 2016]. Circulation. doi:10.1161/CIRCULATIONAHA.116.025459.