HealthDay News – Some clinical departments tend to undertreat when prescribing statins, according to a study published in the February issue of the Journal of Clinical Pharmacy and Therapeutics.

Hun-Sung Kim, MD, PhD, from the Catholic University of Korea in Seoul, and colleagues examined the department-specific disparities and achievement rates for low-density lipoprotein cholesterol (LDL-C) targets based on each department’s prescription patterns for 31 718 patients who had been prescribed a statin. Based on the National Cholesterol Education Program-Adult Treatment Panel III guidelines, patients were classified into high-risk (target LDL-C <100 mg/dL) and moderate-risk (target LDL-C <130 mg/dL) groups.

The researchers found that statins were most commonly prescribed in cardiology and endocrinology departments (32% and 26.6%, respectively). Target LDL-C levels were achieved by 70% of high-risk patients in the cardiology, endocrinology, and cardiac surgery departments, while 79.2% of the moderate-risk group achieved target levels. In most other departments, the target achievement rates were below 70% for high-risk patients. The likelihood of achieving target LDL-C levels was higher for departments that prescribed a greater number of high- or intermediate-potency statins. There was a significant positive relationship for the group that achieved their target LDL-C levels, from low to high potency.

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“To reach to the target LDL-C levels, physicians must overcome their tendency to undertreat with statins,” the authors wrote.


Kim H.-S, Kim H, Lee H, et al. Analysis and comparison of statin prescription patterns and outcomes according to clinical department. J Clin Pharm Ther. 2016;41(1):70-77. DOI: 10.1111/jcpt.12350.