Dyslipidemia

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Dyslipidemia

Statins Found to Be Safe and Effective for the Treatment of Children With Familial Hypercholesterolemia

Pediatricians should be familiar with familial hypercholesterolemia and prescribe statins to treat this disorder.

Dyslipidemia

Leveraging Machine Learning to Identify Familial Hypercholesterolemia

A machine learning model trained to identify patients with familial hypercholesterolemia using large deidentified healthcare encounter data was found to be successful.

Vascular Medicine

Risk for Large Vessel Peripheral Arterial Occlusion in COVID-19 With Elevated Inflammatory Markers

Patients with COVID-19 and comorbidities who present with elevated levels of inflammatory markers and D-dimer may have an increased risk for large vessel peripheral arterial occlusion.

Dyslipidemia

Combined Hyperlipidemia Found to Be Genetically Similar to Isolated Hypertriglyceridemia

Combined hyperlipidemia was found to be similar genetically to isolated hypertriglyceridemia.

Dyslipidemia

Evinacumab Lowers LDL Cholesterol in Refractory Hypercholesterolemia

In this phase 2 trial, patients with hypercholesterolemia and clinical atherosclerotic cardiovascular disease were recruited from 85 sites across 20 countries.

Heart Failure

Metformin Treatment in Patients With T2DM at Risk for Heart Failure

Patients with type 2 diabetes mellitus at risk for heart failure treated with metformin may have reduced deterioration of LV filling pressures and myocardial relaxation.

Dyslipidemia

Remnant Cholesterol Concentration an Independent Predictor of Poor Cardiovascular Outcomes

Poor cardiovascular outcomes are more likely in patients with elevated remnant cholesterol or triglycerides.

Dyslipidemia

Statin Use for Primary Prevention of CVD Lower for Sexual Minorities

The lesbian, gay, and bisexual (LGB) population has a lower prevalence of statin use for primary prevention of cardiovascular disease.

Stroke

LDL-C Polygenic Risk Score and ASCVD in Monogenic Familial Hypercholesterolemia

Elevated LDL-C polygenic scores associated with higher LDL-C levels and increased risk for ASCVD in patients with monogenic familial hypercholesterolemia.

Dyslipidemia

Genetic Background and the Response to Lipid-Lowering Therapy in Familial Hypercholesterolemia

Associations between pathogenic variant positivity and 4-single nucleotide polymorphism score were established in patients with familial hypercholesterolemia in response to lipid-lowering therapy.