Cardiometabolic Effects of Gender-Affirming Hormone Therapy in Transgender Youth
Transgender youth on gender-affirming hormone therapy have differences in their percent fat and lean mass compared with cisgender youth.
Dyslipidemia
DYSLIPIDEMIA
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Tool Developed to Assess Long-Term CVD Risk, Benefit of Lipid-Lowering Intervention
The blood levels of non-high density lipoprotein cholesterol were found to have a strong association with the long-term risk for a cardiovascular disease event.
Presence of Hyperlipidemia May Lower Mortality After MI, ADHF
The presence of hyperlipidemia following hospitalization for acute myocardial infarction or acute decompensated heart failure may be associated with reduced mortality.
Dose-Dependent Reduction of Lipoprotein(a) With APO(a)-LRx
The hepatocyte-directed antisense oligonucleotide AKCEA-APO(a)-LRx was found to lower in a dose-dependent manner lipoprotein(a) levels in patients with elevated lipoprotein(a) levels and established cardiovascular disease.
Time-Restricted Eating May Improve Metabolic Syndrome
Reducing the daily eating window from ≥14 hours to a self-selected 10-hour window may lead to weight loss and a decrease in metabolic risk factors.
HDL Cholesterol Can Be Used to Monitor Triglycerides, Remnant Cholesterol
Low HDL-C may be used to monitor long-term average triglycerides and remnant cholesterol levels, similar to how high hemoglobin A1c is used to monitor long-term elevated glucose levels.
Pharmacist-Led Interventions Cut Cardiovascular Risk Factors
Pharmacist-led interventions in general practice can significantly reduce medical risk factors associated with cardiovascular events.
Statins May Increase Risk for Diabetes, Skin Infections
The study demonstrated a mechanism of statins can induce onset of diabetes.
Twice-Yearly Dosing of Inclisiran Provides Significant LDL-C Lowering
Twice-yearly dosing with inclisiran sodium resulted in significant lowering of low-density lipoprotein cholesterol.
Clinical Features Can Differentiate FCS From Severe Hypertriglyceridemia
Several clinical features can be accurate in differentiating between familial chylomicronemia syndrome and severe hypertriglyceridemia.
Residual Hypertriglyceridemia With Statin Treatment Common in Diabetes
One-third of patients with diabetes and HTG overall and approximately 40% of statin users were found to be at high long-term cardiovascular risk.
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