Dyslipidemia

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Dyslipidemia

Tofacitinib Therapy Did Not Alter Lipid Levels Among Patients With Colitis

Investigators evaluated data on lipid levels and cardiovascular events in addition to recommendations for managing lipid levels during tofacitinib treatment in patients with ulcerative colitis, according to up-to-date expert guidelines.

General Cardiology

Cardiometabolic Disease Risk Factors Among Drug Users

Researchers used data from the National Health and Nutrition Examination Survey 2009-2018 to assess the impact of drug and alcohol use on cardiometabolic disease risk factors.

Dyslipidemia

HDL Cholesterol Efflux May Be Impaired in Severe Short-Term Hypothyroidism

High-density lipoprotein cholesterol efflux capacity may be impaired in patients with severe short-term hypothyroidism.

Dyslipidemia

HDL Mimetic May Not Benefit Patients With Familial Hypoalphalipoproteinemia

Patients with very low levels HDL-cholesterol did not have improvements in carotid wall inflammation or dimensions when treated with an HDL mimetic.

General Cardiology

Study to Examine Efficacy of Canakinumab in COVID-19 With Acute Myocardial Injury

Recruitment has begun for study examining the efficacy of canakinumab for the treatment of patients with COVID-19 and acute myocardial injury.

Dyslipidemia

Consistent LDL-C Lowering Reported With Twice-Yearly Inclisiran

The post-hoc analysis included 2 placebo-controlled phase 3 studies (ORION-10 and -11) that evaluated the efficacy and safety of inclisiran sodium in more than 2300 adult patients.

Dyslipidemia

Higher Triglyceride Levels Linked to Adverse Cardiovascular Outcomes

Researchers sought to determine whether triglyceride levels were independently associated with cardiovascular disease among patients with coronary artery disease and type 2 diabetes.

Vascular Medicine

Second-Generation Drug-Eluting Stents Fully Covering a CAA and Stenosis Lesion Found to Be Safe

The implantation of a second-generation drug-eluting stent fully covering a coronary artery aneurysm and stenosis lesion was found to be safe and effective.

Dyslipidemia

Evinacumab Found to Lower LDL-C in Homozygous Familial Hypercholesterolemia

The addition of evinacumab to stable lipid-lowering therapy was found to reduce levels of LDL-C in patients with homozygous familial hypercholesterolemia.

Dyslipidemia

Evolocumab Lowers LDL-C in Pediatric Patients With HeFH

The multicenter, double-blind, placebo-controlled HAUSER-RCT study assessed the efficacy and safety of evolocumab in 157 patients aged 10 to 17 years with HeFH.