Metabolic

Latest News

Maintaining Weight Loss Reduces Cardiovascular Risk in T2DM

Allowing weight regain as part of maintenance reduces cardiometabolic benefit for many risk factors

Addressing Hypertriglyceridemia and Cardiovascular Risk in Diabetes

There is growing evidence that the addition of triglyceride-lowering medication and lifestyle changes may be valuable in diabetes management.

Female Adolescents More Susceptible to Circadian Misalignment-Related Adiposity

Increasing evening chronotypes and social jet lag are associated with increased adiposity in adolescent girls.

Women With Cardiometabolic Risk Factors More Vulnerable to Cortical Atrophy

The effects of cardiometabolic risk factors on cortical thickness are different between men and women, as women with these risk factors are more vulnerable to cortical atrophy than men.

Higher Fat Mass Linked to Major Adverse CV Event Risk in T2DM

In patients with type 2 diabetes, higher fat mass is associated with a higher risk for major adverse cardiovascular events.

Inclisiran Benefits Patients With Familial Hypercholesterolemia and ASCVD

Inclisiran is a chemically synthesized small interfering RNA (siRNA) that targets proprotein convertase subtilisin-kexin type 9 (PCSK9) messenger RNA.

Leisure Activity May Attenuate Menopause-Related Atherogenic Changes

The menopausal transition may be a stronger determinant of serum cardiovascular risk factors than chronologic age.

More Aggressive Treatment Needed for Familial Hypercholesterolemia

Even with care in specialty clinics, LDL-C persists above target levels in more than half of patients with familial hypercholesterolemia.

Lipid-Lowering Therapy May Reduce Need for AVR in Mild Aortic Stenosis

Investigators examined whether pretreatment low-density lipoprotein cholesterol levels and aortic stenosis severity affect lipid-lowering therapy to decrease aortic valve replacement.

Elevated Triglycerides Linked to Worse CV and Health Economic Outcomes

Researchers used using observational administrative claims data from the Optum Research Database to retrospectively examine the real-world effect of elevated triglyceride levels on cardiovascular outcomes and medical cost.