HealthDay News – The use of transcatheter aortic valve replacement (TAVR) increased in Germany from 2007 to 2013, with a moderate concomitant reduction in surgical aortic valve replacement (SAVR), according to a study published in the December 17 issue of the New England Journal of Medicine.

Jochen Reinöhl, MD, from the University of Freiburg in Germany, and colleagues analyzed data on characteristics of patients and in-hospital outcomes for isolated TAVR and SAVR procedures. Data were included for 32 581 TAVR and 55 992 SAVR procedures performed in Germany from 2007 to 2013.

The researchers observed an increase in the number of TAVR procedures, from 144 in 2007 to 9147 in 2014, and a slight decrease in the number of SAVR procedures, from 8622 to 7048. Patients undergoing TAVR were older and at higher preoperative risk than those undergoing SAVR. In both groups there were decreases in in-hospital mortality from 2007 to 2013 (TAVR: from 13.2% to 5.4%; SAVR: from 3.8% to 2.2%). There were also declines in the incidences of stroke, bleeding, and pacemaker implantation, but not acute kidney injury.


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“The use of TAVR increased markedly in Germany between 2007 and 2013; the concomitant reduction in the use of [SAVR] was moderate,” the authors wrote. “In-hospital mortality decreased in both groups but to a greater extent among patients undergoing TAVR.”

Reference

Reinöhl J, Kaier K, Reinecke H, et al. Effect of availability of transcatheter aortic valve replacement on clinical practice. N Engl J Med. 2015;373:2438-2447. doi: 10.1056/NEJMoa1500893.