HealthDay News – A regional system of care seems beneficial for patients undergoing transcatheter aortic valve replacement (TAVR), according to a study published in the December 28 issue of JACC: Cardiovascular Interventions.

Dion Stub, MBBS, PhD, from St. Paul’s Hospital in Vancouver, Canada, and colleagues implemented a regional system of care for patients undergoing TAVR in British Columbia, Canada, in a prospective observational cohort study involving 583 patients. Regionalization of care involved a centrally coordinated, funded, and evaluated program, which was led by a medical director and a multidisciplinary advisory team that oversaw planning, access to care, and quality of outcomes. On the basis of consensus provincial indications, heart teams performed risk-stratified case selection for transfemoral TAVR. Referrals for lower volume and more complicated procedures were concentrated at a single site.

The researchers found that transfemoral access and non-transfemoral access was performed in 85.6% and 14.4% of cases, respectively. In 7.4% of patients, transcatheter valve-in-valve procedures were performed for failed bioprosthetic valves. Overall, 66.2% and 32.4% of patients had a balloon-expandable and self-expanding valve inserted, respectively. The all-cause 30-day mortality was 3.5%; 3.1% and 1.9% of patients experienced all-cause in-hospital mortality and disabling stroke, respectively. The median length of stay was 3 days; most patients (92.8%) were discharged home.

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“This experience demonstrates the potential benefits of a regional system of care for TAVR,” the authors wrote.

Disclosures: Several authors disclosed financial ties to the medical device industry.


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  2. Stub D, Lauck S, Lee M, et al. Regional systems of care to optimize outcomes in patients undergoing transcatheter aortic valve replacement. JACC Cardiol Interv. 2015;8(15):1944-1951. doi:10.1016.j.jcin.2015.09.017.