HealthDay News — Physical activity, but not weight loss, is associated with improved survival in coronary heart disease (CHD), according to a study published in the Journal of the American College of Cardiology.

Trine Moholdt, PhD, from the Norwegian University of Science and Technology in Trondheim, and colleagues studied 3307 individuals with CHD and examined the hazard ratio (HR) for all-cause and cardiovascular disease (CVD) mortality, calculated according to changes in body mass index and physical activity.

The researchers identified 1493 deaths during 30 years of follow-up. There was a correlation for weight loss with increased all-cause mortality (adjusted HR, 1.3; 95% CI, 1.12-1.50).

There was no correlation for weight gain with increased mortality (adjusted HR, 0.97; 95% CI, 0.87-1.09). Increased risk in association with weight loss was limited to those who were normal weight at baseline (adjusted HR, 1.38; 95% CI, 1.11-1.72). 

Compared with participants who were inactive over time, the risk for all-cause mortality was lower for those who maintained low physical activity (adjusted HR, 0.81; 95% CI, 0.67-0.97) or high physical activity (adjusted HR, 0.64; 95% CI, 0.50-0.83). Similar associations were seen for CVD mortality.

“Increased attention should be placed on strategies to increase physical activity in secondary prevention of CHD,” the authors wrote.

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