In patients with acute coronary syndrome, the early in-hospital addition of evolocumab to high-dose statin therapy was found to be safe, well tolerated, and efficacious in reducing low-density lipoprotein cholesterol levels.
Among patients with STEMI and multivessel disease, the benefit of complete revascularization over culprit-lesion only PCI was consistent irrespective of the investigator-determined timing of nonculprit lesion intervention.
Further studies are required to establish the predictive value of fragmented QRS detail characteristics for ventricular tachyarrhythmias in patients with acute myocardial infarction.
The frequency of coronary artery disease in patients who are obese was found to be lower than predicted by physicians.
Patients within a well-organized, high-volume, urban ST-segment elevation myocardial infarction network were found to have comparable management and 1-year outcomes when admitted in a primary percutaneous coronary intervention center during on-hours or off-hours.
Patients admitted to the hospital for myocardial infarction with a known diagnosis of obstructive sleep apnea were found to have improved in-hospital mortality.
Fractional flow reserve derived from coronary computed tomography angiography and cardiac magnetic resonance stress perfusion imaging may provide comparable diagnostic accuracy for predicting coronary revascularization in patients with stable chest pain and obstructive coronary artery disease.
The efficacy of melatonin, which has shown a prophylactic antidepressant effect in breast cancer, was explored given the prevalence of depressive symptoms after ACS.
Compared with current standard of care, implantation of a device for intracardiac ST-segment monitoring and alerting in people who are at high risk for recurrent ACS resulted in a significant decrease in median pre-hospital delay.
Use of sex-specific thresholds identified 5 times more additional women than men with myocardial injury.