Dyslipidemia Risk Increased Among Individuals With Higher Socioeconomic Status

Rates of dyslipidemia were observed to increase with higher socioeconomic status (SES), despite lower rates of obesity and diabetes, according to results of a study presented at the National Lipid Association Scientific Sessions, from June 2nd through 5th, in Scottsdale, AZ.

SES, according to ZIP code, may have important implications for access to healthcare and dietary options. Investigators from Memorial Healthcare System in Florida sought to evaluate the relationship between SES and dyslipidemia in the United States. Data were sourced from the 2016 to 2018 Nationwide Inpatient Sample. Univariate and multivariate analyses were performed to evaluate relationships.

Patients were divided into the first (n=27,090,614), second (n=23,576,000), third (n=21,133,731) and fourth (n=17,468,777) SES quartiles, with the first quartile having the lowest SES. The first quartile, compared with the fourth, was younger (aged mean 56.3 vs 59.5 years) and associated with higher rates of hypertension (34.8% vs 33.7%), diabetes (29.8% vs 21.8%; P <.001), and obesity (17.6% vs 14.3%; P <.001), but lower rates of dyslipidemia (28.5% vs 32.0%; P <.001).

Compared with the first quartile, the second (odds ratio [OR], 1.06; 95% CI, 1.05-1.06; P <.0001), third (OR, 1.10; 95% CI, 1.10-1.10; P <.0001), and fourth (OR, 1.12; 95% CI, 1.12-1.12; P <.0001) SES quartiles were associated with increased risk for dyslipidemia.

Compared with the fourth quartile, the third (OR, 1.10; 95% CI, 1.07-1.08; P <.0001), second (OR, 1.16; 95% CI, 1.15-1.16; P <.0001), and first (OR, 1.19; 95% CI, 1.18-1.20; P <.0001) SES quartiles were associated with increased risk for coronary heart disease among the subset of patients with dyslipidemia.

Similarly, the third (OR, 1.12; 95% CI, 1.10-1.15; P <.0001), second (OR, 1.20; 95% CI, 1.17-1.22; P <.0001), and first (OR, 1.26; 95% CI, 1.24-1.29; P <.0001) SES quartiles were associated with increased risk for peripheral artery disease among the subset of patients with dyslipidemia.

Stroke in dyslipidemia was associated with the fourth (OR, 1.04; 95% CI, 1.03-1.05; P <.0001) and third (OR, 1.02; 95% CI, 1.01-1.03; P =.001) SES quartiles.

This study found that dyslipidemia was increased among individuals with higher SES, despite lower incidences of obesity and diabetes. Among individuals who developed dyslipidemia, coronary heart disease and peripheral artery disease rates were higher among individuals with low SES and stroke risk was increased among individuals with high SES.

Disclosure: Multiple authors declared affiliations with industry. Please refer to the original article for a full list of disclosures.

Reference

Park K, Konindala N, Aung P.  Socioeconomic Disparities in Dyslipidemia and Associated Complications. Presented at: National Lipid Association Scientific Sessions; June 2-5, 2022; Scottsdale, AZ. Abstract #64.