Heart Failure

Catheter ablation of atrial fibrillation in heart failure reduces mortality and hospitalization: The CASTLE-AF trial

Compared with medical therapy alone, catheter ablation of atrial fibrillation in patients with heart failure reduced the risk for all-cause mortality and hospitalization.

ICD placement in CKD patients increases hospitalizations without survival benefit

Implantable cardioverter defibrillator placement in patients with chronic kidney disease was associated with increased risk for heart failure-related and any-cause hospitalization.

Clinical Challenge: Upper Respiratory Infection 1 Year After Heart Transplant

Clinical Challenge: Upper Respiratory Infection 1 Year After Heart Transplant

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A middle-aged woman who received a heart transplant 1 year ago presents with mild fever and generalized weakness.

Noncompaction Cardiomyopathy Care May Be Informed by Genetics

Noncompaction Cardiomyopathy Care May Be Informed by Genetics

The most common mutations found in genetic noncompaction cardiomyopathy were MYH7, MYBPC3, and TTN mutations.

Poor Outcomes in HFpEF With Low Systolic Blood Pressure

Poor Outcomes in HFpEF With Low Systolic Blood Pressure

Patients with heart failure with preserved ejection fraction had poor outcomes when they had a systolic blood pressure <120 mm Hg.

LV Diastolic, Systolic Function Drops With Extreme Caloric Restriction

LV Diastolic, Systolic Function Drops With Extreme Caloric Restriction

Very low-calorie diets can cause transient deterioration in heart function.

Heart Failure Guideline Adherence in Hospitals

Heart Failure Guideline Adherence in Hospitals

Hospital adherence to heart failure guidelines might be the best quality measure.

A 35-Year-Old Pregnant Woman Presents With Progressive Dyspnea and Palpitations

A 35-Year-Old Pregnant Woman Presents With Progressive Dyspnea and Palpitations

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A 35-year-old pregnant woman presents to the emergency department with progressive dyspnea and palpitations that have worsened during the last 3 weeks.

Atrial Fibrillation With Heart Failure: Better Outcomes With Ablation

Atrial Fibrillation With Heart Failure: Better Outcomes With Ablation

Catheter ablation was associated with a significant reduction in a composite end point of death from any cause or hospitalization for worsening heart failure in patients with atrial fibrillation.

Dyspnea at Rest in a Man With Asthma, Hypertension, and Hyperlipidemia

Dyspnea at Rest in a Man With Asthma, Hypertension, and Hyperlipidemia

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A middle-aged man with asthma, hypertension, and hyperlipidemia presents to the ED with dyspnea at rest and electrocardiogram findings suggest a prior myocardial infarction.

A 57-Year-Old Man With Heart Failure and Recurrent Hospitalizations

A 57-Year-Old Man With Heart Failure and Recurrent Hospitalizations

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A 57-year-old black man with ischemic cardiomyopathy presents with low blood pressure and dyspnea on exertion.

Effect of Left Bundle Branch Block on LV Function

Effect of Left Bundle Branch Block on LV Function

Left bundle branch block is associated with a smaller degree of left ventricular ejection fraction improvement.

Higher Rates of Hearing Loss Found in Heart Failure

Higher Rates of Hearing Loss Found in Heart Failure

Nearly three-quarters of patients aged 70 years or older with heart failure have hearing loss.

Biomarkers May Guide Congestive Heart Failure Medication Titration

Biomarkers May Guide Congestive Heart Failure Medication Titration

Mortality and hospitalization rates may improve in patients with heart failure when using biomarkers to identify patients for up-titration of medications.

High-Sensitivity Cardiac Troponin as a Predictor for Incident Heart Failure

High-Sensitivity Cardiac Troponin as a Predictor for Incident Heart Failure

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High-sensitivity cardiac troponin is associated with incident heart failure.

Outcomes after left ventricular assist device implantation significantly worse for those with end-stage renal disease

Patients with end-stage renal disease (ESRD) have significantly worse survival outcomes following left ventricular assist device (LVAD) implantation compared to recipients without ESRD.

Brain Dysfunction May Occur After Acute MI and Heart Failure

Brain Dysfunction May Occur After Acute MI and Heart Failure

Brain dysfunction may occur after acute myocardial infarction and heart failure.

Global Pulmonary Vascular Remodeling and Pulmonary Hypertension in Heart Failure

Global Pulmonary Vascular Remodeling and Pulmonary Hypertension in Heart Failure

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Researchers discovered an association between global pulmonary vascular remodeling and pulmonary hypertension in patients with heart failure.

Accuracy of Heart Failure Status Assessed by Wearable Seismocardiography

Accuracy of Heart Failure Status Assessed by Wearable Seismocardiography

Wearable technology that records cardiac function, along with machine learning algorithms, can assess compensated and decompensated heart failure states.

Effects of High-Intensity Exercise Training in Previously Sedentary Adults

Effects of High-Intensity Exercise Training in Previously Sedentary Adults

Two years of high-intensity exercise training is associated with improved maximal oxygen uptake and reduced cardiac stiffness in previously sedentary healthy middle-aged adults.

ACC Releases Decision Pathway on Heart Failure With Reduced Ejection Fraction

ACC Releases Decision Pathway on Heart Failure With Reduced Ejection Fraction

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The American College of Cardiology released a decision pathway addressing 10 pivotal issues in heart failure with reduced ejection fraction.

Survival in Aortic Stenosis May Be Predicted by LVEF

Survival in Aortic Stenosis May Be Predicted by LVEF

For patients with severe aortic stenosis, left ventricular ejection fraction <60% is associated with impaired survival.

Silent MI Associated With Increased Risk of Heart Failure

Silent MI Associated With Increased Risk of Heart Failure

Silent myocardial infarction is associated with an increased long-term risk of heart failure.

Antibiotics Not Effective in a 44-Year-Old Man With Flu-Like Symptoms

Antibiotics Not Effective in a 44-Year-Old Man With Flu-Like Symptoms

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A middle-aged man with no significant medical history presents with flu-like symptoms unresponsive to antibiotics.

Clinical Challenge: A 52-Year-Old Man With Obesity and Shortness of Breath

Clinical Challenge: A 52-Year-Old Man With Obesity and Shortness of Breath

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A 52-year-old morbidly obese man with chronic obstructive pulmonary disease complains of shortness of breath at rest and dyspnea on exertion.

A Lethargic 67-Year-Old Woman Presents With Shortness of Breath

A Lethargic 67-Year-Old Woman Presents With Shortness of Breath

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A 67-year-old woman with a history of hypertension and diabetes presents to the emergency department with marked shortness of breath.

 Novel, Subcutaneous Furosemide Formulation May Benefit Worsening Heart Failure

Novel, Subcutaneous Furosemide Formulation May Benefit Worsening Heart Failure

In outpatients with worsening heart failure, a novel, pH-neutral furosemide formulation seems to be safe and effective.

Acute Heart Failure Survival Trends With Mediterranean Diet

Acute Heart Failure Survival Trends With Mediterranean Diet

Adherence to the Mediterranean diet does not influence long-term mortality in patients with acute heart failure.

Plasma NT-proBNP Levels Vary By Race

Plasma NT-proBNP Levels Vary By Race

Black individuals have significantly lower levels of plasma N-terminal pro-B-type natriuretic peptide, than white individuals.

Clinical Review: Treating Iron Defiency Anemia in Heart Failure

Clinical Review: Treating Iron Defiency Anemia in Heart Failure

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Case study on the best practices for treating iron deficiency in heart failure patients.

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