Heart Failure

In LVSD, Diabetes Tied to Higher Risk for Heart Failure

In LVSD, Diabetes Tied to Higher Risk for Heart Failure

Asymptomatic left ventricular systolic dysfunction patients with diabetes have higher risk for heart failure than those without.

Sacubitril/Valsartan vs Enalapril for Physical Activity Improvement in HFrEF

Sacubitril/Valsartan vs Enalapril for Physical Activity Improvement in HFrEF

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Sacubitril/valsartan was associated with greater improvements in physical and social activities in patients with heart failure with reduced ejection fraction than enalapril.

Social Worker-Led Intervention Beneficial in Heart Failure

Social Worker-Led Intervention Beneficial in Heart Failure

Palliative care intervention may increase the likelihood of revising prognostic assessment in line with physician's.

Pulmonary hypertension in heart failure with preserved ejection fraction is associated with mortality

Pulmonary hypertension associated with heart failure with preserved ejection fraction (PH-HFpEF) is common in patients undergoing right heart catheterization. Transpulmonary gradient, pulmonary vascular resistance, and diastolic pulmonary gradient are predictors of mortality and cardiac hospitalizations in PH-HFpEF.

Cigarette Smoking a Risk Factor for Heart Failure in Blacks

Cigarette Smoking a Risk Factor for Heart Failure in Blacks

Current smoking linked to higher mean left ventricular mass index and lower mean left ventricular circumferential strain.

Sacubitril/Valsartan May Help Preserve Kidney Function in Patients With HFrEF

Sacubitril/Valsartan May Help Preserve Kidney Function in Patients With HFrEF

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Compared with the enalapril-treated group, those treated with sacubitril/valsartan were found to have significantly slower kidney decline (-1.3 vs -1.8mL/min/1.73m2 per year; P<0.0001).

No Higher Cancer Risk Seen for Heart Failure Patients

No Higher Cancer Risk Seen for Heart Failure Patients

After a median 20 years of follow-up, heart failure not associated with cancer incidence.

Change in BMI During Puberty Tied to Later Heart Failure Risk

Change in BMI During Puberty Tied to Later Heart Failure Risk

However, childhood BMI not independently associated with risk for heart failure.

ACC and AHA Release 2018 Quality Measures for Cardiac Rehabilitation

ACC and AHA Release 2018 Quality Measures for Cardiac Rehabilitation

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New Class 1 recommendations involve the referral of inpatients and outpatients to cardiac rehabilitation programs that include exercise training.

Elamipretide Granted Orphan Drug Status for Barth Syndrome

Elamipretide Granted Orphan Drug Status for Barth Syndrome

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The TAZPOWER study is a randomized, double-blind, placebo-controlled Phase 2/3 crossover study evaluating the safety and efficacy of elamipretide (daily subcutaneous injections) in 12 male patients (aged ≥12 years) with genetically-confirmed Barth syndrome.

High-Intensity Exercise Harmful in Arrhythmogenic Cardiomyopathy

High-Intensity Exercise Harmful in Arrhythmogenic Cardiomyopathy

High-intensity exercise was an independent marker for ventricular arrhythmia, regardless of exercise duration.

Entresto Significantly Improves Physical, Social Activity in Heart Failure Patients

Entresto Significantly Improves Physical, Social Activity in Heart Failure Patients

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Entresto may improve limitations in physical and social activities in patients with heart failure.

Oral Tx for Transthyretin Cardiomyopathy Meets Primary Endpoint in Study

Oral Tx for Transthyretin Cardiomyopathy Meets Primary Endpoint in Study

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Although they acknowledge the preliminary data is subject to further analysis, they say it demonstrates a statistically significant reduction in the combination of all-cause mortality and frequency of cardiovascular-related hospitalizations compared to placebo at 30 months.

Impaired LV Response During Exercise in Preterm-Born Adults

Impaired LV Response During Exercise in Preterm-Born Adults

With greater exercise intensity, ejection fraction lowered in preterm-born than term-born young adults.

Pulmonary Hypertension With HFpEF: Hemodynamic Markers Predict Mortality, Hospitalization

Pulmonary Hypertension With HFpEF: Hemodynamic Markers Predict Mortality, Hospitalization

Transpulmonary gradient, pulmonary vascular resistance, and diastolic pulmonary gradient are associated with mortality in patients with pulmonary hypertension and heart failure with preserved ejection fraction.

The Connection Between Cardiovascular Disease and Sleep Apnea: An Expert Interview

The Connection Between Cardiovascular Disease and Sleep Apnea: An Expert Interview

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To examine the link between cardiovascular disease and sleep apnea, The Cardiology Advisor spoke with cardiologist Seth S. Martin, MD, MHS, FACC, FAHA and sleep specialist Rachel Marie E. Salas, MD, FAAN.

Hemodynamic markers of pulmonary hypertension in heart failure with preserved ejection fraction are associated with mortality

Transpulmonary gradient, pulmonary vascular resistance, and diastolic pulmonary gradient are predictors of mortality and cardiac hospitalizations in pulmonary hypertension associated with heart failure with preserved ejection fraction.

Atrial Fibrillation Mortality May Increase With Digoxin

Atrial Fibrillation Mortality May Increase With Digoxin

Compared with patients not taking digoxin, patients with a serum digoxin concentration of ≥1.2 ng/mL had a 56% increased hazard of mortality.

Shared decision making intervention linked to improved value/treatment choice concordance in LVAD destination therapy

In this randomized, stepped-wedge control trial of patients with heart failure under consideration for mechanical circulatory support, a shared decision-making educational intervention was linked with improved patient comprehension of left ventricular assist devices and concordance of treatment choice with patient values.

Collaborative care intervention does not improve health in chronic heart failure, but alleviates depression and fatigue

Collaborative Care to Alleviate Symptoms and Adjust to Illness (CASA), a collaborative care intervention combining symptom and psychosocial care, did not improve heart failure-specific health status in chronic heart disease, compared with usual care.

Magnetically Levitated Centrifugal- vs Continuous-Flow Pump for Advanced HF

Magnetically Levitated Centrifugal- vs Continuous-Flow Pump for Advanced HF

A magnetically levitated centrifugal-flow pump was superior to a mechanical-bearing axial continuous-flow pump in patients with advanced heart failure.

Cardiovascular Outcomes of SGLT-2i vs Other Glucose-Lowering Drugs in T2D

Cardiovascular Outcomes of SGLT-2i vs Other Glucose-Lowering Drugs in T2D

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A recent study evaluated the effects of SGLT-2i and other glucose-lowering drugs on cardiovascular event outcomes in patients with type 2 diabetes from 6 countries in 3 world regions.

Automated Detection of Atrial Fibrillation Through Smartwatch Technology

Automated Detection of Atrial Fibrillation Through Smartwatch Technology

A Smartwatch band paired with an app records a 30-second single-lead rhythm strip.

Outcomes With Aspirin for Primary Prevention in Heart Failure, Type 2 Diabetes

Outcomes With Aspirin for Primary Prevention in Heart Failure, Type 2 Diabetes

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Primary prevention with aspirin may reduce all-cause mortality in patients with heart failure and type 2 diabetes.

Racial, Ethnic Differences in Cardiomyopathy Genetic Testing

Racial, Ethnic Differences in Cardiomyopathy Genetic Testing

White patients have significantly higher positive detection rates on cardiomyopathy genetic testing compared with underrepresented minorities.

LVAD Shared Decision-Making Program Demonstrates Improved Patient Knowledge

LVAD Shared Decision-Making Program Demonstrates Improved Patient Knowledge

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A shared decision-making program between patients with end-stage heart failure being considered for destination therapy left ventricular assist device and their caregivers was associated with improvement in patient knowledge.

Rheumatoid Arthritis May Increase HF Hospitalization Risk

Rheumatoid Arthritis May Increase HF Hospitalization Risk

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Rheumatoid arthritis may be associated with an increased risk for hospitalization from heart failure.

Catheter ablation of atrial fibrillation in heart failure reduces mortality and hospitalization: The CASTLE-AF trial

Compared with medical therapy alone, catheter ablation of atrial fibrillation in patients with heart failure reduced the risk for all-cause mortality and hospitalization.

ICD placement in CKD patients increases hospitalizations without survival benefit

Implantable cardioverter defibrillator placement in patients with chronic kidney disease was associated with increased risk for heart failure-related and any-cause hospitalization.

Clinical Challenge: Upper Respiratory Infection 1 Year After Heart Transplant

Clinical Challenge: Upper Respiratory Infection 1 Year After Heart Transplant

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A middle-aged woman who received a heart transplant 1 year ago presents with mild fever and generalized weakness.

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