James E. Loyd, MD, and Wendy Chung, MD, PhD, offer insight into the role of genetics in pulmonary arterial hypertension.
While ARVD/C management has greatly improved, more precautions—particularly in genetic testing and exercise—need to be taken.
No significant association was found between atrial fibrillation risk and leukocyte telomere length.
Researchers have used a gene-editing tool to repair the segment of DNA that causes hypertrophic cardiomyopathy.
A genetic predisposition to elevated serum calcium levels may increase the risk for coronary artery disease and myocardial infarction.
Individuals with 1 or 2 dominant G alleles of rs713598 in the TAS2R38 gene were 1.9 times more likely to consume sodium >2.3 g/d.
While fewer than 2% of severe hypercholesterolemia cases can be linked to familial hypercholesterolemia mutations, the latter does increase risk for coronary artery disease.
Genetic testing did not affect decisions regarding the use of clopidogrel or prasugrel in patients with acute coronary syndromes.
Patients with biallelic mutations in ALPK3 presented with severe hypertrophic and/or dilated cardiomyopathy.
Neurological disorders in perinatal LQTS patients may be caused by neurological phenotypes associated with severe cardiac phenotypes.
Shared Genetic Predisposition Between Peripartum Cardiomyopathy and Idiopathic Dilated Cardiomyopathy
Peripartum cardiomyopathy shares genetic predisposition, TTN truncating variants, with both idiopathic and familial cardiomyopathy.
Hypocretin (orexin) receptor-2, a new genetic contribution to heart failure may have promising treatment effects.
The Cardiology Advisor Articles
- A 45-Year-Old Man Presents to the ED With Shortness of Breath, Confusion
- A 56-Year-Old Man With Flu-Like Symptoms Presents With Palpitations
- Acute Coronary Syndrome Benefits From Both Antiplatelets and DOACs
- 6MWT Clinically Relevant and Appropriate Prognostic Tool for PAH
- Fear of E-Cigarette Harm Cuts Teenagers' Use
- Clopidogrel Tablets Recalled Due to Mislabeling
- Mandatory Screening for Congenital Heart Disease: Effects on Infant Mortality
- Short-Run Atrial Tachyarrhythmia Associated With Increased Stroke Risk
- Effects of High-Intensity Exercise Training in Previously Sedentary Adults
- ACC Releases Decision Pathway on Heart Failure With Reduced Ejection Fraction
- Clinical Challenge: Upper Respiratory Infection 1 Year After Heart Transplant
- Use of Multiple Antihypertensive Agents Has Increased in Hospitalizations Complicated by Preeclampsia
- Targeting Underlying Conditions May Improve Sinus Rhythm in Atrial Fibrillation
- Metformin May Preserve Beta-Cell Function in T2DM
- A 67-Year-Old Man With Shortness of Breath After the Sonoma-Napa Wildfires