James E. Loyd, MD, and Wendy Chung, MD, PhD, offer insight into the role of genetics in pulmonary arterial hypertension.
While ARVD/C management has greatly improved, more precautions—particularly in genetic testing and exercise—need to be taken.
No significant association was found between atrial fibrillation risk and leukocyte telomere length.
Researchers have used a gene-editing tool to repair the segment of DNA that causes hypertrophic cardiomyopathy.
A genetic predisposition to elevated serum calcium levels may increase the risk for coronary artery disease and myocardial infarction.
Individuals with 1 or 2 dominant G alleles of rs713598 in the TAS2R38 gene were 1.9 times more likely to consume sodium >2.3 g/d.
While fewer than 2% of severe hypercholesterolemia cases can be linked to familial hypercholesterolemia mutations, the latter does increase risk for coronary artery disease.
Genetic testing did not affect decisions regarding the use of clopidogrel or prasugrel in patients with acute coronary syndromes.
Patients with biallelic mutations in ALPK3 presented with severe hypertrophic and/or dilated cardiomyopathy.
Neurological disorders in perinatal LQTS patients may be caused by neurological phenotypes associated with severe cardiac phenotypes.
Shared Genetic Predisposition Between Peripartum Cardiomyopathy and Idiopathic Dilated Cardiomyopathy
Peripartum cardiomyopathy shares genetic predisposition, TTN truncating variants, with both idiopathic and familial cardiomyopathy.
Hypocretin (orexin) receptor-2, a new genetic contribution to heart failure may have promising treatment effects.
The Cardiology Advisor Articles
- The Mounting Evidence Against Electronic Cigarette Use
- Entresto Significantly Improves Physical, Social Activity in Heart Failure Patients
- Oxygen Therapy in Acute MI Not Associated With Clinical Benefit
- Nonpsychotic Cannabinoids in Hypertension: Benefits and Harms
- ACC and AHA Release 2018 Quality Measures for Cardiac Rehabilitation