Asthma/COPD:
Indications for: TEZSPIRE
Add-on maintenance treatment of severe asthma.
Limitations of Use:
Not for relief of acute bronchospasm or status asthmaticus.
Adult Dosage:
Give by SC inj into upper arm, thigh, or abdomen (except around the navel). Rotate inj sites. 210mg once every 4 weeks.
Children Dosage:
<12yrs: not established.
TEZSPIRE Warnings/Precautions:
Not for treating acute asthma symptoms or exacerbations. Avoid abrupt discontinuation of any corticosteroids upon Tezspire initiation; reduce gradually if appropriate. Treat pre-existing helminth infections prior to initiation; if infection develops and unresponsive to antihelmintics, discontinue Tezspire until resolves. Do not inject into tender, bruised, erythematous, or hardened skin. Pregnancy (during 3rd trimester). Nursing mothers.
TEZSPIRE Classification:
Thymic stromal lymphopoietin (TSLP) blocker.
TEZSPIRE Interactions:
Avoid concomitant live attenuated vaccines.
Adverse Reactions:
Pharyngitis, arthralgia, back pain; hypersensitivity reactions (eg, rash, allergic conjunctivitis).
Generic Drug Availability:
NO
How Supplied:
Single-dose vial, single-dose prefilled syringe—1