Migraine and headache:
Indications for EXCEDRIN MIGRAINE:
≥18yrs: 2 caplets with a glass of water; max 2 caplets/24hrs.
<18yrs: consult physician.
EXCEDRIN MIGRAINE Contraindications:
NSAID allergy. Varicella, vaccinia in children and teenagers. 3rd trimester of pregnancy.
EXCEDRIN MIGRAINE Warnings/Precautions:
Reye's syndrome. Persistent or unresponsive headache. Hypertension. Cardiovascular disease. Asthma. Peptic ulcer. GI bleeding disorders. Liver cirrhosis. Hepatic or renal impairment. Discontinue if signs/symptoms of GI bleed, migraine is not relieved or worsens after first dose, tinnitus, loss of hearing, new or unexpected symptoms develop, or severe skin reactions (eg, skin reddening, blisters, rash) occur. Headaches may worsen if used for ≥10 days per month. Elderly (≥60yrs). Pregnancy. Nursing mothers.
EXCEDRIN MIGRAINE Classification:
Analgesic + salicylate.
EXCEDRIN MIGRAINE Interactions:
May potentiate anticoagulants, hypoglycemics, methotrexate. May antagonize uricosurics. Increased risk of liver toxicity and/or GI bleed with ≥3 alcoholic drinks/day or concomitant other drugs containing acetaminophen, NSAIDs. Caution with diuretics, corticosteroids.
GI upset/bleed, prolonged bleeding time, urticaria, anaphylaxis; overdosage: salicylism, hepatoxicity.
Caplets—24, 100, 200