Edema:
Indications for: Bumetanide
Edema.
Adult Dosage:
0.5mg–2mg daily; max 10mg daily. Intermittent dosing optimal.
Children Dosage:
<18yrs: not recommended.
Bumetanide Contraindications:
Anuria. Hepatic coma. Severe electrolyte depletion.
Bumetanide Warnings/Precautions:
Hepatic cirrhosis. Ascites. Sulfonamide allergy. Progressive renal disease. Gout. Diabetes. Postsympathectomy. Monitor electrolytes, blood, liver function. Potassium supplementation may be needed. Potassium-losing nephropathy. Aldosterone excess. Discontinue if renal dysfunction progresses. Ventricular arrhythmias. Elderly. Pregnancy (Cat.C). Nursing mothers: not recommended.
Bumetanide Classification:
Diuretic (loop).
Bumetanide Interactions:
May increase digitalis, lithium toxicity. Hypokalemia with digitalis, diuretics in CHF. Alcohol, CNS depressants may increase orthostatic hypotension. Avoid probenecid, indomethacin. Ototoxicity may be potentiated with aminoglycosides.
Adverse Reactions:
Muscle cramps, dizziness, hypotension, headache, nausea, encephalopathy, ototoxicity, rash, fluid or electrolyte imbalance, hyperglycemia, hyperuricemia, blood dyscrasias.
Note:
Formerly known under the brand name Bumex.
How Supplied:
Contact supplier.