Diabetes

SGLT2 Inhibitor Use Linked to Lower Risk for Heart Failure, Death in Type 2 Diabetes

SGLT2 Inhibitor Use Linked to Lower Risk for Heart Failure, Death in Type 2 Diabetes

Regardless of presence of preexisting cardiovascular disease, SGLT2 inhibitors were associated with lower risk for death and heart failure.

Fenofibrate Improves Cholesterol Levels in Type 2 Diabetes

Fenofibrate Improves Cholesterol Levels in Type 2 Diabetes

To understand the mechanism underlying the benefit of fenofibrate on vascular complications in patients with type 2 diabetes, investigators assessed carotid intima thickness as a marker of subclinical atherosclerosis.

Plasma Methylglyoxal Levels Associated With CVD, Mortality in Type 2 Diabetes

Plasma Methylglyoxal Levels Associated With CVD, Mortality in Type 2 Diabetes

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Investigators sought to determine whether methylglyoxal levels are associated with cardiovascular disease in type 2 diabetes.

LV Strain, Hypertrophy Predict Heart Failure in Asymptomatic T2D

LV Strain, Hypertrophy Predict Heart Failure in Asymptomatic T2D

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Impaired global longitudinal strain and left ventricular hypertrophy may be predictive of incident heart failure in patients with asymptomatic type 2 diabetes.

Clinician Perspective: Examining the Link Between Antipsychotics and Diabetes

Clinician Perspective: Examining the Link Between Antipsychotics and Diabetes

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Endocrinologist Kevin M. Pantalone, DO, and psychiatrist Christian Kohler, MD, discuss the risk associated with the use of antipsychotic medications in individuals with type 2 diabetes.

Safety of DPP-IV Inhibitor, Cardiovascular Events After ACS in Type 2 Diabetes

Safety of DPP-IV Inhibitor, Cardiovascular Events After ACS in Type 2 Diabetes

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Investigators examined the time to first event composing of cardiovascular death, myocardial infarction, or stroke.

Cardiovascular Mortality in Individuals With Early-, Late-Onset Prediabetes

Cardiovascular Mortality in Individuals With Early-, Late-Onset Prediabetes

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Investigators examined the frequency of cardiovascular vs noncardiovascular deaths in individuals who developed prediabetes that did not progress to diabetes.

Effect of Testosterone Replacement on Glycemic Control in Obese Men With Hypogonadism, T2D

Effect of Testosterone Replacement on Glycemic Control in Obese Men With Hypogonadism, T2D

Investigators examined the effect of testosterone replacement therapy on metabolic syndrome and vascular function in obese males with hypogonadism.

Ideal Systolic Blood Pressure for CVD Prevention in Diabetes, Hypertension

Ideal Systolic Blood Pressure for CVD Prevention in Diabetes, Hypertension

Investigators sought to determine whether targeting systolic blood pressure of 140 mmHg in patients with type 2 diabetes would result in adverse CV outcomes.

Heart Rate Variability in Type 2 Diabetes

Heart Rate Variability in Type 2 Diabetes

Researchers conducted a systemic review and met-analysis to examine the effect of type 2 diabetes on heart rate variability.

Perioperative Cardiovascular Events More Common in Diabetes

Perioperative Cardiovascular Events More Common in Diabetes

Perioperative major adverse cardiovascular and cerebrovascular events may be more common in patients with diabetes.

Non-Nutritive Sweeteners Do Not Increase Blood Glucose Levels

Non-Nutritive Sweeteners Do Not Increase Blood Glucose Levels

Concentration of non-nutritive sweeteners decreased gradually during the course of observation after consumption.

Neprilysin Inhibition May Reduce Renal Function Deterioration in Comorbid T2D and Chronic Heart Failure

Neprilysin Inhibition May Reduce Renal Function Deterioration in Comorbid T2D and Chronic Heart Failure

This study aimed to examine the efficacy of neprilysin inhibition in treating renal disease in individuals with T2D.

Effect of Acetyl-L-Carnitine on Blood Pressure in Type 2 Diabetes

Effect of Acetyl-L-Carnitine on Blood Pressure in Type 2 Diabetes

Investigators examined the effect of oral acetyl-L-carnitine on blood pressure, lipid and glycemic control, insulin sensitivity and kidney function in patients with hypertension and type 2 diabetes.

CV Risks With Alogliptin in Type 2 Diabetes and Recent Acute Coronary Syndrome

CV Risks With Alogliptin in Type 2 Diabetes and Recent Acute Coronary Syndrome

Investigators conducted a randomized, double-blinded, placebo-trolled trial in patients with T2D after an acute coronary syndrome.

SGLT-2 inhibitors and GLP-1 agonists associated with better mortality outcomes than DPP-4 inhibitors for type 2 diabetes

SGLT-2 inhibitors or GLP-1 agonists were associated with lower mortality than DPP-4 inhibitors, placebo, or no treatment in patients with type 2 diabetes.

Biomarkers of Oxidative Stress Do Not Predict MACE in Type 2 Diabetes

Biomarkers of Oxidative Stress Do Not Predict MACE in Type 2 Diabetes

Investigators examined 6 biomarkers for predicting adverse cardiovascular outcomes in patients with type 2 diabetes.

Liraglutide May Affect Clinical Outcomes of Myocardial Infarction in Type 2 Diabetes

Liraglutide May Affect Clinical Outcomes of Myocardial Infarction in Type 2 Diabetes

Liraglutide may reduce the incidence of myocardial infarction in patients who have a high cardiovascular risk with type 2 diabetes.

Perioperative MACCEs More Common With Diabetes

Perioperative MACCEs More Common With Diabetes

Major adverse cardiovascular and cerebrovascular events with noncardiac surgery have also increased over time in patients with diabetes.

High Risk of Death After Major Diabetes-Related Amputations

High Risk of Death After Major Diabetes-Related Amputations

Risk for postoperative death varied by demographic subgroup.

Evening Preference Linked to Higher BMI in Type 2 Diabetes

Evening Preference Linked to Higher BMI in Type 2 Diabetes

Breakfast time mediates the association between morning-evening preference and body mass index in type 2 diabetes.

Aortic Stiffness, Concentric LV Remodeling Linked in T2DM

Aortic Stiffness, Concentric LV Remodeling Linked in T2DM

Aortic distensibility was independently linked to concentric left ventricular remodeling in patients with type 2 diabetes.

In LVSD, Diabetes Tied to Higher Risk for Heart Failure

In LVSD, Diabetes Tied to Higher Risk for Heart Failure

Asymptomatic left ventricular systolic dysfunction patients with diabetes have higher risk for heart failure than those without.

Social Support of Autonomy Tied to Better Glycemic Control in Diabetes

Social Support of Autonomy Tied to Better Glycemic Control in Diabetes

Findings suggest family and friends' support of autonomy also lowers diabetes distress.

Improved Outcomes With CABG vs PCI for Diabetes With LV Dysfunction

Improved Outcomes With CABG vs PCI for Diabetes With LV Dysfunction

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Aim of study was to determine whether treatment with percutaneous coronary intervention or coronary artery bypass grafting leads to improved outcomes in patients with diabetes, coronary artery disease, and left ventricular dysfunction.

Increased Risk for Mortality in People With Diabetes, CHD Taking Beta-Blockers

Increased Risk for Mortality in People With Diabetes, CHD Taking Beta-Blockers

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Further studies are needed to assess whether beta-blockers are effective in reducing mortality and coronary events in patients with diabetes receiving optimal medical treatment.

Metabolic Syndrome Common With Chronic Hepatitis B Infection

Metabolic Syndrome Common With Chronic Hepatitis B Infection

Metabolic syndrome was also associated with higher alanine aminotransferase levels longitudinally.

One-Hour Plasma Glucose Useful Predictor of Diabetic Retinopathy

One-Hour Plasma Glucose Useful Predictor of Diabetic Retinopathy

The 1-hour test is as effective as the 2-hour test in its predictive ability

Sacubitril/Valsartan May Help Preserve Kidney Function in Patients With HFrEF

Sacubitril/Valsartan May Help Preserve Kidney Function in Patients With HFrEF

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Compared with the enalapril-treated group, those treated with sacubitril/valsartan were found to have significantly slower kidney decline (-1.3 vs -1.8mL/min/1.73m2 per year; P<0.0001).

Pharmacists Can Help With Diabetes Management via Telemedicine

Pharmacists Can Help With Diabetes Management via Telemedicine

Telemedicine could provide a real-time feedback loop and allow pharmacists to help patients self-manage their diabetes.

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