Diabetes

Non-Invasive Skin Autofluorescence Measurement May Predict CVD

Non-Invasive Skin Autofluorescence Measurement May Predict CVD

Skin autofluorescence predicts incident type 2 diabetes, cardiovascular disease, and mortality in the general population

Certain SGLT2 Inhibitors Significantly Decreased ASCVD Risk in T2D

Certain SGLT2 Inhibitors Significantly Decreased ASCVD Risk in T2D

Certain SGLT2 inhibitors and glucagon-like peptide 1 receptor agonists demonstrate significant cardiovascular benefits.

Ezetimibe Plus Statin Therapy Reduces Ischemic Risk in Polyvascular Disease, T2D

Ezetimibe Plus Statin Therapy Reduces Ischemic Risk in Polyvascular Disease, T2D

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The addition of ezetimibe to simvastatin reduced ischemic risk compared with placebo, with consistent relative risk reductions in patients with and without polyvascular disease.

Skin Disease and Metabolic Syndrome: Early Warning Signs of a Greater Problem

Skin Disease and Metabolic Syndrome: Early Warning Signs of a Greater Problem

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Skin disorders, particularly those with known inflammatory mechanisms, may be considered potential early markers for the development of insulin resistance leading to metabolic syndrome, type 2 diabetes, and cardiovascular disease.

Predicting Progression of Cardiovascular Autonomic Neuropathy in Type 2 Diabetes

Predicting Progression of Cardiovascular Autonomic Neuropathy in Type 2 Diabetes

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Hyperglycemia, obesity, and hypertriglyceridemia are negatively related to cardiovascular autonomic neuropathy indices.

Liraglutide Labeling Updated With Cardiovascular Safety Data

Liraglutide Labeling Updated With Cardiovascular Safety Data

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The randomized, double-blind, placebo-controlled, parallel-group study (N=9340) evaluated the time from randomization to first occurrence of major adverse CV events (MACE) (non-fatal heart attack, non-fatal stroke, CV death) in patients treated with liraglutide 1.8mg once daily or placebo.

Metformin May Improve Vascular Health in Adolescents With Type 1 Diabetes

Metformin May Improve Vascular Health in Adolescents With Type 1 Diabetes

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Metformin improved insulin resistance regardless of baseline BMI in adolescents with type 1 diabetes.

Bariatric Surgery Reduces Macrovascular Complications in Obesity, T2D

Bariatric Surgery Reduces Macrovascular Complications in Obesity, T2D

Lower composite incidence of macrovascular events, lower incidence of coronary artery disease at 5 years

Lorcaserin Decreases Incident Diabetes Risk in Overweight Patients

Lorcaserin Decreases Incident Diabetes Risk in Overweight Patients

Lorcaserin reduces the risk for diabetes in obese or overweight patients with prediabetes or without diabetes and reduces HbA1c among those with diabetes.

LVAD in Heart Failure Linked to Improved Glycemic Control

LVAD in Heart Failure Linked to Improved Glycemic Control

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HbA1c levels following left ventricular assist device implantation were statistically significantly lower than before surgery.

Should Intensive BP Treatment Be Generalized to Adults With Diabetes?

Should Intensive BP Treatment Be Generalized to Adults With Diabetes?

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Intensive blood pressure therapy is associated with a significantly lower risk for serious cardiovascular events in the adults with diabetes.

Trends in Cardiovascular Deaths for US Adults With and Without Diabetes

Trends in Cardiovascular Deaths for US Adults With and Without Diabetes

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Investigators used data from the National Health Interview Survey and follow-up mortality data to estimate trends and disparities in CVD.

Reducing HF Hospitalization Risk: Antidiabetic Drug Classes Compared

Reducing HF Hospitalization Risk: Antidiabetic Drug Classes Compared

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The authors searched for randomized placebo-controlled trials (December 1, 2008 to November 24, 2017) involving 3 pharmacologic classes of antidiabetic medications to compare the effects of these agents on the risk of hospitalization for HF in T2DM patients.

Higher Aldosterone Levels Tied to Incident Type 2 Diabetes Risk

Higher Aldosterone Levels Tied to Incident Type 2 Diabetes Risk

Racial/ethnic differences were seen in the association of aldosterone with incident type 2 diabetes.

Widespread Statin Use Not Recommended in Old, Very Old

Widespread Statin Use Not Recommended in Old, Very Old

No benefit in healthy elderly patients; the protective effect is limited to those with type 2 diabetes aged 75 to 84 years.

WHO Issues Recommendations for T2DM Treatment Intensification

WHO Issues Recommendations for T2DM Treatment Intensification

WHO has also made recommendations for type of insulin for type 1 and type 2 diabetes in low-resource settings.

Evaluating Excess Risk for Heart Failure Hospitalization in Type 2 Diabetes

Evaluating Excess Risk for Heart Failure Hospitalization in Type 2 Diabetes

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Investigators examined the excess risk for heart failure in patients with type 2 diabetes and compared the risk with that in the general population without diabetes.

Assessing the Evidence of Aspirin for Primary Prevention in Diabetes

Assessing the Evidence of Aspirin for Primary Prevention in Diabetes

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The substantial burden of cardiovascular disease in patients with diabetes has led to the exploration of various cardiovascular disease prevention strategies, including the use of aspirin.

Low Rates of Increasing Statin Doses After MI in Diabetes

Low Rates of Increasing Statin Doses After MI in Diabetes

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Up-titration to a high-intensity statin occurred in only 37.7% of patients with diabetes after an acute myocardial infarction.

Inflammation and Endothelial Stress Associated With CV Risk in Type 2 Diabetes With Manifest CVD

Inflammation and Endothelial Stress Associated With CV Risk in Type 2 Diabetes With Manifest CVD

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The risk for cardiovascular events in patients with type 2 diabetes without manifest cardiovascular disease is primarily related to the severity of atherosclerosis.

Link Between Gestational Diabetes and Risk for CVD and Diabetes in Hispanic/Latina Population

Link Between Gestational Diabetes and Risk for CVD and Diabetes in Hispanic/Latina Population

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Investigators sought to compare cardiovascular risk and disease prevalence in the Hispanic and Latina population in the United States with and without a history of gestational diabetes.

Low Predictive Power of Biomarkers for Estimated Glomerular Filtration Rate Decline

Low Predictive Power of Biomarkers for Estimated Glomerular Filtration Rate Decline

While certain biomarkers are associated with eGFR decline in patients with type 2 diabetes, their predictive power is low.

Relationship Between HbA1c and Coronary Artery Disease

Relationship Between HbA1c and Coronary Artery Disease

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Investigators examined the relationship between HbA1c with cardiovascular disease and it's subtypes.

Death Risk Not Increased in T2DM When Risk Factors Within Target

Death Risk Not Increased in T2DM When Risk Factors Within Target

Little or no excess risk of death, MI, or stroke in patients with type 2 diabetes who had their 5 risk factor variables within target ranges.

Weight Gain After Quitting Smoking May Increase T2DM Risk

Weight Gain After Quitting Smoking May Increase T2DM Risk

However, the temporary increase in type 2 diabetes risk does not attenuate benefits on total and CVD mortality.

Casual Glucose Concentrations Predict Post-Surgical Myocardial Injury

Casual Glucose Concentrations Predict Post-Surgical Myocardial Injury

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Glucose concentration assessment before noncardiac surgery may help clinicians predict the risk for postoperative myocardial injury in patients with and without diabetes.

Single Threshold May Not Be Feasible for Gestational Diabetes

Single Threshold May Not Be Feasible for Gestational Diabetes

Diagnostic thresholds for gestational diabetes should be adapted using local populations.

Nut Intake Reduces HbA1c Among Adults With T2DM

Nut Intake Reduces HbA1c Among Adults With T2DM

A full-nut dose lowered HbA1c and estimated cholesterol levels in LDL particles of a certain diameter.

Independent Relationship Between CV Mortality, Oxidative DNA Damage in Type 2 Diabetes

Independent Relationship Between CV Mortality, Oxidative DNA Damage in Type 2 Diabetes

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This represents the prospective study confirming an independent relationship between cardiovascular mortality and oxidative DNA damage in type 2 diabetes.

Diabetes Diagnosis May Affect Health Behaviors of Family

Diabetes Diagnosis May Affect Health Behaviors of Family

Small changes in health behaviors were seen in partners of those newly diagnosed with diabetes.

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