Coronary Artery Disease in Diabetes: Disease Extent Similar in Women, Men

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There was no substantial difference in indications for coronary angiography for women vs men with type 1 diabetes.
There was no substantial difference in indications for coronary angiography for women vs men with type 1 diabetes.

HealthDay News — For patients with type 1 diabetes, the extent of coronary artery disease (CAD) is similar in women and men admitted for coronary angiography, according to a study published in Diabetes Care.

Viveca Ritsinger, from the Karolinska Institute in Sweden, and colleagues followed patients with type 1 diabetes undergoing coronary angiography from 2001 to 2013 for mortality until December 31, 2013. A total of 2776 patients (mean age, 58 years) were followed for 7.2 years.

The researchers found that there was no substantial difference in indications for coronary angiography for women and men. 

Women had somewhat less severe extent of CAD (normal angiogram, 23.5% vs 19.1%; 3-vessel and left main stem disease, 34.5% vs 40.4%; P =.002); no difference was seen in mortality (adjusted hazard ratio, 1.03; 95% CI, 0.88 to 1.2; P =.754). For the first year, the standard mortality ratio was 7.49 (95% CI, 5.73 to 9.62) and 4.58 (95% CI, 3.6 to 5.74) for women and men, respectively.

"In patients with type 1 diabetes admitted for coronary angiography, the extent of CAD was almost similar in women and men, and total long-term mortality did not differ," the authors wrote. "These data support that type 1 diabetes attenuates the cardiovascular risk difference seen in men and women in the general population."

Disclosures: Several authors disclosed financial ties to the pharmaceutical industry.

Reference

Ritsinger V, Hero C, Svensson AM, et al. Characteristics and prognosis in women and men with type 1 diabetes undergoing coronary angiography: a nationwide registry report [published online February 20, 2018]. Diabetes Care. doi:10.2337/dc17-2352

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