CHD Latest News Archive
A simple intervention may contribute to the prevention of CVD and may improve medication adherence and lifestyle modification.
Children and adolescents with metabolically healthy obesity had higher carotid intima-media thickness compared with metabolically healthy individuals who were a normal weight.
Among individuals at a high risk for cardiovascular disease, a panel of short- and long-chain acylcarnitines was significantly associated with the incidence of type 2 diabetes.
Investigators sought to determine whether cardioprotective medication after a myocardial infarction could reduce mortality rates in patients with schizophrenia.
A history of gout was associated with worse outcomes in patients with obstructive coronary artery disease.
Investigators evaluated the association between modifiable cardiovascular disease risk factors at recommended levels and white matter hyperintensities and indices of cerebrovascular structure and function.
Type 2 diabetes is an independent risk factor for sudden cardiac arrest and death in patients with coronary artery disease with preserved ejection fraction.
Higher levels of estradiol were inversely associated with carotid artery intima-media thickness progression in the early postmenopausal cohort but positively associated with it in the late postmenopausal group.
Aortic vascular inflammation is a potential precursor to early coronary artery disease in patients with psoriasis.
The findings could corroborate existing evidence on how changes in serum ACE, the renin-angiotensin system, and vascular endothelium metabolism may be linked to atherosclerosis in psoriasis.
Carotid artery plaque was predictive of mortality, with differences observed by sex and HIV serostatus.
High perivascular fat attenuation index values are important markers of increased cardiac mortality and can guide targeted prevention strategies in this patient population.
Investigators examined the relationship between HbA1c with cardiovascular disease and it's subtypes.
No Impact on Carotid Artery Intima-Media Thickness Following Cessation of Menopausal Hormone Therapy
A follow-up study from KEEPS found that cessation of menopausal hormone therapy did not change the expected trajectory of carotid artery intima-media thickness over a 3-year period.
A significantly higher rate of adverse cardiac events was observed in chronic total occlusions compared with moderate to severe coronary artery disease.
The SYNTAX score II was an independent predictor of mortality in patients with 1- and 2-vessel disease undergoing percutaneous coronary intervention.
Investigators assessed the effect of erenumab on total exercise time, time to exercise-induced angina, and ST depression in patients with stable angina.
An increase in atheroma burden and plaques with less stable features demonstrated an association with immunoglobulin E to α-Gal.
Investigators demonstrated that angina severity at baseline should be a less important aspect of the diagnostic and therapeutic algorithm.
Treatment with levothyroxine to normalize thyroid-stimulating hormone did not significantly reduce carotid intima media thickness in elderly patients with subclinical hypothyroidism.
Alcohol consumption may be inversely related to nonfatal CHD risk but positively correlated with risks for other stroke subtypes.
Researchers conducted the first systematic review and meta-analysis to assess the relationship between HBV and the risk for coronary heart disease.
Compared with standard care, noninvasive coronary artery disease screening reduced cardiac events by 27% in individuals with asymptomatic diabetes. Results justify larger, appropriately powered trials to potentially revisit current recommendations.
Myocardial infarction and coronary heart disease may be predicted by multibiomarker disease activity in patients with rheumatoid arthritis.
Patients with stable chest pain who have high-risk plaque as identified by coronary computed tomographic angiography may have a higher risk for MACE.
In an analysis of the PESA study, nearly 50% of patients without cardiovascular risk factors had subclinical atherosclerosis.
Two new indications for rivaroxaban submitted to the FDA to reduce the risk of major cardiovascular events in patients with chronic CAD and/or PAD.
The association between sleep duration and incident diabetes may be similar to the association between sleep duration and incident coronary heart disease.
Acarbose, an α-glucosidase inhibitor, decreased the incidence of diabetes in a population with impaired glucose tolerance at low risk of cardiovascular events.
No evidence shows efficacy of PCI procedures for patients with stable coronary artery disease with angina.
Restrictive spirometry pattern and reduced forced vital capacity level are associated with increased risk of arterial stiffness.
Depression may be linked to recurrent chest pain even without coronary artery disease.
Coronary artery calcium may be the best noninvasive risk marker for predicting a major cardiovascular event in patients with COPD.
Patients with severe obstructive sleep apnea may experience a decrease in carotid intima-media thickness with continuous positive airway pressure therapy.
E-cigarettes with nicotine may be linked to arterial stiffening, which can increase the risk for heart attack and stroke.
When compared with other imaging modalities, positron emission tomography offers the greatest diagnostic accuracy for coronary artery disease.
The European Society of Cardiology and European Association for Cardio-Thoracic Surgery have released a focused update on dual antiplatelet therapy use in coronary heart disease.
Furosemide-induced acute pancreatitis can occur several hours to up to 7 weeks after starting treatment.
Smoking, duration of diabetes, and male sex were among several independent predictors of silent coronary artery disease in patients with asymptomatic diabetes.
Platelet aggregation levels did not predict cardiovascular events in patients with stable coronary artery disease.
Individuals with psoriasis have a greater risk for noncalcified coronary plaque burden compared with healthy individuals and patients with hyperlipidemia.
A genetic predisposition to elevated serum calcium levels may increase the risk for coronary artery disease and myocardial infarction.
Two-hour postload glucose (2h-PG) may be a better predictor of cardiovascular events in patients with coronary artery disease.
No differences were observed between pravastatin and usual care for CHD events, cause-specific deaths, stroke, cancer, and combination fatal CHD or nonfatal MI.
Individuals with adverse childhood experience may be at greater risk for major adverse cardiovascular events.
A gluten-free diet is not recommended for individuals without celiac disease to prevent coronary heart disease.
Fourteen percent of study participants experienced incident athersclerotic cardiovascular disease events.
Hair whitening score, hypertension, and dyslipidemia were all independent predictors of atherosclerotic coronary artery disease.
Fasting pancreatic polypeptide may be a marker for macrovascular disease.
Patients with statin intolerance had a 36% higher rate of recurrent myocardial infarction compared with patients with high statin adherence.
Revised coronary revascularization criteria rated whether coronary interventions are appropriate in tables organized according to practice patterns.
Risk of cardiovascular disease gradually increased in patients undergoing darunavir therapy.
The HART test has been found to be more accurate than standard diagnostic methods in identifying coronary artery disease.
Rivaroxaban met its primary end point well ahead of the scheduled March 2018 trial conclusion.
Low hemoglobin levels independently predicted all-cause, cardiovascular, and noncardiovascular mortality in patients with coronary artery disease.
Renin-angiotensin system inhibitors reduced cardiovascular events in patients with coronary artery disease when compared with placebo but not active controls.
Three revascularization techniques were compared in patients with concomitant carotid and coronary artery disease undergoing CABG.
Higher SYNTAX scores may predict major cardiovascular events in patients with coronary artery disease and diabetes.
A prospective cohort study in 66 patients with end-stage renal disease was conducted to determine the link between renal and coronary heart diseases.
Patients with systemic lupus erythematosus had a net progression of mean carotid intima-media thickness, with or without depression.
A large number of patients with psoriatic arthritis may have silent coronary artery disease.
The influenza vaccine has demonstrated protective effectiveness against acute MI between 19% and 45%.
Patients undergoing left main PCI treated by high-volume operators had a significantly lower risk for short- and long-term cardiac death compared with those treated by less experienced operators.
Patients who underwent intravascular ultrasound guided drug-eluting stent implantation vs angiography-guided implantation had reductions in MACE.
The European League Against Rheumatism (EULAR) has released updated guidelines for cardiovascular disease risk assessment in patients with rheumatoid arthritis.
The strongest predictor of depression in patients with chronic stable angina was an episode of depression within the past 10 years.
Women with moderate or severe coronary artery calcification had higher risks of death, MI, or target revascularization, despite new-generation drug-eluting stents.
Cumulative cigarette exposure correlated with increased measures of left ventricular mass and worse diastolic function.
Specificity, or less overtreatment, increased from 15% to 25% for both coronary heart disease and cardiovascular disease
Patients with heart failure or less-frequent angina were most likely to have their condition under-recognized.
Invasive coronary physiological evaluation is safe during exercise in patients with severe aortic stenosis.
MACE rate was 6.8% at 18 months, and the rates of cardiac mortality, MI, and target lesion revascularization were 1.8%, 5.2%, and 4.0%, respectively.
Physical activity, even of moderate intensity, had a significant impact on young women's risk of developing coronary heart disease.
Clinical outcomes, medical costs, and quality of life were similar between CTA and selective fractional flow reserve with CTA in patients with stable chest pain.
Assessments of left atrial axial area index, epicardial fat volume, and thoracic aortic calcification improve prediction of cardiovascular events.
Fractional myocardial mass per minimal luminal diameter demonstrated a good correlation with fractional flow reserve in a per-vessel analysis.
Statins were associated with a 44% risk reduction for coronary artery disease in patients with familial hypercholesterolemia.
Researchers sought to determine the contributions of baseline coronary artery calcification scanning, follow-up CAC, and CAC progression on incident cardiovascular disease.
An up to 5-fold increased risk of coronary heart disease hazards was observed in the familial hypercholesterolemia phenotype group for ages 20 to 29.
Radial access was associated with a 29% relative risk reduction in all-cause mortality and a 16% relative risk reduction in major adverse cardiovascular end points compared with femoral access.
The imaging system detected coronary stenoses with excellent sensitivity and negative likelihood ratio in patients undergoing cardiac valve surgery.
A meta-analysis compared methods of percutaneous coronary intervention for the treatment of stenosis in small coronary arteries.
Bioresorbable vascular scaffolds were associated with more post-procedural asymmetric and eccentric morphology compared to metallic everolimus-eluting stents.
Subclinical Atherosclerosis Not Predicted by Average Leucocyte Telomere Length or Short Telomere Load
Researchers studied associations between telomeres and atherosclerosis burden in femoral and carotid arteries in 3 regression models.
Cholesterol efflux capacity remained inversely associated with incident atherosclerotic cardiovascular disease without attenuation in an adjusted model.
Percutaneous coronary intervention use has increased among patients with diabetes and multivessel coronary artery disease who present with non-ST-segment elevation myocardial infarction.
ACC/AHA Equation Overestimates Atherosclerotic Cardiovascular Disease Risk in Large Multiethnic Cohort
The ACC/AHA pooled cohort risk equation significantly overestimated 5-year predicted risk of atherosclerotic cardiovascular disease events across sociodemographic groups.
Treatment with drug-coated balloon in infrapopliteal arteries was associated with favorable angiographic efficacy after 1 year.
Adjusted hazard ratios for mortality suggested similar outcomes in carotid artery stenting and carotid endarterectomy.
Adding the number of vessels with coronary artery calcium helped better predict the number of coronary heart disease and cardiovascular disease events in survival analysis.
The observed risk of abdominal aortic aneurysms increased with severity of psoriasis.
ACC/AHA Release Dual Antiplatelet Therapy Guideline-Focused Update for Patients With Coronary Artery Disease
American College of Cardiology and American Heart Association released a guideline focused update on dual antiplatelet therapy in patients with coronary artery disease.
Researchers used data from the COGENT trial to test proton-pump inhibitor therapy in patients taking low- and high-dose aspirin.
Patients with severe aortic stenosis without coronary artery disease demonstrated reduced myocardial perfusion reserve.
Femoral atherosclerosis had a stronger association with cardiovascular risk factors and coronary calcium than carotid atherosclerosis.
First occurrence of non-cardiovascular disease diagnosis in participants with coronary artery calcium score of 0 was 11.0, 22.5% for a CAC score of 1-400, and 36.9% for CAC >400.
The first in-human clinical imaging of coronary arteries in vivo using dual modality optical coherence tomography and near-infrared autoflurorescence may provide more detailed information than structural imaging alone.
Coronary heart disease patients with high triglyceride levels have an increased 22-year mortality risk, independent of high-density lipoprotein cholesterol levels.
According to a PEGASUS-TIMI 54 substudy, ticagrelor 60 mg twice a day achieved similar target levels of platelet inhibition as ticagrelor 90 mg.
Previous coronary stent implantation may serve as an independent risk factor for major adverse cardiac and cerebrovascular events in noncardiac surgery.
The Cardiology Advisor Articles
- Cardiac Troponin Elevation Predicts Major Adverse Events Even Without Specific Diagnosis
- How Has the Medicaid Expansion Affected Patients Hospitalized With Acute MI?
- Macitentan Not Superior to Placebo for Improving Exercise Capacity in Eisenmenger Syndrome
- Association Between Statins and Depression Likely Mediated by Confounding
- Occupational Metal, Pesticide Exposure May Be Associated With Increased CVD Risk
- ASH Develops Practice Guidelines for Venous Thromboembolism
- Tetralogy of Fallot: Long-Term Outcomes After Surgical Repair
- Cardiac Troponin Elevation Predicts Major Adverse Events Even Without Specific Diagnosis
- Catheter Ablation Superior to Drug Therapy for Atrial Fibrillation in Heart Failure
- Trends in Endocarditis Incidence After Implementation of 2007 AHA Recommendations
- Researchers Identify Golden Ratio Between Pulmonary Pressure Components in PAH
- FDA: Potential Increased Mortality With Paclitaxel-Coated Balloons, Stents for PAD
- Inhaled Dry Powder Formulation of Treprostinil Well Tolerated in PAH
- Elevated Myocardial T1 Associated With Increased Septal Angle in PAH
- Pulmonary Hypertension Intensive Care Options Depend on Treatment Goals