Virginia A. Schad, PharmD, RPh

How do substance abuse and depression affect the risk for premature mortality in patients with common chronic respiratory and other conditions?

A recent Chinese study sought to identify clinical predictors of pulmonary hypertension combined with obstructive sleep apnea.

Researchers examining COVID-19 data from a 13-month period found variations in US usage of dexamethasone, remdesivir, and hydroxychloroquine.

Researchers sought to delineate the role of cystic fibrosis transmembrane conductance regulator (CFTR) in pulmonary arterial hypertension pathogenesis through observational and interventional experiments in human tissues and animal models.

Further metabolite-based analysis may help identify the mechanisms underlying pulmonary dysfunction in COVID-19 survivors and provide potential therapeutic targets in the future.

Chronic obstructive pulmonary disease (COPD) is associated with lower use of beta-blockers and worse health status and is an independent predictor of cardiovascular and noncardiovascular hospitalizations.

In patients with COPD, subclinical left ventricular systolic dysfunction is likely to be detected when measured by tissue Doppler imaging, even in patients without pulmonary hypertension.

Thoracic organ transplantation remains a viable treatment option in patients with Eisenmenger Syndrome, although these patients are considered higher risk than other potential transplant recipients.

Bayesian machine learning algorithms can improve discrimination of risk stratification in pulmonary arterial hypertension.

In patients with pulmonary arterial hypertension, renal function is important for determining mortality risk and improves stratification of risk.