BET Inhibitor Reverses Vascular Remodeling in Pulmonary Arterial Hypertension
At a clinically relevant dose, RVX208 improved hemodynamics and reversed pulmonary vascular remodeling in certain pulmonary arterial hypertension models in rats.
All articles by Sheila Jacobs
Dry Powder Formulation of Treprostinil Appears Safe, Tolerable in PAH
Use of the dry powder formulation of treprostinil, known as LIQ861, has demonstrated safety and tolerability in patients with pulmonary arterial hypertension beyond 2 weeks.
Could Spectral Detector CT Offer Accurate Diagnosis of CTEPH?
The use of spectral-detector computed tomography offers a highly accurate method to diagnose chronic thromboembolic pulmonary hypertension.
Balloon Pulmonary Angioplasty Improves Hemodynamics in Inoperable CTEPH
Following the use of balloon pulmonary angioplasty, patients with inoperable chronic thromboembolic pulmonary hypertension had decreased mean pulmonary artery pressure, pulmonary vascular resistance, and mean right arterial pressure.
CAD Risk Reduced With Statin Use in Asthma-COPD Overlap Syndrome
The risk for coronary artery disease in patients with asthma-COPD overlap syndrome who used statins was lower regardless of the duration of treatment.
PAH Mortality Predicted by Exercise Capacity and QoL Assessments
Comprehensive assessments of exercise capacity and quality of life can be used to predict 2-year mortality in patients with pulmonary arterial hypertension.
Primary Hypertension May Not Affect Prognosis of Postmenopausal Osteoporosis
The presence of primary hypertension does not appear to have an effect on the prognosis of postmenopausal osteoporosis.
Active CVD Screening Should Be Conducted in Comorbid COPD, Obesity
Hypertension and diabetes are especially prevalent comorbidities in obese patients with chronic obstructive pulmonary disease.
Increased Stroke Risk Following Surgical vs Transfemoral Aortic Valve Replacement
Researchers evaluated stroke risk and its effect on quality of life after surgical aortic valve replacement vs transfemoral transcatheter aortic valve.
Treprostinil May Have Antithrombotic Effect in Pediatric Pulmonary Hypertension
Treatment with treprostinil has demonstrated potential antithrombotic mechanisms of action in pediatric patients with pulmonary arterial hypertension.
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