Scott Charles Howard

All articles by Scott Charles Howard


OVERVIEW: What every practitioner needs to know Thrombosis is a common problem among adults, and management of many of the diverse clinical presentations has been subjected to randomized clinical trials. In pediatrics, most treatment is based on that used in adults (with adjustment of drug doses, of course). However, there is universal agreement about the…

Tumor lysis syndrome

OVERVIEW: What every practitioner needs to know Tumor lysis syndrome (TLS) is defined as the combination of hyperuricemia, hyperphosphatemia, hyperkalemia, and acute kidney injury that results from lysis of cancer cells when treatment is initiated. The syndrome can lead to fatal cardiac dysrhythmias and acute kidney injury, so all patients potentially at risk for TLS…

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