Gary Rothbard, MD, MS

A greater quantity of oral nitrate-reducing bacteria was found to be associated with reduced plasma glucose and insulin resistance in young to middle-aged adults.

Women were found to be at a lower risk for major adverse cardiovascular events after non-ST-segment elevation acute coronary syndromes compared with men.

No causal association between elevated red cell distribution width and pulmonary arterial hypertension was established.

Associations were established between recovery from and development of metabolic syndrome and reduced and elevated risk for major adverse cardiovascular events, respectively.

In patients with abnormal vital signs presenting to the emergency department who are suspected of having a pulmonary embolism, a negative focused cardiac ultrasound examination may be associated with reduced odds of a pulmonary embolism diagnosis.

In patients with acute coronary syndrome, the early in-hospital addition of evolocumab to high-dose statin therapy was found to be safe, well tolerated, and efficacious in reducing low-density lipoprotein cholesterol levels.

Clinicians should be aware of the pitfalls of noninferiority trials in cardiology, and not accept noninferiority on face value.

Implantation of the self-expanding Biovalve transcatheter heart valve for the treatment of severe aortic stenosis was deemed to be safe, with clinical outcomes similar to those of other first-generation devices designed for the same indication.

Patients with new-onset vs patients without or with preexisting atrial fibrillation who underwent transcatheter aortic valve replacement were found to have a higher risk for all-cause mortality.