Guidance is provided for cardiovascular specialists for the initiation and management of glucose-lowering therapies in patients with type 2 diabetes.
![The most frequent cardiovascular manifestations of AS are aortic insufficiency and conduction disorders.[2] Up to 20% of patients with AS have conduction disorders, of which atrioventricular block is the most common.[5,6] Compared with the general population, patients with AS have a 30% to 50% increase in the risk of acute coronary syndromes, deep venous thromboembolism, pulmonary embolism, or stroke.[8] They also have a 25% to 60% greater risk of ischemic heart disease, congestive heart failure, and valvular heart disease.[9] Heart failure may occur secondary to mitral insufficiency.[2] Aortic dissection, which is a rare but frequently fatal complication of aortic insufficiency, has also been observed in patients with AS.[2] Other potential cardiovascular complications include left ventricular diastolic dysfunction, pericarditis, myocardial disease, peripheral vascular disease, and hypertension.[2,3,5]](https://3fvcugvijkt9bj7w3wf2t712-wpengine.netdna-ssl.com/wp-content/uploads/sites/17/2019/01/thinkstockphotos474641458101_1032729-544x306.jpg)
A reduced dose of prasugrel compared with the standard dose of ticagrelor was associated with maintained anti-ischemic efficacy and safety in elderly or low-weight patients with acute coronary syndrome.
Elevated triglyceride levels were found to be independently associated with adverse cardiovascular outcomes in patients with type 2 diabetes and coronary artery disease.
Use of radial artery vs saphenous vein for coronary artery bypass grafting was found to be associated with a reduced long-term risk for a composite of cardiovascular outcomes.
The 6-minute walk test was found to have limited value for the identification of response to cardiac resynchronization therapy in patients with mild heart failure and left bundle branch block.
In patients with COVID-19–related ARDS, increased troponin T levels were found to be common and may be linked to disease severity.
Cardiac troponin may aid clinicians in determining stage classification and stratifying risk for myocardial injury among patients with COVID-19.
Women who had previously taken β-blockers for hypertension were found to be at increased risk for heart failure in new-onset coronary heart disease.
Continuous positive airway pressure was effective for preventing cardiovascular disease in patients with severe obstructive sleep apnea.
Insufficient calorie intake was found to be independently associated with a poorer quality of life and greater burden of hospital readmission among older patients hospitalized for heart failure.
