Atrial Fibrillation

Vasopressin plus catecholamines lowers risk of atrial fibrillation in distributive shock

In this meta-analysis, addition of vasopressin to catecholamine vasopressors was associated with a lower risk for atrial fibrillation compared with catecholamine monotherapy. However, while there was decreased mortality with vasopressin plus catecholamines, this difference was not seen when restricting analysis to studies with a low risk for bias.

Long-Term Cardiovascular Risk for Endometrial Cancer Survivors

Long-Term Cardiovascular Risk for Endometrial Cancer Survivors

Endometrial cancer survivors have an elevated risk of various adverse long-term cardiovascular outcomes.

Andexxa Approved for Reversing Anticoagulant Activity of Rivaroxaban, Apixaban

Andexxa Approved for Reversing Anticoagulant Activity of Rivaroxaban, Apixaban

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Andexxa, a recombinant modified human Factor Xa (FXa) protein, was approved under the FDA's Accelerated Approval pathway.

Afib Risk Not Affected by Borderline ABI in Peripheral Artery Disease

Afib Risk Not Affected by Borderline ABI in Peripheral Artery Disease

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Peripheral artery disease with a borderline ankle-branchial index appears not to increase the risk for atrial fibrillation.

Anxiety May Increase Stroke, Intracranial Hemorrhage in Atrial Fibrillation

Anxiety May Increase Stroke, Intracranial Hemorrhage in Atrial Fibrillation

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Anxiety may increase the risk for ischemic stroke and intracranial hemorrhage in patients with atrial fibrillation.

Caffeine Does Not Appear to Be Linked to Risk for Arrhythmia

Caffeine Does Not Appear to Be Linked to Risk for Arrhythmia

Regular intake of coffee and tea seems safe and may be beneficial, although energy drinks may increase risk for arrhythmia.

Nut Consumption Associated With Reduced Risk for Atrial Fibrillation

Nut Consumption Associated With Reduced Risk for Atrial Fibrillation

Possible correlation also seen for nut consumption with reduced risk for heart failure, myocardial infarction, and abdominal aortic aneurysm.

Praxbind Gains Full FDA Approval as Pradaxa Reversal Agent

Praxbind Gains Full FDA Approval as Pradaxa Reversal Agent

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Complete reversal was seen within 4 hours in the majority of patients, as measured by ecarin clotting time (ECT 82%) or diluted thrombin time (dTT 99%). In addition, there was a low late of thrombotic events and no new safety events were reported.

Pulmonary Arterial Hypertension Outcomes With Atrial Arrhythmia

Pulmonary Arterial Hypertension Outcomes With Atrial Arrhythmia

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Increased right atrial and pulmonary wedge pressures and increased thyroid disease prevalence were associated with atrial arrhythmia development in idiopathic or systemic sclerosis-related pulmonary arterial hypertension.

Lower Thromboembolic Risk With New Afib After CABG vs NVAF

Lower Thromboembolic Risk With New Afib After CABG vs NVAF

For patients post coronary artery bypass graft surgery, new-onset postoperative atrial fibrillation is associated with lower long-term thromboembolic risk than that seen among patients with nonvalvular atrial fibrillation.

NSAID Use Linked to Afib Risk in Middle-Aged Asian Population

NSAID Use Linked to Afib Risk in Middle-Aged Asian Population

Risk up with use of non-selective NSAIDs and combined use of selective, non-selective NSAIDs.

Depression, Antidepressant Use May Up Risk of Atrial Fibrillation

Depression, Antidepressant Use May Up Risk of Atrial Fibrillation

Depression and use of an antidepressant are associated with atrial fibrillation.

Atrial Fibrillation Mortality May Increase With Digoxin

Atrial Fibrillation Mortality May Increase With Digoxin

Compared with patients not taking digoxin, patients with a serum digoxin concentration of ≥1.2 ng/mL had a 56% increased hazard of mortality.

Influenza Vaccination May Reduce Mortality Risk in Heart Failure

Influenza Vaccination May Reduce Mortality Risk in Heart Failure

A meta-analysis sought to determine the effect of influenza vaccination on cardiac-related mortality in patients with heart failure.

Ischemic Stroke Risk in Atrial Fibrillation Varies by Race

Ischemic Stroke Risk in Atrial Fibrillation Varies by Race

African-Americans are at an increased risk of developing an ischemic stroke before or after atrial fibrillation diagnosis compared with whites.

Digital Adherence Devices: Preventing Strokes in Afib One Reminder at a Time

Digital Adherence Devices: Preventing Strokes in Afib One Reminder at a Time

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Using digital adherence devices to improve medication adherence in patients with atrial fibrillation may reduce the rate of ischemic strokes.

Anticoagulants in Elderly With Afib, CKD May Increase Stroke Risk

Anticoagulants in Elderly With Afib, CKD May Increase Stroke Risk

Anticoagulants are associated with increased risk for ischemic stroke and hemorrhage in older patients with chronic kidney disease and a new diagnosis of atrial fibrillation.

Catheter ablation of atrial fibrillation in heart failure reduces mortality and hospitalization: The CASTLE-AF trial

Compared with medical therapy alone, catheter ablation of atrial fibrillation in patients with heart failure reduced the risk for all-cause mortality and hospitalization.

Targeting Underlying Conditions May Improve Sinus Rhythm in Atrial Fibrillation

Targeting Underlying Conditions May Improve Sinus Rhythm in Atrial Fibrillation

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Patients with persistent atrial fibrillation who received targeted therapy saw improvements in sinus rhythm as well as reductions in blood pressure, cholesterol, and weight.

A 45-Year-Old Man Presents to the ED With Shortness of Breath, Confusion

A 45-Year-Old Man Presents to the ED With Shortness of Breath, Confusion

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A 45-year-old man presents to the emergency department with some mental confusion and near syncope.

Atrial Fibrillation Treated With LAA Occlusion Reduces Thromboembolism Risk

Atrial Fibrillation Treated With LAA Occlusion Reduces Thromboembolism Risk

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Surgical left atrial appendage occlusion is associated with a lower risk for thromboembolism-related hospital readmission in older patients with atrial fibrillation who undergo cardiac surgery.

A 35-Year-Old Pregnant Woman Presents With Progressive Dyspnea and Palpitations

A 35-Year-Old Pregnant Woman Presents With Progressive Dyspnea and Palpitations

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A 35-year-old pregnant woman presents to the emergency department with progressive dyspnea and palpitations that have worsened during the last 3 weeks.

Stroke, Other CV Risks, Increased With Migraine

Stroke, Other CV Risks, Increased With Migraine

Migraine was associated with elevated risks of myocardial infarction, stroke (ischemic and hemorrhagic), venous thromboembolism, and atrial fibrillation or flutter.

Atrial Fibrillation With Heart Failure: Better Outcomes With Ablation

Atrial Fibrillation With Heart Failure: Better Outcomes With Ablation

Catheter ablation was associated with a significant reduction in a composite end point of death from any cause or hospitalization for worsening heart failure in patients with atrial fibrillation.

Clinical Case: Appropriate Cardiovascular Workup After Acute Hemiparesis

Clinical Case: Appropriate Cardiovascular Workup After Acute Hemiparesis

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The next best diagnostic step in the workup of acute ischemic stroke in context of updated 2018 guidelines is discussed.

Ischemic Stroke Risk in Atrial Flutter vs Fibrillation

Ischemic Stroke Risk in Atrial Flutter vs Fibrillation

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Patients with atrial fibrillation have a higher risk for ischemic stroke compared with patients with atrial flutter.

Bleeding, Thromboembolic Events With Apixaban Interruption During Afib Ablation

Bleeding, Thromboembolic Events With Apixaban Interruption During Afib Ablation

Uninterrupted and minimally interrupted apixaban are associated with low rates of thromboembolic events in patients undergoing catheter ablation for nonvalvular afib.

Electrocardiogram Use for Afib, CVD Prevention Reviewed by USPSTF

Electrocardiogram Use for Afib, CVD Prevention Reviewed by USPSTF

Current evidence is inadequate to assess benefits and harms of ECG screening for atrial fibrillation.

Measuring Cost-Effectiveness of DOACs, Warfarin for Stroke Prevention

Measuring Cost-Effectiveness of DOACs, Warfarin for Stroke Prevention

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Cost-effective DOACs like apixaban prevent strokes better than warfarin in patients with atrial fibrillation.

Bleeding Risk, Stroke Outcomes With Edoxaban vs Enoxaparin-Warfarin for Cardioversion of Atrial Fibrillation

Bleeding Risk, Stroke Outcomes With Edoxaban vs Enoxaparin-Warfarin for Cardioversion of Atrial Fibrillation

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In patients with atrial fibrillation at high risk for stroke, edoxaban is associated with lower rates of cardiovascular death events.

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