Comparative Recurrence Risk of Isolated SVT, Proximal DVT Post-AC Discontinuation

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Incidence risk is lower with first superficial vein thrombosis after stopping anticoagulant therapy compared to those with proximal deep vein thrombosis.
Incidence risk is lower with first superficial vein thrombosis after stopping anticoagulant therapy compared to those with proximal deep vein thrombosis.

HealthDay News — Patients with isolated superficial vein thrombosis (iSVT) have a similar overall risk of recurrence as those with proximal deep vein thrombosis (DVT), according to a study published online in the Journal of Thrombosis and Haemostasis.

Jean-Philippe Galanaud, MD, PhD, from Montpellier University in France, and colleagues used data from a prospective, multicenter study to examine the risk and type of venous thromboembolic (VTE) recurrence at 3 years and after anticoagulants were stopped. Recurrence was assessed for 285 patients with a first objectively confirmed iSVT without cancer and 262 patients with a first proximal DVT without cancer.

The researchers found that iSVT patients had a similar overall incidence of VTE recurrence compared with proximal DVT patients (5.4% vs 6.5% per patient-year; adjusted hazard ratio [aHR]: 0.9; 95% CI, 0.5-1.6), but they had increased risk of iSVT recurrence (2.7% vs 0.6%; aHR: 5.9; 95% CI, 1.3-27.1) and reduced risk of deep-VTE events (2.5% vs 5.9%; aHR: 0.4; 95% CI, 0.2-0.9).

"In patients with a first iSVT without cancer, after stopping anticoagulants, the incidence of deep-VTE recurrence is twice lower than that of proximal DVT patients but overall risk of recurrence is similar," the authors write.

Reference

Galanaud J-P, Sevestre M-A, Pernod G, et al. Long-term risk of venous thromboembolism recurrence after isolated superficial vein thrombosis [published online March 20, 2017]. J Thromb Haemost. doi: 10.1111/jth.13679

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