Diseases of Pulmonary Vasculature

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Worsening Shortness of Breath in Patient With Hypertension, Afib

Worsening Shortness of Breath in Patient With Hypertension, Afib

A 72-year-old man with hypertension and paroxysmal atrial fibrillation presents to the emergency department because he has been experiencing worsening shortness of breath.

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Improving Risk Stratification, Diagnostic Accuracy in PAH With Cardiopulmonary Exercise Testing

Improving Risk Stratification, Diagnostic Accuracy in PAH With Cardiopulmonary Exercise Testing

Cardiopulmonary exercise testing can be an important diagnostic and prognostic tool in pulmonary arterial hypertension.

Connective Tissue Diseases in Comorbid PAH: A Case for Separating SSc, SLE

Connective Tissue Diseases in Comorbid PAH: A Case for Separating SSc, SLE

Recent evidence suggests that systemic sclerosis and systemic lupus erythematosus comorbid with pulmonary arterial hypertension should be considered separate diseases.

Improved Pulmonary Arterial Hypertension Risk Prediction Tools Needed

Improved Pulmonary Arterial Hypertension Risk Prediction Tools Needed

The use of a risk calculator aimed at achieving a low-risk profile in PAH trials is discussed.

Lung Transplantation in Pulmonary Arterial Hypertension: An Overview

Lung Transplantation in Pulmonary Arterial Hypertension: An Overview

Evaluating diagnosis and treatment options for pulmonary arterial hypertension.

Worsening Shortness of Breath in a 40-Year-Old Woman: A Case Study

Worsening Shortness of Breath in a 40-Year-Old Woman: A Case Study

A 40-year-old woman presents with worsening shortness of breath after being treated with long-acting nifedipine for 2 years.

Pulmonary Arterial Hypertension: Mechanisms of Exercise Intolerance

Pulmonary Arterial Hypertension: Mechanisms of Exercise Intolerance

Exercise intolerance is a hallmark symptom of pulmonary arterial hypertension.

Diagnostic Value of Bronchoalveolar Lavage in Idiopathic Pulmonary Fibrosis

Diagnostic Value of Bronchoalveolar Lavage in Idiopathic Pulmonary Fibrosis

The diagnostic value of bronchoalveolar lavage in idiopathic pulmonary fibrosis is evaluated.

Chronic Thromboembolic PH Diagnosis and Management Update: Expert Q&A

Chronic Thromboembolic PH Diagnosis and Management Update: Expert Q&A

Development of CTEPH is associated with traditional thrombotic risk factors, including thrombophilias and inflammatory processes.

Pulmonary Arterial Hypertension: Treatment Tailored by Race and Ethnicity

Pulmonary Arterial Hypertension: Treatment Tailored by Race and Ethnicity

Future clinical trials on pulmonary arterial hypertension should include patients from diverse racial and ethnic backgrounds.

Bronchopulmonary Dysplasia and Pulmonary Hypertension in Preterm Neonates

Bronchopulmonary Dysplasia and Pulmonary Hypertension in Preterm Neonates

The most common chronic respiratory morbidity affecting preterm neonates is bronchopulmonary dysplasia.

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Pulmonary Arterial Stiffness Related to mPAP and Heart Rate in Idiopathic PAH

Pulmonary Arterial Stiffness Related to mPAP and Heart Rate in Idiopathic PAH

Pulmonary arterial stiffness was related to mean pulmonary arterial pressure and heart rate in patients with untreated idiopathic pulmonary arterial hypertension.

Prognostic Model for Mortality in Pediatric Pulmonary Hypertension

Prognostic Model for Mortality in Pediatric Pulmonary Hypertension

The Pediatric Index Pulmonary Hypertension Intensive Care Mortality model was compared with the Pediatric Risk of Mortality 2 and 3 models to determine the best model for predicting mortality.

RV Trabecular Complexity Fractal Analysis: Measuring Remodeling in PH

RV Trabecular Complexity Fractal Analysis: Measuring Remodeling in PH

The fractal dimension of right ventricular trabecular complexity was a good reproducible marker of remodeling in pulmonary hypertension.

RV Base/Apex Ratio May Help Diagnose Pulmonary Arterial Hypertension in Children

RV Base/Apex Ratio May Help Diagnose Pulmonary Arterial Hypertension in Children

Right ventricular base/apex ratio reference values may help clinicians diagnose children with pulmonary arterial hypertension.

Improved Counseling Needed in Pregnant Patients With Pulmonary Arterial Hypertension

Improved Counseling Needed in Pregnant Patients With Pulmonary Arterial Hypertension

Many healthcare providers reported that they often do not have the time to counsel their patients with pulmonary arterial hypertension on pregnancy risks.

PAH in Congenital Heart Disease: Expert Q&A on Challenges and Advances

PAH in Congenital Heart Disease: Expert Q&A on Challenges and Advances

Management strategies were discussed for subtypes of PAH-congenital heart disease including Eisenmenger syndrome, PAH with persistent systemic to pulmonary shunts, and PAH with small or coincidental defect or PAH after defect closure.

Cyanosis From PH or Congenital Heart Disease Responds Well to IV Ferrous Carboxymaltose

Cyanosis From PH or Congenital Heart Disease Responds Well to IV Ferrous Carboxymaltose

After iron supplementation, patients with cyanosis experienced significant improvements in hemoglobin concentration, hematocrit, mean corpuscular volume, ferritin, and transferrin saturation

Sildenafil, Bosentan Combination vs Sildenafil Monotherapy in SSc-Associated PAH

Sildenafil, Bosentan Combination vs Sildenafil Monotherapy in SSc-Associated PAH

There was no significant difference in efficacy between sildenafil and bosentan initial combination therapy and sildenafil monotherapy in patients with systemic sclerosis-related pulmonary arterial hypertension.

CTEPH Increases Risk for Sleep Disordered Breathing

CTEPH Increases Risk for Sleep Disordered Breathing

Precapillary pulmonary hypertension and obstructive sleep apnea may be causative factors for central sleep apnea and pulmonary hypertension, respectively.

Arrhythmia Associated With Higher Mortality in Congenital Heart Disease-Related PAH

Arrhythmia Associated With Higher Mortality in Congenital Heart Disease-Related PAH

Arrhythmia was a significant predictor of mortality in adult patients with congenital heart disease and pulmonary arterial hypertension.

Composite Echo Score Predicts PH in Interstitial Lung Disease

Composite Echo Score Predicts PH in Interstitial Lung Disease

The variables for the stepwise echocardiographic score included right ventricular systolic pressure, early pulmonary regurgitation gradient, right atrial area size, tricuspid regurgitation velocity, left ventricle eccentricity index, and right ventricle fractional area change.

Brain Natriuretic Peptide Shows Promise as Biomarker in Group 1 PAH

Brain Natriuretic Peptide Shows Promise as Biomarker in Group 1 PAH

There was a significant relationship between brain natriuretic peptide levels and mortality in patients with group 1 pulmonary arterial hypertension.

Pulmonary Hypertension Has Adverse Effect on Post-Lung Transplant Survival

Pulmonary Hypertension Has Adverse Effect on Post-Lung Transplant Survival

The 1-year survival rate after lung transplantation in patients with a mean pulmonary arterial pressure ≥25 mm Hg was lower than the survival rate of those with a mean pulmonary arterial pressure <25 mm Hg.

Single-Beat Approach Estimates Preload Recruitable Stroke Work Relationship in PAH

Single-Beat Approach Estimates Preload Recruitable Stroke Work Relationship in PAH

A single-beat estimation of preload recruitable stroke work and its coupling with pulmonary arterial load in pulmonary arterial hypertension provided high accuracy for evaluating right ventricular contractility.

PAH Risk, Mortality Increased by Disturbances in Male Sex Hormones

PAH Risk, Mortality Increased by Disturbances in Male Sex Hormones

Men with higher estradiol and estradiol/testosterone levels had an increased risk for pulmonary arterial hypertension.

Serum Chloride Linked With Survival in Pulmonary Arterial Hypertension

Serum Chloride Linked With Survival in Pulmonary Arterial Hypertension

Serum chloride was a strong and independent predictor of mortality at 6 months after a pulmonary arterial hypertension diagnosis.

Egg-and-Banana Sign Has High Specificity for Pulmonary Hypertension Diagnosis

Egg-and-Banana Sign Has High Specificity for Pulmonary Hypertension Diagnosis

The "egg-and-banana" sign is a valid computed tomography marker of pulmonary hypertension.

Oral Anticoagulant Effective in Recurrent VTE Prevention in Cancer Patients

Oral Anticoagulant Effective in Recurrent VTE Prevention in Cancer Patients

At the end of 6 months, the rate of VTE recurrence was 4% among rivaroxaban patients vs 11% in the dalteparin arm (hazard ratio [HR] 0.43, 95% CI: 0.19 to 0.99).

Veno-Arterial Extracorporeal Membrane Oxygenation Improves Survival in Pulmonary Embolism

Veno-Arterial Extracorporeal Membrane Oxygenation Improves Survival in Pulmonary Embolism

A protocolized study including initiation of VA-ECMO may reduce mortality in patients with massive PE.

Predictive Value of Idiopathic PAH Risk Assessment Using Comorbidities, Age

Predictive Value of Idiopathic PAH Risk Assessment Using Comorbidities, Age

Ischemic heart disease and kidney dysfunction were identified as 2 comorbidities that may affect outcomes in idiopathic pulmonary arterial hypertension.

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