Pulmonary Arterial Hypertension

PAH: eGFR Changes May Predict Survival, Hospitalizations

PAH: eGFR Changes May Predict Survival, Hospitalizations

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A decrease in baseline estimated glomerular filtration rate in PAH may be a predictor of hospitalization and mortality.

Oral Riociguat May Have Clinical Utility in Severe Pediatric Pulmonary Arterial Hypertension

Oral Riociguat May Have Clinical Utility in Severe Pediatric Pulmonary Arterial Hypertension

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Use of riociguat may be considered for severe pulmonary arterial hypertension in pediatric patients.

Lung Transplantation in Pulmonary Arterial Hypertension: An Overview

Lung Transplantation in Pulmonary Arterial Hypertension: An Overview

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Evaluating diagnosis and treatment options for pulmonary arterial hypertension.

Balloon Pulmonary Angioplasty Improves Hemodynamics in CTEPH

Balloon Pulmonary Angioplasty Improves Hemodynamics in CTEPH

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Balloon pulmonary angioplasty may improve hemodynamics in patients with CTEPH.

Worsening Shortness of Breath in a 40-Year-Old Woman: A Case Study

Worsening Shortness of Breath in a 40-Year-Old Woman: A Case Study

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A 40-year-old woman presents with worsening shortness of breath after being treated with long-acting nifedipine for 2 years.

Pulmonary Arterial Hypertension: Mechanisms of Exercise Intolerance

Pulmonary Arterial Hypertension: Mechanisms of Exercise Intolerance

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Exercise intolerance is a hallmark symptom of pulmonary arterial hypertension.

Impaired Cerebral Pressure-Flow Link in Pulmonary Arterial Hypertension

Impaired Cerebral Pressure-Flow Link in Pulmonary Arterial Hypertension

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Patients with pulmonary arterial hypertension may have an impaired cerebral pressure-flow relationship.

Improving Pulmonary Arterial Compliance in PAH: Riociguat vs PDE5 Inhibitors

Improving Pulmonary Arterial Compliance in PAH: Riociguat vs PDE5 Inhibitors

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Switching from a phosphodiesterase type 5 inhibitor to riociguat significantly improves pulmonary arterial compliance in patients with PAH.

Pulmonary Artery Compliance Predictive of Mortality in PAH With Adult CHD

Pulmonary Artery Compliance Predictive of Mortality in PAH With Adult CHD

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Pulmonary artery compliance may be an independent predictor of survival and prognosis in patients with pulmonary artery hypertension associated with congenital heart disease.

Methamphetamine-Associated PAH Worse Than Idiopathic PAH

Methamphetamine-Associated PAH Worse Than Idiopathic PAH

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Pulmonary arterial hypertension associated with the use of methamphetamine is a severe, progressive form of the disease.

Echocardiographic Evaluation Recommended for Hereditary Hemorrhagic Telangiectasia

Echocardiographic Evaluation Recommended for Hereditary Hemorrhagic Telangiectasia

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Patients with hereditary hemorrhagic telangiectasia may develop pulmonary hypertension.

Chronic Thromboembolic Pulmonary Hypertension, PAH Linked to Depression

Chronic Thromboembolic Pulmonary Hypertension, PAH Linked to Depression

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Patients with chronic thromboembolic pulmonary hypertension may have higher rates of depression compared to patients with PAH.

Prognostic Value of CT Signs of Pulmonary Veno-occlusive Disease

Prognostic Value of CT Signs of Pulmonary Veno-occlusive Disease

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Having at least 2 features of pulmonary veno-occlusive disease is linked to reduced survival rate in patients with SSc and PAH.

Borderline Pulmonary Hypertension Commonly Found During Right Heart Catheterization

Borderline Pulmonary Hypertension Commonly Found During Right Heart Catheterization

Borderline pulmonary hypertension is associated with increased risk of mortality in patients undergoing right heart catheterization.

Clinical Case: Man With COPD and Worsening Shortness of Breath

Clinical Case: Man With COPD and Worsening Shortness of Breath

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A case study is of worsening dyspnea in a patient with COPD is presented.

Chronic Thromboembolic PH Diagnosis and Management Update: Expert Q&A

Chronic Thromboembolic PH Diagnosis and Management Update: Expert Q&A

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Development of CTEPH is associated with traditional thrombotic risk factors, including thrombophilias and inflammatory processes.

Pulmonary Arterial Hypertension: Treatment Tailored by Race and Ethnicity

Pulmonary Arterial Hypertension: Treatment Tailored by Race and Ethnicity

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Future clinical trials on pulmonary arterial hypertension should include patients from diverse racial and ethnic backgrounds.

Bronchopulmonary Dysplasia and Pulmonary Hypertension in Preterm Neonates

Bronchopulmonary Dysplasia and Pulmonary Hypertension in Preterm Neonates

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The most common chronic respiratory morbidity affecting preterm neonates is bronchopulmonary dysplasia.

Right Ventricular Morphology Predicts Type of Pulmonary Hypertension

Right Ventricular Morphology Predicts Type of Pulmonary Hypertension

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Right ventricular base/apex ratio during systole can discriminate between types of pulmonary hypertension.

FDA Approves Bosentan for Pediatric Pulmonary Arterial Hypertension

FDA Approves Bosentan for Pediatric Pulmonary Arterial Hypertension

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Bosentan has been approved for use in pediatric pulmonary arterial hypertension in children aged 3 years or older.

Selexipag Associated With Reduced Morbidity, Mortality Risk in Connective Tissue Disease-Associated PAH

Selexipag Associated With Reduced Morbidity, Mortality Risk in Connective Tissue Disease-Associated PAH

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In patients with connective tissue disease-associated pulmonary arterial hypertension, selexipag may reduce risk for morbidity and mortality.

Survival in SLE-Related Pulmonary Arterial Hypertension Linked to Autoimmune Antibodies

Survival in SLE-Related Pulmonary Arterial Hypertension Linked to Autoimmune Antibodies

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Anti-U1 ribonucleoprotein antibodies may increase chances of survival in patients with pulmonary arterial hypertension as a complication of systemic lupus erythematosus.

Lower Extremity Edema in a Woman With Heart Failure: A Case Study

Lower Extremity Edema in a Woman With Heart Failure: A Case Study

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A middle-aged woman recently diagnosed with diastolic left heart failure now has increasing fatigue and worsening lower extremity edema.

Biomarkers Linking SLE-Associated Pulmonary Arterial Hypertension

Biomarkers Linking SLE-Associated Pulmonary Arterial Hypertension

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Mortality rates in SLE-associated pulmonary arterial hypertension are higher compared to the general SLE population even-though diagnostic and treatment strategy have improved in the last 50 years.

MRI Measures Can Predict Pulmonary Arterial HTN Outcome

MRI Measures Can Predict Pulmonary Arterial HTN Outcome

Researchers found that MRI had "moderate prognostic accuracy" when used to evaluate patients with pulmonary arterial hypertension (PAH).

Pulmonary Arterial Hypertension and Genetics: Interview With the Experts

Pulmonary Arterial Hypertension and Genetics: Interview With the Experts

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James E. Loyd, MD, and Wendy Chung, MD, PhD, offer insight into the role of genetics in pulmonary arterial hypertension.

Connective Tissue Disease-Associated Pulmonary Arterial Hypertension Treatments

Connective Tissue Disease-Associated Pulmonary Arterial Hypertension Treatments

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Initial combination therapy with ambrisentan and tadalafil reduced the risk for first clinical failure event in patients with connective tissue disease-associated pulmonary arterial hypertension.

New Metabolites Associated With Hemodynamic Indicators of Right Ventricular-Pulmonary Vascular Dysfunction Discovered

New Metabolites Associated With Hemodynamic Indicators of Right Ventricular-Pulmonary Vascular Dysfunction Discovered

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Researchers discovered 21 new metabolites associated with 2 or more hemodynamic indicators of right ventricular-pulmonary vascular function.

FDA Approved Selexipag for Pulmonary Arterial Hypertension

FDA Approved Selexipag for Pulmonary Arterial Hypertension

Selexipag, an oral IP prostacyclin receptor agonist, has been approved by the FDA to treat adults with pulmonary arterial hypertension.

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