Prevention

Genetic Testing Recommended for Familial Hypercholesterolemia

Genetic Testing Recommended for Familial Hypercholesterolemia

Genetic testing should become the standard of care for patients with definite or probable familial hypercholesterolemia.

Is There a Benefit to Extended Thromboprophylaxis With Rivaroxaban After Discharge?

Is There a Benefit to Extended Thromboprophylaxis With Rivaroxaban After Discharge?

Rivaroxaban does not lower risk of symptomatic venous thromboembolism and related death in medical patients after hospital discharge, compared to placebo.

FDA Publishes Final Guidance on Heparin-Containing Devices

FDA Publishes Final Guidance on Heparin-Containing Devices

By

The intent of the document is to help reduce heparin product overdose errors caused by misinterpretation of the drug strength displayed in the labeling.

Cardiac Changes Linked With Specific ARVs in Perinatally Acquired HIV

Cardiac Changes Linked With Specific ARVs in Perinatally Acquired HIV

By

Individual antiretroviral medications have been linked with changes in cardiac structure in youths with perinatally acquired HIV.

ASPREE Trial: Aspirin Associated With Higher Mortality, Hemorrhage Risk in Older Adults

ASPREE Trial: Aspirin Associated With Higher Mortality, Hemorrhage Risk in Older Adults

By

The use of aspirin in healthy elderly patients as a preventative strategy was associated with no prolongation of long-term disability-free survival compared with placebo.

Algorithm Can Discriminate CVD Risk Across Range of Health Profiles

Algorithm Can Discriminate CVD Risk Across Range of Health Profiles

The Cardiovascular Disease Population Risk Tool algorithm, which includes 12 variables, can discriminate cardiovascular disease risk.

FDA to Review Praluent as Potential Treatment for MACE Risk Reduction

FDA to Review Praluent as Potential Treatment for MACE Risk Reduction

By

The sBLA is supported by data from the Phase 3 ODYSSEY OUTCOMES trial which included 18,924 patients who had experienced an acute coronary syndrome (ACS) in the previous 12 months.

FDA Grants Breakthrough Device Designation to Bloodless Hyperkalemia Test

FDA Grants Breakthrough Device Designation to Bloodless Hyperkalemia Test

The KardiaK Platform works through a deep neural network trained to detect hyperkalemia based on data from electrocardiograms (ECG) similar to those captured by the Company's KardiaMobile and KardiaBand devices.

Biologic Use Linked to Reduced Cardiovascular Risk in Inflammatory Arthritis

Biologic Use Linked to Reduced Cardiovascular Risk in Inflammatory Arthritis

By

Current biologic use was associated with a reduction in major cardiovascular events in patients with inflammatory arthritis.

Exposure to Toxic Metals May Increase Cardiovascular Disease Risk

Exposure to Toxic Metals May Increase Cardiovascular Disease Risk

Increased risk of cardiovascular disease and coronary heart disease with exposure to arsenic, lead, cadmium, and copper.

Higher Aldosterone Levels Tied to Incident Type 2 Diabetes Risk

Higher Aldosterone Levels Tied to Incident Type 2 Diabetes Risk

Racial/ethnic differences were seen in the association of aldosterone with incident type 2 diabetes.

Tiotropium Associated With Increased Cardiovascular Risk in COPD

Tiotropium Associated With Increased Cardiovascular Risk in COPD

By

Cardiovascular risk within 30 days of therapy start was approximately 2-fold higher with the incident use of tiotropium in COPD.

Widespread Statin Use Not Recommended in Old, Very Old

Widespread Statin Use Not Recommended in Old, Very Old

No benefit in healthy elderly patients; the protective effect is limited to those with type 2 diabetes aged 75 to 84 years.

Cardiovascular Health Risks Identified With Diclofenac Use

Cardiovascular Health Risks Identified With Diclofenac Use

By

To investigate the cardiovascular risks associated with diclofenac, researchers conducted a series of cohort studies mimicking the design criteria of a clinical trial.

Cardiovascular Disease Google Searches Peak in Winter

Cardiovascular Disease Google Searches Peak in Winter

Seasonal patterns of relative search volumes were seen for queries relating to cardiovascular disease.

High and Low Carbohydrate Diets Linked to Increased Mortality

High and Low Carbohydrate Diets Linked to Increased Mortality

Increase in mortality when carbohydrates were exchanged for animal-derived fat or protein.

Vascular Risk Factors for Brain Calcification in Seniors Identified

Vascular Risk Factors for Brain Calcification in Seniors Identified

Hippocampal calcifications were associated with diabetes and smoking in patients visiting a memory clinic.

Partial Oral Antibiotics Noninferior to Continuous IV in Left-Sided Endocarditis

Partial Oral Antibiotics Noninferior to Continuous IV in Left-Sided Endocarditis

Changing to oral antibiotics was noninferior to continued intravenous antibiotic treatment in left-sided endocarditis.

Age at Onset of Type 1 Diabetes Effects Mortality and Cardiovascular Complications

Age at Onset of Type 1 Diabetes Effects Mortality and Cardiovascular Complications

By

Investigators examine whether age of onset of type 1 diabetes affects mortality and cardiovascular risk.

IL-6 Receptor Polymorphisms May Be Associated With Aortic Aneurysm Risk

IL-6 Receptor Polymorphisms May Be Associated With Aortic Aneurysm Risk

By

Identification of interleukin 6 receptor single-nucleotide polymorphisms was associated with a significantly reduced risk for aortic aneurysm phenotypes.

Assessing the Evidence of Aspirin for Primary Prevention in Diabetes

Assessing the Evidence of Aspirin for Primary Prevention in Diabetes

By

The substantial burden of cardiovascular disease in patients with diabetes has led to the exploration of various cardiovascular disease prevention strategies, including the use of aspirin.

Breastfeeding Linked to Lower Risk of Stroke After Menopause

Breastfeeding Linked to Lower Risk of Stroke After Menopause

Stroke risk 19% lower with breastfeeding for 1 to 6 months, and there was a stronger link for longer duration.

Lorcaserin Facilitates Weight Loss Without Increasing Risk of Major CV Events

Lorcaserin Facilitates Weight Loss Without Increasing Risk of Major CV Events

By

In the CAMELLIA-TIMI 61 study, 12,000 overweight or obese patients with atherosclerotic cardiovascular disease or multiple cardiovascular risk factors were randomized to receive either lorcaserin 10mg twice daily or placebo.

Does Aspirin Cut the Risk of Initial Vascular Events in Patients at Moderate CVD Risk?

Does Aspirin Cut the Risk of Initial Vascular Events in Patients at Moderate CVD Risk?

For this double-blind, placebo-controlled study, researchers selected male patients ≥55 years and female patients ≥60 years with average cardiovascular risk and assigned them to enteric-coated aspirin 100mg (N=6270) or placebo (N=6276) once daily; the median follow-up time was 60 months.

Cardiovascular Health Tied to Dementia Risk in Older Adults

Cardiovascular Health Tied to Dementia Risk in Older Adults

Having optimal levels in more measures of cardiovascular health is linked to lower dementia risk.

Xenon Gas for Inhalation Therapy Gets Fast-Tracked for Post-Cardiac Arrest Syndrome

Xenon Gas for Inhalation Therapy Gets Fast-Tracked for Post-Cardiac Arrest Syndrome

By

Treatment with xenon may improve functional outcomes and reduce mortality in cardiac arrest survivors.

FDA Bans E-Cig Liquid Products That Look Like Snacks, Candies

FDA Bans E-Cig Liquid Products That Look Like Snacks, Candies

Labels and ads for the nicotine-containing e-liquids were false or misleading, and potentially dangerous.

Optimal Dressing, Securement of Peripheral IV Catheters Not Yet Found

Optimal Dressing, Securement of Peripheral IV Catheters Not Yet Found

By

Tissue adhesive with polyurethane dressing, bordered polyurethane dressing, or using a securement device with polyurethane dressing were not superior to standard low-cost polyurethane dressing for peripheral intravenous catheters.

In-Hospital Cardiac Arrest Long-Term Survival Lower in Blacks

In-Hospital Cardiac Arrest Long-Term Survival Lower in Blacks

Black survivors of in-hospital cardiac arrest have lower survival at 1, 3, and 5 years vs whites.

Link Between Gestational Diabetes and Risk for CVD and Diabetes in Hispanic/Latina Population

Link Between Gestational Diabetes and Risk for CVD and Diabetes in Hispanic/Latina Population

By

Investigators sought to compare cardiovascular risk and disease prevalence in the Hispanic and Latina population in the United States with and without a history of gestational diabetes.

Sign Up for Free e-Newsletters