Metabolic

New Data Support Long-Term Cardiovascular Safety of Linagliptin in T2D

New Data Support Long-Term Cardiovascular Safety of Linagliptin in T2D

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Results showed the overall safety profile of linagliptin in study patients, including adults with kidney disease, was consistent with previous data.

Results From Long-Term Cardiovascular Safety Study of Lorcaserin Announced

Results From Long-Term Cardiovascular Safety Study of Lorcaserin Announced

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Approximately 12,000 patients took part in the CAMELLIA-TIMI 61 trial in which participants were randomized to either lorcaserin HCl 10mg twice daily or placebo.

Mothers' Healthy Lifestyle Tied to Drop in Offspring Obesity

Mothers' Healthy Lifestyle Tied to Drop in Offspring Obesity

Lower risk for incident obesity in offspring whose mothers have healthy BMI and engage in physical activity.

AMA Adopts Policy to Cut Sugar Sweetened Drink Consumption

AMA Adopts Policy to Cut Sugar Sweetened Drink Consumption

The policy supports evidence-based strategies such as excise taxes and adding warning labels.

Beta-Blockers Show Varied Effects on Hypoglycemic Mortality Risk in Diabetes

Beta-Blockers Show Varied Effects on Hypoglycemic Mortality Risk in Diabetes

Investigators examined the relationship between the use of β-blockers and incidence of hypoglycemia and risk for mortality in hospitalized patients with diabetes.

ITCA 650 Shows Efficacy in Reducing Weight, HbA1c in Type 2 Diabetes

ITCA 650 Shows Efficacy in Reducing Weight, HbA1c in Type 2 Diabetes

The ITCA 650, a small titanium osmotic mini-pump, provides a subcutaneous infusion of exenatide over 3 or 6 months.

SGLT2 Inhibitor Use Linked to Lower Risk for Heart Failure, Death in Type 2 Diabetes

SGLT2 Inhibitor Use Linked to Lower Risk for Heart Failure, Death in Type 2 Diabetes

Regardless of presence of preexisting cardiovascular disease, SGLT2 inhibitors were associated with lower risk for death and heart failure.

Cardiovascular Event Risk Down With Med Diet Plus Olive Oil, Nuts

Cardiovascular Event Risk Down With Med Diet Plus Olive Oil, Nuts

Lower incidence of major cardiovascular events with Mediterranean diet supplemented with oil and nuts.

Fenofibrate Improves Cholesterol Levels in Type 2 Diabetes

Fenofibrate Improves Cholesterol Levels in Type 2 Diabetes

To understand the mechanism underlying the benefit of fenofibrate on vascular complications in patients with type 2 diabetes, investigators assessed carotid intima thickness as a marker of subclinical atherosclerosis.

Good Sleep Tied to Better Cardiometabolic Health in Youths

Good Sleep Tied to Better Cardiometabolic Health in Youths

Longer sleep duration and greater sleep efficiency linked to better metabolic risk scores in adolescents.

Plasma Methylglyoxal Levels Associated With CVD, Mortality in Type 2 Diabetes

Plasma Methylglyoxal Levels Associated With CVD, Mortality in Type 2 Diabetes

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Investigators sought to determine whether methylglyoxal levels are associated with cardiovascular disease in type 2 diabetes.

Clinician Perspective: Examining the Link Between Antipsychotics and Diabetes

Clinician Perspective: Examining the Link Between Antipsychotics and Diabetes

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Endocrinologist Kevin M. Pantalone, DO, and psychiatrist Christian Kohler, MD, discuss the risk associated with the use of antipsychotic medications in individuals with type 2 diabetes.

Emotional Hyper-Reactivity and Cardiometabolic Risk in Remitted Bipolar Disorder

Emotional Hyper-Reactivity and Cardiometabolic Risk in Remitted Bipolar Disorder

Patients with remitted bipolar disorder and emotional hyper-reactivity also have significantly higher levels of low-grade inflammation, hypertension, and impaired glucose metabolism, indicating a higher risk for cardiometabolic dysfunction.

Cardiovascular Mortality in Individuals With Early-, Late-Onset Prediabetes

Cardiovascular Mortality in Individuals With Early-, Late-Onset Prediabetes

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Investigators examined the frequency of cardiovascular vs noncardiovascular deaths in individuals who developed prediabetes that did not progress to diabetes.

Effect of Testosterone Replacement on Glycemic Control in Obese Men With Hypogonadism, T2D

Effect of Testosterone Replacement on Glycemic Control in Obese Men With Hypogonadism, T2D

Investigators examined the effect of testosterone replacement therapy on metabolic syndrome and vascular function in obese males with hypogonadism.

Job Strain May Raise Death Risk in Men With Cardiometabolic Disease

Job Strain May Raise Death Risk in Men With Cardiometabolic Disease

Increased mortality from job strain was greater than that from hypertension, obesity, physical inactivity, and high alcohol intake.

CVD Risk Up Even in Metabolically Healthy Obese Women

CVD Risk Up Even in Metabolically Healthy Obese Women

Women with metabolically unhealthy normal-weight, overweight, obesity had a considerably higher risk for cardiovascular disease.

Non-Nutritive Sweeteners Do Not Increase Blood Glucose Levels

Non-Nutritive Sweeteners Do Not Increase Blood Glucose Levels

Concentration of non-nutritive sweeteners decreased gradually during the course of observation after consumption.

Antipsychotics Increase Risk for Metabolic Syndrome, CVD in Younger Patients

Antipsychotics Increase Risk for Metabolic Syndrome, CVD in Younger Patients

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Younger patients treated with antipsychotics after experiencing a first episode of psychosis are at an increased risk for metabolic syndrome and cardiovascular disease.

Reforms Suggested for Improving Medical Nutrition Education

Reforms Suggested for Improving Medical Nutrition Education

Enhancing physician training will increase engagement in diet counseling for patients with ASCVD.

Metabolically Healthy Obesity Not Without Risk for CVD

Metabolically Healthy Obesity Not Without Risk for CVD

Findings showed that metabolically healthy obesity is transient, so it is not a reliable predictor of lower cardiovascular risk in the future.

Five Healthy Lifestyle Habits Could Add More Than 10 Years to Life

Five Healthy Lifestyle Habits Could Add More Than 10 Years to Life

The healthy lifestyle habits reduced the risk for all-cause, cancer, and cardiovascular mortality for adults with 5 vs 0 low-risk factors.

Evening Preference Linked to Higher BMI in Type 2 Diabetes

Evening Preference Linked to Higher BMI in Type 2 Diabetes

Breakfast time mediates the association between morning-evening preference and body mass index in type 2 diabetes.

Aortic Stiffness, Concentric LV Remodeling Linked in T2DM

Aortic Stiffness, Concentric LV Remodeling Linked in T2DM

Aortic distensibility was independently linked to concentric left ventricular remodeling in patients with type 2 diabetes.

Social Support of Autonomy Tied to Better Glycemic Control in Diabetes

Social Support of Autonomy Tied to Better Glycemic Control in Diabetes

Findings suggest family and friends' support of autonomy also lowers diabetes distress.

Increased Risk for Mortality in People With Diabetes, CHD Taking Beta-Blockers

Increased Risk for Mortality in People With Diabetes, CHD Taking Beta-Blockers

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Further studies are needed to assess whether beta-blockers are effective in reducing mortality and coronary events in patients with diabetes receiving optimal medical treatment.

Metabolic Syndrome Common With Chronic Hepatitis B Infection

Metabolic Syndrome Common With Chronic Hepatitis B Infection

Metabolic syndrome was also associated with higher alanine aminotransferase levels longitudinally.

One-Hour Plasma Glucose Useful Predictor of Diabetic Retinopathy

One-Hour Plasma Glucose Useful Predictor of Diabetic Retinopathy

The 1-hour test is as effective as the 2-hour test in its predictive ability

Higher Mortality Risk Seen for 'Night Owls'

Higher Mortality Risk Seen for 'Night Owls'

Individuals with an evening preference had a higher risk for mortality and metabolic dysfunction.

Pharmacists Can Help With Diabetes Management via Telemedicine

Pharmacists Can Help With Diabetes Management via Telemedicine

Telemedicine could provide a real-time feedback loop and allow pharmacists to help patients self-manage their diabetes.

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