Metabolic

Insulin Resistance, Cardiometabolic Risk Increased in Obese Children

Insulin Resistance, Cardiometabolic Risk Increased in Obese Children

Cardiometabolic risk and homeostatic model assessment of insulin resistance increase with increased body mass index.

Insulin Dose Not Tied to Cardiovascular Outcomes

Insulin Dose Not Tied to Cardiovascular Outcomes

Cardiovascular outcomes in patients with diabetes are not explained by insulin resistance.

Fasting Blood Glucose Patterns May Predict Future Myocardial Infarction

Fasting Blood Glucose Patterns May Predict Future Myocardial Infarction

For individuals without diabetes, certain fasting blood glucose trajectories are associated with the risk of future myocardial infarction.

Cardiovascular Risk in Type 2 Diabetes Not Increased With Exenatide

Cardiovascular Risk in Type 2 Diabetes Not Increased With Exenatide

The risk of major cardiovascular events is similar for those receiving exenatide or placebo for patients with type 2 diabetes.

Metabolically Healthy Obese Individuals Still at Higher Risk for CV Events

Metabolically Healthy Obese Individuals Still at Higher Risk for CV Events

Metabolically healthy obese individuals have increased risk of coronary heart disease, cerebrovascular disease than those of normal weight.

Cardiovascular Risk Factors in Cross-Sex Hormone Therapy: Expert Opinion

Cardiovascular Risk Factors in Cross-Sex Hormone Therapy: Expert Opinion

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In a meta-analysis of cross-sex hormone therapy use in transgender individuals, researchers found that transgender women may have a greater risk for CVD mortality vs cisgender women in the general population.

Higher Intake of Carbohydrates May Increase Risk for Premature Death

Higher Intake of Carbohydrates May Increase Risk for Premature Death

An excess of carbohydrates may be to blame for higher risk of premature deaths, not fats.

Cardiovascular Disease Risk and Dietary Fat Intake: Update and Expert Roundtable

Cardiovascular Disease Risk and Dietary Fat Intake: Update and Expert Roundtable

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The American Heart Association has shifted its dietary recommendations from replacing total fat with carbohydrates to replacing saturated and trans fats with unsaturated fat.

Type 2 Diabetes Medication Adherence Not Reported in Studies

Type 2 Diabetes Medication Adherence Not Reported in Studies

Studies often fail to include information on outcomes by medication adherence in type 2 diabetes.

Body Mass Index in Childhood May Predict Stroke Risk in Adulthood

Body Mass Index in Childhood May Predict Stroke Risk in Adulthood

Above-average childhood body mass index are associated with increased risk of early adult ischemic stroke.

After Cardiac Surgery, Patients With Obesity Require More ICU Resources

After Cardiac Surgery, Patients With Obesity Require More ICU Resources

For patients undergoing cardiac surgery, increasing obesity is associated with increased intensive care unit resource utilization.

Insulin Initiation Associated With Weight Gain, Acitvity Decreases in T2D

Insulin Initiation Associated With Weight Gain, Acitvity Decreases in T2D

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Initiation of insulin therapy in patients with type 2 diabetes was associated to inactivity and weight gain.

Multiple Cardiometabolic Comorbidities Prevalent in Psoriasis

Multiple Cardiometabolic Comorbidities Prevalent in Psoriasis

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Patients with psoriasis have high rates of cardiometabolic comorbidities.

Obesity, Overweight Associated With Higher Healthcare Costs

Obesity, Overweight Associated With Higher Healthcare Costs

Excess weight is associated with increased costs across health care settings.

USPSTF Updated Guidelines on Behavioral Counseling for CVD Prevention, Plus Expert Interview

USPSTF Updated Guidelines on Behavioral Counseling for CVD Prevention, Plus Expert Interview

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An overview of new USPSTF recommendations for behavioral lifestyle counseling for the prevention of cardiovascular disease plus an expert interview.

Diabetes Increases Hospital Readmissions Rates

Diabetes Increases Hospital Readmissions Rates

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Patients with diabetes had a higher rate of readmission to hospitals compared with patients without diabetes.

Hypertension, Type 2 Diabetes Risk Increases With Slow, Steady Weight Gain

Hypertension, Type 2 Diabetes Risk Increases With Slow, Steady Weight Gain

Slow and steady weight gain in early or middle adulthood can increase risk of chronic diseases like hypertension.

Two-Hour Postload Glucose Predicts CV Events Better Than Fasting Glucose, HbA1C

Two-Hour Postload Glucose Predicts CV Events Better Than Fasting Glucose, HbA1C

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Two-hour postload glucose (2h-PG) may be a better predictor of cardiovascular events in patients with coronary artery disease.

Heart Failure Risk Increases With Weight Gain

Heart Failure Risk Increases With Weight Gain

Even a little weight gain can increase risk of developing heart failure, but people who lost weight were more likely to have a decrease in the thickness of their heart muscle.

FDA Tentatively Approves Follow-On Biologic Basal Insulin Glargine

FDA Tentatively Approves Follow-On Biologic Basal Insulin Glargine

Tentative FDA approval has been granted to Merck's follow-on biologic basal insulin injection, Lusduna Nexvue.

CVD Risk in Diabetes Predicted by Visceral to Subcutaneous Fat Area Ratio

CVD Risk in Diabetes Predicted by Visceral to Subcutaneous Fat Area Ratio

In patients with increasing visceral to subcutaneous fat area ratio quartiles, there were more first or recurring cardiovascular disease.

Glycemic Control Improves With Hepatitis C Treatment

Glycemic Control Improves With Hepatitis C Treatment

Direct-acting antiviral treatment for hepatitis C virus is linked to improved glycemic control in patients with type 2 diabetes.

Chronic Inflammatory Disorders Increase Cardiometabolic and Mortality Risks

Chronic Inflammatory Disorders Increase Cardiometabolic and Mortality Risks

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The degree of risk for cardiometabolic events and all-cause mortality increased with nonsteroidal anti-inflammatory drugs and corticosteroid drugs.

E-Cigarettes Have Same Metabolic Affects as Regular Cigarettes

E-Cigarettes Have Same Metabolic Affects as Regular Cigarettes

The deleterious effects of electronic cigarettes on weight and metabolic profile is similar to traditional cigarettes.

Higher BMI During Adolescence May Increase Stroke Risk

Higher BMI During Adolescence May Increase Stroke Risk

An increase in body mass index during puberty and adolescence may be a risk factor for stroke later in life.

CVD Risk in Type 1 Diabetes Improved With Metformin

CVD Risk in Type 1 Diabetes Improved With Metformin

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Metformin therapy in type 1 diabetes may improved cardiovascular disease risk management.

FDA to Review Insulin Degludec for Cardiovascular Safety

FDA to Review Insulin Degludec for Cardiovascular Safety

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Novo Nordisk submitted an application to the FDA with data on the cardiovascular safety of an insulin degludec.

Activity Levels in US Teens and Older Adults

Activity Levels in US Teens and Older Adults

Physical activity levels among children and teens are lower than previously thought.

Systolic Blood Pressure Variability Independently Predicts CV Events and Death in Diabetes

Systolic Blood Pressure Variability Independently Predicts CV Events and Death in Diabetes

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Visit-to-visit systolic blood pressure variability may be a better predictor of cardiovascular events and death than traditional risk factors.

Cholesterol Significantly Reduced by Blocking Angiopoietin-like 3 Gene

Cholesterol Significantly Reduced by Blocking Angiopoietin-like 3 Gene

Two research groups successfully reduced cholesterol in humans to block the angiopoietin-like 3 gene.

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