Heart Failure

Spironolactone Oral Suspension Formulation Approved by FDA

Spironolactone Oral Suspension Formulation Approved by FDA

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The FDA has approved CaroSpir, the first oral liquid formulation of spironolactone for hypertension and heart failure treatment.

Beta-Blockers Reduce CV Mortality in Heart Failure With Preserved Ejection Fraction

Beta-Blockers Reduce CV Mortality in Heart Failure With Preserved Ejection Fraction

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Most pharmacotherapies appear not to have significant effect on all-cause or cardiovascular mortality in heart failure with preserved ejection fraction.

Gene Editing May Provide New Treatment Option for Hypertrophic Cardiomyopathy

Gene Editing May Provide New Treatment Option for Hypertrophic Cardiomyopathy

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Researchers have used a gene-editing tool to repair the segment of DNA that causes hypertrophic cardiomyopathy.

Aspirin May Be Safe to Administer in Heart Failure

Aspirin May Be Safe to Administer in Heart Failure

Patients who took aspirin daily were not at a higher risk for heart failure complications compared with patients who took warfarin.

Higher Sodium Intake Linked to Adverse Cardiac Remodeling

Higher Sodium Intake Linked to Adverse Cardiac Remodeling

An estimated sodium intake of 3.7 g/day or above is associated with left ventricular longitudinal strain, circumferential strain, and e' velocity.

Case Study: Substernal Chest Pressure in a Young Man

Case Study: Substernal Chest Pressure in a Young Man

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A young man presents with 1-day onset of acute substernal chest pressure. Can you identify its cause?

Shortness of Breath and Palpitations After a Funeral: Depression or Something Worse?

Shortness of Breath and Palpitations After a Funeral: Depression or Something Worse?

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An elderly woman with comorbidities presents with chest pressure and shortness of breath after a stressful event and personal loss. Can you identify the correct diagnosis?

Left Ventricular Function in Type 1 Diabetes Improves With Exercise

Left Ventricular Function in Type 1 Diabetes Improves With Exercise

Adolescents with type 1 diabetes may benefit from a 20 week exercise training intervention that's associated with improved aerobic capacity and stroke volume.

Reducing Hospital Readmissions for Heart Failure, MI Did Not Increase Mortality Rates

Reducing Hospital Readmissions for Heart Failure, MI Did Not Increase Mortality Rates

Reducing hospital readmission rates for acute myocardial infarction, heart failure, and pneumonia didn't increase mortality rates, and may even have lowered death rates.

Heart Failure in Type 2 Diabetes: Improving the Risk Model

Heart Failure in Type 2 Diabetes: Improving the Risk Model

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N-terminal pro-B-type natriuretic peptide showed the strongest association with heart failure in patients with type 2 diabetes.

Heart Failure Risk Increases With Weight Gain

Heart Failure Risk Increases With Weight Gain

Even a little weight gain can increase risk of developing heart failure, but people who lost weight were more likely to have a decrease in the thickness of their heart muscle.

Managing Heart Failure: Improving Quality of Life and Preventing Excerbations

Managing Heart Failure: Improving Quality of Life and Preventing Excerbations

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Heart failure is the number 1 reason for patient re-admittance to acute-care facilities according to the American Heart Association.

Sudden Death Rates in Heart Failure on the Decline

Sudden Death Rates in Heart Failure on the Decline

Sudden death from heart failure rates have declined over the past 2 decades.

Sudden Death in Cardiomyopathy Reduced With ICD Treatment

Sudden Death in Cardiomyopathy Reduced With ICD Treatment

ICD therapy reduced the incidence of sudden and all-cause mortality in comparison to conventional care for ischemic or nonischemic cardiomyopathy.

Earlier Loop Diuretic Use Leads to Reduced Mortality in Heart Failure

Earlier Loop Diuretic Use Leads to Reduced Mortality in Heart Failure

Early treatment with loop diuretics is linked to lower in-hospital mortality in acute heart failure patients.

Childhood Asthma Linked With Increased Left Ventricular Mass In Adulthood

Childhood Asthma Linked With Increased Left Ventricular Mass In Adulthood

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Greater left ventricle mass and left ventricle mass indexed to height were found in participants with a history of childhood asthma.

Hospitalizations for Heart Failure On the Decline

Hospitalizations for Heart Failure On the Decline

While hospitalizations for heart failure have declined overall, rates are still 2.5 times higher among blacks vs whites.

Heart Failure Risk in Women With Afib

Heart Failure Risk in Women With Afib

Researchers found four modifiable factors that account for heart failure risk in women with atrial fibrillation.

Can Beta-Blockers Reduce Mortality in Acute Myocardial Infarction Without Heart Failure?

Can Beta-Blockers Reduce Mortality in Acute Myocardial Infarction Without Heart Failure?

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In patients with acute myocardial infarction without heart failure, beta-blockers did not reduce mortality risk at 1 year.

Subclinical Myocardial Damage in Obesity May Be Mitigated by Physical Activity

Subclinical Myocardial Damage in Obesity May Be Mitigated by Physical Activity

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Individuals who had the lowest levels of recommended physical activity had elevated levels of high-sensitivity cardiac troponin T.

Heart Damage Can Be Reversed in Former Methamphetamine Users

Heart Damage Can Be Reversed in Former Methamphetamine Users

After discontinuing methamphetamine use, study participants showed reverse signs of heart damage.

Exercise Capacity in Heart Failure With Reduced Ejection Fraction Not Improved With Iron Supplementation

Exercise Capacity in Heart Failure With Reduced Ejection Fraction Not Improved With Iron Supplementation

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Patients with heart failure with reduced ejection fraction and iron deficiency do not benefit from iron supplementation.

Acute Heart Failure Mortality Increased With Morphine

Acute Heart Failure Mortality Increased With Morphine

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Patients with acute heart failure who received intravenous morphine in the emergency department had higher mortality compared with patients who did not receive morphine.

Early Menopause Linked to Higher Risk of Heart Failure

Early Menopause Linked to Higher Risk of Heart Failure

Women who undergo early menopause or never gave birth may have an increased risk of heart failure.

Heart Failure Risk Increased With Fewer Menstrual Cycles

Heart Failure Risk Increased With Fewer Menstrual Cycles

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Women with fewer menstrual cycles are at a higher risk for incident heart failure.

Ivabradine in Heart Failure With Preserved Ejection Fraction

Ivabradine in Heart Failure With Preserved Ejection Fraction

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Ivabradine did not improve exercise capacity, diastolic function, or NT-proBNP levels in patients with heart failure with preserved ejection fraction.

Heart Failure Society of America Joins ACC and AHA to Update Heart Failure Guidelines

Heart Failure Society of America Joins ACC and AHA to Update Heart Failure Guidelines

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The American College of Cardiology, the American Heart Association, and the Heart Failure Society of America joined forces to update the previous 2013 heart failure treatment guidelines.

Newly Diagnosed Atrial Fibrillation Benefits From Rivaroxaban, Dabigatran

Newly Diagnosed Atrial Fibrillation Benefits From Rivaroxaban, Dabigatran

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Direct oral anticoagulation reduced the risk of congestive heart failure admissions and all-cause mortality in both genders.

Parenteral Nutrition in Comorbid Congestive Heart Failure Outcomes

Parenteral Nutrition in Comorbid Congestive Heart Failure Outcomes

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Patients with comorbid congestive heart failure who received parenteral nutrition experienced increased negative outcomes in their hospital stay.

HIV Infection's Impact on HF: Reduced EF vs Preserved EF in ART

HIV Infection's Impact on HF: Reduced EF vs Preserved EF in ART

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HIV poses higher risks of heart failure even at younger ages of infection, and 25% of all new cases in the United States occur in people between age 13 and 24.

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