Genetics

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ARVD/Cardiomyopathy: Interview with Expert Hugh Calkins, MD

ARVD/Cardiomyopathy: Interview with Expert Hugh Calkins, MD

While ARVD/C management has greatly improved, more precautions—particularly in genetic testing and exercise—need to be taken.

Latest News

IL-6 Receptor Polymorphisms May Be Associated With Aortic Aneurysm Risk

IL-6 Receptor Polymorphisms May Be Associated With Aortic Aneurysm Risk

Identification of interleukin 6 receptor single-nucleotide polymorphisms was associated with a significantly reduced risk for aortic aneurysm phenotypes.

Familial Hypercholesterolemia Benefits From Genetic Screening

Familial Hypercholesterolemia Benefits From Genetic Screening

Genetic screening for familial hypercholesterolemia would improve the likelihood of a definitive diagnosis and may help clinicians choose the appropriate therapy for patients.

Genetic Screening in Preventive Care: Advances and Challenges

Genetic Screening in Preventive Care: Advances and Challenges

Approximately 1% of individuals in the United States have a genetic predisposition to cancer or heart disease, and these individuals could be ideal candidates for genetic screening.

Leukocyte Telomere Length as Potential Biomarker for Atrial Fibrillation

Leukocyte Telomere Length as Potential Biomarker for Atrial Fibrillation

No significant association was found between atrial fibrillation risk and leukocyte telomere length.

Gene Editing May Provide New Treatment Option for Hypertrophic Cardiomyopathy

Gene Editing May Provide New Treatment Option for Hypertrophic Cardiomyopathy

Researchers have used a gene-editing tool to repair the segment of DNA that causes hypertrophic cardiomyopathy.

Coronary Artery Disease and Serum Calcium Levels: Is There a Genetic Connection?

Coronary Artery Disease and Serum Calcium Levels: Is There a Genetic Connection?

A genetic predisposition to elevated serum calcium levels may increase the risk for coronary artery disease and myocardial infarction.

Genetic Variants May Explain High Sodium Consumption

Genetic Variants May Explain High Sodium Consumption

Individuals with 1 or 2 dominant G alleles of rs713598 in the TAS2R38 gene were 1.9 times more likely to consume sodium >2.3 g/d.

Fewer Than 2% of Severe Hypercholesterolemia Cases Related to Familial Hypercholesterolemia

Fewer Than 2% of Severe Hypercholesterolemia Cases Related to Familial Hypercholesterolemia

While fewer than 2% of severe hypercholesterolemia cases can be linked to familial hypercholesterolemia mutations, the latter does increase risk for coronary artery disease.

CYP2C19 Gene Not Related to Cardiovascular Outcomes in ACS Patients

CYP2C19 Gene Not Related to Cardiovascular Outcomes in ACS Patients

Genetic testing did not affect decisions regarding the use of clopidogrel or prasugrel in patients with acute coronary syndromes.

ALPK3 Biallelic Mutations Implicated in Pediatric Cardiomyopathy

ALPK3 Biallelic Mutations Implicated in Pediatric Cardiomyopathy

Patients with biallelic mutations in ALPK3 presented with severe hypertrophic and/or dilated cardiomyopathy.

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