James E. Loyd, MD, and Wendy Chung, MD, PhD, offer insight into the role of genetics in pulmonary arterial hypertension.
While ARVD/C management has greatly improved, more precautions—particularly in genetic testing and exercise—need to be taken.
Researchers have used a gene-editing tool to repair the segment of DNA that causes hypertrophic cardiomyopathy.
A genetic predisposition to elevated serum calcium levels may increase the risk for coronary artery disease and myocardial infarction.
Individuals with 1 or 2 dominant G alleles of rs713598 in the TAS2R38 gene were 1.9 times more likely to consume sodium >2.3 g/d.
While fewer than 2% of severe hypercholesterolemia cases can be linked to familial hypercholesterolemia mutations, the latter does increase risk for coronary artery disease.
Genetic testing did not affect decisions regarding the use of clopidogrel or prasugrel in patients with acute coronary syndromes.
Patients with biallelic mutations in ALPK3 presented with severe hypertrophic and/or dilated cardiomyopathy.
Neurological disorders in perinatal LQTS patients may be caused by neurological phenotypes associated with severe cardiac phenotypes.
Shared Genetic Predisposition Between Peripartum Cardiomyopathy and Idiopathic Dilated Cardiomyopathy
Peripartum cardiomyopathy shares genetic predisposition, TTN truncating variants, with both idiopathic and familial cardiomyopathy.
Hypocretin (orexin) receptor-2, a new genetic contribution to heart failure may have promising treatment effects.
Ten new genes have been found to be associated with coronary artery disease susceptibility.
The Cardiology Advisor Articles
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- Timing of BP Measurements in Orthostatic Hypotension Linked to Adverse Effects
- Hypertension, Diabetes in Midlife Increase Risk of Dementia
- Reduced GFR Associated With Increased Atrial Fibrillation Risk
- Spironolactone Oral Suspension Formulation Approved by FDA
- Assessing Chest Pain in ER With Short-term Risk Stratification Tool
- Cardiac Rehabilitation: Changes, Challenges, and Clinician Perspectives
- Shortness of Breath and Palpitations After a Funeral: Depression or Something Worse?
- Newly Diagnosed Atrial Fibrillation Benefits From Cardiology Care vs Primary Care
- Noncalcified, High-Risk Coronary Plaque Burden Increased With Psoriasis
- Case Study: Cardiac Manifestations of Rheumatoid Arthritis
- Preventing Venous Thromboembolism After Hip, Knee Arthoplasty: Comparing Anticoagulant Efficacy
- Patients Report Breakdowns in Hospital Care
- Evolocumab Added to Statin Therapy Does Not Affect Cognition
- Risk Stratification Using Platelet Aggregation in Stable CAD